The theoretical biology movement originating in Britain in the early 1930’s and the biosemiotics movement which took off in Europe in the 1980’s have much in common. They are both committed to replacing the neo-Darwinian synthesis, and they have both invoked theories of signs to this end. Yet, while there has been some mutual appreciation and influence, particularly in the cases of Howard Pattee, René Thom, Kalevi Kull, Anton Markoš and Stuart Kauffman, for the most part, these movements have developed (...) independently of each other. Focussing on morphogenesis understood as vegetative semiosis, in this paper I will argue that the ideas of these movements are commensurate. Furthermore, synthesising them would enable us to see life processes as proto-narratives. Doing so will involve synthesising biohermeneutics, Peircian biosemiotics with Waddington’s theoretical biology and Piagetian genetic structuralism, and this, I claim, would strengthen the challenge of these traditions to mainstream biology. At the same time, this should contribute to overcoming the opposition between the sciences and the humanities, developing a broader tradition of Schellingian thought which involves developing the humanities and then demanding of the physical and biological sciences that they are consistent with and can make intelligible the emergence of humans as conceived by the humanities. (shrink)

John Dupré explores recent revolutionary developments in biology and considers their relevance for our understanding of human nature and human society. Epigenetics and related areas of molecular biology have eroded the exceptional status of the gene and presented the genome as fully interactive with the rest of the cell. Developmental systems theory provides a space for a vision of evolution that takes full account of the fundamental importance of developmental processes. Dupré shows the importance of microbiology for a proper (...) understanding of the living world, and reveals how it subverts such basic biological assumptions as the organisation of biological kinds on a branching tree of life, and the simple traditional conception of the biological organism. (shrink)

Dewey proposed a new theory of language, in which the form (such as symbols) and content of language are not separated. The content of language includes the physical aspects of the world, which are purely quantitative: the life process, which involves functional responses to qualities, and the human life process, which involves the conscious integration of the potentiality of qualities to form a functional whole. The pinnacle of this process is individuality, or the emergence of a unique function (...) to change social habits through a democratic process. However, there is a real danger that the form and content of language become split. To prevent such a split, Dewey proposed education through the basic occupations of the production of food, clothing and shelter. (shrink)

The thesis advanced in this book is that feeling and cognition actualize through a process that originates in older brain formations and develops outward through limbic and cortical fields through the self-concept and private space into (as) the world. An iteration of this transition deposits acts, objects, feelings and utterances. Value is a mode of conceptual feeling that depends on the dominant phase in this transition: from desire through interest to object worth. Among the topics covered are subjective time and (...) change, the epochal nature of objects and their temporal extensibility and the evolution of value from inorganic matter into organic form. The theory of microgenesis informs this work. According to this theory, acts and objects evolve in milliseconds through phases that replicate patterns in forebrain evolution. The progression in the actualization of the mind/brain state is from archaic to recent in brain formation, from unity to diversity, from past to present and from mind to world. An account is given of the diversity of felt experience avoiding the reductionist moves characteristic of biological materialism and the inherent dualism of psychoanalytic and related theories. This book is intended for any reader interested in the psychology of the inner life and philosophy of mind, including philosophers, psychologists, psychiatrists and others with an interest in problems of value and moral feeling. (shrink)

John Dupr explores recent revolutionary developments in biology and considers their relevance for our understanding of human nature and society. He reveals how the advance of genetic science is changing our view of the constituents of life, and shows how an understanding of microbiology will overturn standard assumptions about the living world.

In this article, we report findings from a qualitative study that explored how the relatives of intensive care unit patients experienced the nurses’ role and relationship with them in the end-of-life decision-making processes. In all, 27 relatives of 21 deceased patients were interviewed about their experiences in this challenging ethical issue. The findings reveal that despite bedside experiences of care, compassion and comfort, the nurses were perceived as vague and evasive in their communication, and the relatives missed a (...) long-term perspective in the dialogue. Few experienced that nurses participated in meetings with doctors and relatives. The ethical consequences imply increased loneliness and uncertainty, and the experience that the relatives themselves have the responsibility of obtaining information and understanding their role in the decision-making process. The relatives therefore felt that the nurses could have been more involved in the process. (shrink)

The aim of this book is to show how supramolecular complexity of cell organization can dramatically alter the functions of individual macromolecules within a cell. The emergence of new functions which appear as a consequence of supramolecular complexity, is explained in terms of physical chemistry. The book is interdisciplinary, at the border between cell biochemistry, physics and physical chemistry. This interdisciplinarity does not result in the use of physical techniques but from the use of physical concepts to study biological problems. (...) In the domain of complexity studies, most works are purely theoretical or based on computer simulation. The present book is partly theoretical, partly experimental and theory is always based on experimental results. Moreover, the book encompasses in a unified manner the dynamic aspects of many different biological fields ranging from dynamics to pattern emergence in a young embryo. The volume puts emphasis on dynamic physical studies of biological events. It also develops, in a unified perspective, this new interdisciplinary approach of various important problems of cell biology and chemistry, ranging from enzyme dynamics to pattern formation during embryo development, thus paving the way to what may become a central issue of future biology. (shrink)

The thesis of this paper is that our understanding of life, as reflected in the biological and medical sciences but also in our everyday transactions, has been hampered by an inappropriate metaphysics. The metaphysics that has dominated Western philosophy, and that currently shapes most understanding of life and the life sciences, sees the world as composed of things and their properties. While these things appear to undergo all kinds of changes, it has often been supposed that this (...) amounts to no more than a change in the spatial relations of their unchanging parts. From antiquity, however, there has been a rival to this view, the process ontology, associated in antiquity with the fragmentary surviving writings of Heraclitus. In the last century it has been especially associated with the work of the British metaphysician and logician, Alfred North Whitehead. For process ontology, what most fundamentally exists is change, or process. What we are tempted to think of as constant things are in reality merely temporary stabilities in this constant flux of change, eddies in the flux of process. My main claim in this paper will be that a metaphysics of this latter kind is the only kind adequate to making sense of the living world. After explaining in more detail, the differences between these ontological views, I shall illustrate the advantages of a process ontology with reference to the category of organism. Finally I shall explore some further implications of a process ontology for biology and for philosophy. (shrink)

Anything within the causal economy of the universe is entirely natural, including values, humans themselves, together with their artifacts and products, and lifespans either as presently the case, or else radically extended. Further, normality of itself is no predicator of normativity. In view of this, arguments concerning the appropriate length of life from naturalness or normalness, are akin to the kind of hardened prejudice manifested by Procrustes in his beliefs concerning the appropriate length of beds, and the sleepers therein. (...) Various modern commentators have taken up the suggestion, initiated in the discourse by Williams, using the example of Karel Capek's opera The Makropulos Secret, that we should not seek to extend life because it will end in boredom. For a person‐process that has achieved self‐resolution, and come to a processual end, for a true Makropulos, there would be no passion, no fear, no affect, no boredom, no disvalue, no wailing. (shrink)

Here, I lay the foundations of a high-level ontology of particulars whose structuring principles differ radically from the 'continuant' vs. 'occurrent' distinction traditionally adopted in applied ontology. These principles are derived from a new analysis of the ontology of “occurring” or “happening” entities. Firstly, my analysis integrates recent work on the ontology of processes, which brings them closer to objects in their mode of existence and persistence by assimilating them to continuant particulars. Secondly, my analysis distinguishes clearly between (...) class='Hi'>processes and events, in order to make the latter abstract objects of thought (alongside propositions). Lastly, I open my ontological inventory to properties and facts, the existence of which is commonly admitted. By giving specific roles to these primitives, the framework allows one to account for static and dynamic aspects of the physical world and for the way that subjects conceive its history: facts account for the life of substances (physical objects and processes), whereas events enable cognitive subjects to account for the life story of substances. (shrink)

Problems raised by complex life cycles for standard summaries of evolutionary processes, and for concepts of individuality in biology, are described. I then outline a framework that can be used to compare life cycles. This framework treats reproduction as a combination of production and recurrence and organizes life cycles according to the distribution of steps in which multiplication, bottlenecks, and sex occur. I also discuss fitness and its measurement in complex life cycles and consider some (...) phenomena that raise complications and difficulties for my framework. (shrink)

Those involved in end-of-life decision making must take into account both legal and ethical issues. This book starts with a critical reflection of ethical principles including ideas such as moral status, the value of life, acts and omissions, harm, autonomy, dignity and paternalism. It then explores the practical difficulties of regulating end-of-life decisions, focusing on patients, healthcare professionals, the wider community and issues surrounding 'slippery slope' arguments. By evaluating the available empirical evidence, the author identifies preferred ways (...) to regulate decisions and minimise abuses at the end of life, and outlines an ethical theory which can provide practical guidance for those engaged in end-of-life decisions"--Provided by publisher. (shrink)

When a group of processes achieves such closure that a set of states of affairs recurs continually, then the effect of that coherence on the world differs from what would occur in the absence of that closure. Such altered effectiveness is an attribute of the system as a whole, and would have consequences. This indicates that the network of processes, as a unit, has ontological significance. Whenever a network of processes generates continual return to a limited set (...) of states of affairs, the system may function as a “whole”— with respect to appropriate interaction partners. The balance achieved by the processes provides the form of definiteness of a unified agent. The causal powers of such coherent aggregates are indeed just the powers of the “constituents acting in concert”. However, the components act in concert in the specific way they do only because of their inclusion in the closed set of interactions that defines the coherence. This renders the causal powers of the coherence defined by that closure non-redundant, and hence the coherence, as a unit, is ontologically significant. The form of definiteness that provides internal coherence also grounds external efficacy of the societal aggregation. The closure is a structural feature of the coherence — possibly, but not necessarily, apparent in spatial structuring. This approach can provide a unified account that includes quantum microphysics, systems biology, and the philosophy of organism ─ without reducing any of these to another. (shrink)

Recent discussions, principally among analytic philosophers, concerning the meaning and the validity of the ‘question of life's meaning’ are significant in several ways. They indicate how analytic philosophy, long charged with sterility, can clarify deeply human questions. They suggest useful avenues of discussion between the analysts and the existentialists, phenomenologists and process philosophers. And they offer some illuminating discriminations between theism and naturalism, and between religious and non-religious understandings of life. But an additional consequence of these discussions is (...) the emergence of a series of challenges to most forms of theism, especially Christianity. In this paper we will be concerned with the latter. (shrink)

The article explores the concept of ‘life’ via processual ontology, contrasting the approaches of substance and processual ontologies, and investigates the link between ontological assumptions and sociopolitical discourses, stating that the predominant substance ontologies also promote an objectifying and anthropocentric framework in sociopolitical discourses and ethical approaches. Arguing for a necessary shift in the ontological conceptualization of life to enable environmentally-minded ethics for the future, the article explores the tie between the sociopolitical discourses embedded in a worldview that (...) is grounded in substance ontology and ethical frameworks. Whilst affirming this tie, this study also explicates the limitations and potential feasibility of a processual understanding of life, in the context of the existential disposition of the self-alienated lived-body self that is ontologically predisposed to objectification as a necessary pre-condition to human self-awareness. (shrink)

Quality improvement mechanisms increasingly use outcome measures to evaluate health care providers. This move toward outcome measures is a radical departure from the traditional focus on process measures. More radical still is the proposal to shift from relatively simple and proximal measures of outcome, such as mortality, to complex outcomes, such as quality of life. While the practical, scientific, and ethical issues associated with the use of outcomes such as mortality and morbidity to compare health care providers have been (...) well rehearsed, the specific concerns associated with the use of quality of life measures in quality of care research have received little attention. As with much research on quality of life there is a tendency to assume that the disadvantages are outweighed by the general virtue of “listening” to patients. In this paper we disagree with this assumption and argue that quality of life is a process, not an outcome. (shrink)

Autistic children with sensory processing differences successfully navigate and engage in meaningful family daily occupations within home and community environments through the support of their family. To date however, much of the research on autistic children with sensory processing differences, has primarily been deficit focused, while much of the caregiver research has focused on issues of distress, burden, effort, and emotional trauma in coping with their child's diagnosis. This study aimed to conduct a qualitative evidence synthesis, using a meta-ethnographic approach (...) to explore the gap identified in understanding successful occupational experiences of family participation and daily family routines when supporting an autistic child with sensory processing differences and to offer an alternative strengths-based perspective. Inclusion criteria were studies which were peer-reviewed qualitative design, published from 2000 to 2021, and that concerned parents/caregivers' perspectives of family occupations of children diagnosed with autism spectrum disorder. Studies were electronically searched in eight databases from October to December 2021 and 23 studies were identified which met the inclusion criteria. Noblit and Hare's seven step approach for conducting analysis in meta-ethnography was used, and three themes identified: sensory processing differences in daily life, what is hard about hard, and orchestrating family life. Results identified the centrality of sensory experiences in understanding family life. Living with unpredictability while orchestrating certainty through routines was core to successful participation. This review provides insights into how parents negotiate the complexities of constructing family life when living with an autistic child. The results can inform the design of future interventions that specifically address the relationship between meaningful participation in family occupations and daily routines and sensory processing in autistic children.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022298938, identifier: CRD42022298938. (shrink)

Whitehead’s metaphysical conception of life in Process and Reality is elucidated. The article is about neither biology nor psychology, but about how Whitehead’s view of interstitial life might account for these scientific disciplines’ range of phenomena. Whitehead’s view of the universe as always novel but rarely original will be clarified, as will the role of eternal objects.

Loneliness has been described as endemic among young people. Such feelings of social isolation ‘even in a crowd’ are likely linked to adverse early life experiences that serve to diminish perceptions of social support and intensify negative social interactions. It was suggested in the present series of survey studies that childhood abuse, which compromises a child’s sense of safety in relationships, may affect social processes that contribute to loneliness in young adulthood. Study 1 assessed different adverse childhood and (...) adult experiences in relation to loneliness among young adults. Linear regression analyses indicated that childhood abuse was uniquely associated with greater loneliness, and this relationship was partially mediated by the perceived availability of social support. Study 2 assessed different forms of childhood abuse and demonstrated that early life emotional abuse was a unique predictor of loneliness, and this relationship was fully mediated by lower perceived support or value in social connections and more frequent unsupportive interactions with friends. Study 3 evaluated the implications of the age of occurrence of abuse. Both emotional and sexual abuse predicted young adult loneliness regardless of age; abuse that was recalled to have occurred at very early ages was not predictive of loneliness over and above consideration of events that happened in older childhood. These relationships were at least partially mediated by perceived social support, social connectedness, and in the case of emotional abuse, unsupportive interactions with friends. Our results add to mounting evidence pointing to the prevalence of loneliness among young adults and the links to adverse early life experiences that may serve to shape appraisals of safety, value, and personal worth in social relationships. (shrink)

The convergence of nano-, bio-, information, and cognitive sciences and technologies (NBIC) is advancing continuously in many societal spheres. This also applies to the manufacturing sector, where technological transformations in robotics push the boundaries of human–machine interaction (HMI). Here, current technological advances in micro- and nanomanufacturing are accompanied by new socio-economic concepts for different sectors of the process industry. Although these developments are still ongoing, the blurring of the boundaries of HMI in processes at the micro- and nano- level (...) can already be observed. According to the authors, these new socio-technical HMIs may lead to the development of new work environments, which can also have an impact on work organization. While there is still little empirical evidence, the following contribution focuses on the question whether the “manufacturing (or working) life” using enhancement practices pushes the boundaries of HMI and how these effects enable new modes of working in manufacturing. Issues of standardization, acceleration of processes, and order-oriented production become essential for technological innovation in this field. However, these trends tend to lead to a “manufacturing life” in work environments rather than to new modes of work in industry. (shrink)

- Vibrations of light, a sound, a smell, taste, heat and volume transfer energy information (sense) of physical object to consciousness of the person. - Change of physical parameters of object is perceived by the person in time as event. - Event is the information on current of "invisible" process of transfer of energy between cooperating objects. - Process this ordered movement of energy from one object to other object, changing their physical parameters. - Phases of a condition of (...) class='Hi'>processes on the Earth describe laws of dialectics. - The-certain alternation of phases of development of process shows the order of movement of energy incooperating objects (paper pic. N3) - Laws of dialectics it is laws of harmony of succession of events. - Harmony of development of process (movement of energy) is financially(material) perceived by the person as development of event. - A sign on great limit (taiczi) philosophy Dao are graphic expression of laws of dialectics. - Energy of the Sun gives rise to all processes on the Earth. - The INFORMATION is a part of energy reflected or rediated by object written down in memory of the person, a material, space. (shrink)

Open peer commentary on the target article “From Objects to Processes: A Proposal to Rewrite Radical Constructivism” by Siegfried J. Schmidt. Upshot: My suggestion is that the shift from objects to processes can be seen as grounded in the processes of self-generation common to all living organisms. Specifically human cognition is a subsequent evolutionary emergence.

This paper proposes an initial epistemological course related to the notions of life, cognition, and culture from the fundamental elements of the complexity theory and, specifically, related to the notion of self-eco-organization. With these, we pretend to search isomorphic or transverse properties to all these notions; emphasizing the ideas of complexity, autonomy and dependence. El presente trabajo propone un derrotero epistemológico preliminar en torno a las nociones de vida, cognición y cultura, desde la base de algunos elementos de la (...) teoría de la complejidad y en específico, en torno a la noción de auto-eco-organización. Con ellos, se pretende la búsqueda de isomorfismos o propiedades transversales a todas estas nociones, centrándose en la ideas de complejidad, autonomía y dependencia. (shrink)

Based on the fact that the denomination is an institutional system that includes, as components, a certain doctrine, its history, religious and religious practices, church-organizational structure, membership of which identifies and unites this group of believers organizationally, ideologically, morally, dogmatically, psychologically, the confessionalization of religious life is understood.

The essay examines the idea of ―biological space and time‖ found in Evan Thompson‘s Mind in Life and Gilles Deleuze‘s Difference and Repetition. Tracking down this ―new Transcendental Aesthetic‖ intersects new work done on panpsychism. Both Deleuze and Thompson can be fairly said to be biological panpsychists. That‘s what ―Mind in Life‖ means: mind and life are coextensive; life is a sufficient condition for mind. Deleuze is not just a biological panpsychist, however, so we‘ll have to (...) confront full-fledged panpsychism. At the end of the essay we‘ll be able to pose the question whether or not we can supplement Thompson‘s ―Mind in Life‖ position with a ―Mind in Process‖ position and if so, what that supplement means both for his work and for panpsychism. (shrink)

In recent years, an increasing number of theoretical biologists and philosophers of biology have been opposing reductionist research agendas by appealing to the concept of biological autonomy which draws on the older concept of autopoiesis. In my paper, I investigate some of the ontological implications of this approach. The emphasis on autonomy and autopoiesis, together with the associated idea of organisational closure, might evoke the impression that organisms are to be categorised ontologically as substances: ontologically independent, well-individuated, discrete particulars. However, (...) I argue that this is mistaken. Autopoiesis and biological autonomy, properly understood, require a rigorous commitment to a process ontological view of life. (shrink)

This paper evaluates the Hong Kong approach to consent regarding the forgoing of life-sustaining treatment for incompetent elderly patients. It analyzes the contextualized approach in the Hong Kong process-based, consensus-building model, in contrast to other role-based models which emphasize the establishment of a system of formal laws and a clear locus of decisional authority.Without embracing relativism, the paper argues that the Hong Kong model offers an instructive example of how strategic ambiguities can both make good sense within particular cultural (...) context and serve important moral goals. (shrink)

Located at the intersection of philosophy of cognitive science and philosophy of biology, this thesis aims to provide a novel approach to understanding the strong continuity between life and mind. This thesis applies the Free Energy Framework, predictive processing and the conceptual apparatus from ecological psychology to reveal different manners in which the organizational processes and principles underlying life have been enriched so as to result in cognitive processes. By using these anticipatory cognitive frameworks this thesis (...) unveils different forms of cognition at work in surprising places and considers how such expressions of cognition are ultimately driven by various forms of environmental complexity. Importing the concepts of affordances, environmental information and perceptual medium from ecological psychology into predictive processing and the Free Energy Framework, an empirically grounded account of cognition as an anticipatory process that allows living systems to adapt to various degrees of uncertainty in their environments at distinct and yet overlapping timescales is argued for. In doing so, this thesis attempts to identify both the explanatory limits of ecological coupling accounts of perception and action, and the possible environmental conditions under which the predictive brain evolved from its decentralized non-neural predecessors as a solution to uncertainty. In contributing to a novel approach to constraining the mind, the various concepts deployed in both philosophy and cognitive science are sharpened, furthering the current debate on what cognition is and how it is related to life. (shrink)

This book examines the process philosophies of Whitehead and others against current discussions of astrobiology, extraterrestrial life, and their engagement by theological and religious systems.

Metaphor is much more than just a linguistic phenomena, argues Gemma Corradi Fiumara, it is in fact the key process by which we construct and develop our ability to understand the world and the people we share it with. Rationality as understood by philosophers has led to a disembodied view of ourselves in which interaction between life and language has been downplayed. By looking at the metaphoric process - in an interpersonal rather than a formal way - its importance (...) in allowing us access to new worlds of experience is revealed. The metaphoric potential in us all exposes us to the world and initiates our involvement in it. (shrink)

In this paper I argue that Deleuze's ‘thinking with’ Whitehead gives access to a range of novel conceptual resources that offer a route out of phenomenology and back to life, a movement beyond intentionality and back to things ‘in their free and wild state’. I lay out four conceptual and methodological markers (there are many more) – creativity, event, prehension, empiricism – that characterise Deleuze's metaphysics and provide a guide for showing how these develop through a sustained becoming with (...) Whitehead. I conclude by looking at Deleuze and Guattari's use of the term most famously associated with Whitehead: the concept of ‘process’. (shrink)

The paper addresses a phenomenological explanation of the processes of meaning-formation that take place in everyday life. Whereas various social sciences have taken a structuralist standpoint and refer to cultural structures that inform and shape the way things are experienced, classical philosophical epistemology, in contrast, has put an emphasis on the individual mind as the active center of meaning-formation. The author argues for a cultural phenomenology that is capable of giving a philosophically satisfying epistemological account of individual experiences (...) that are culturally structured. As a result, meaning-formation processes are viewed as reciprocal enactment of mind and world, creating the qualitative dimension of meaning of human being-in-the-world. (shrink)