Results for 'malignant mesothelioma'

468 found
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  1.  8
    SARS-CoV-2 and Asbestos Exposure: Can Our Experience With Mesothelioma Patients Help Us Understand the Psychological Consequences of COVID-19 and Develop Interventions? [REVIEW]Antonella Granieri, Michela Bonafede, Alessandro Marinaccio, Ivano Iavarone, Daniela Marsili & Isabella Giulia Franzoi - 2020 - Frontiers in Psychology 11.
    Since its emergence, the novel coronavirus disease of 2019 has had enormous physical, social, and psychological impacts worldwide. The aim of this article was to identify elements of our knowledge on asbestos exposure and malignant mesothelioma that can provide insight into the psychological impact of the COVID-19 pandemic and be used to develop adequate interventions. Although the etiology of Covid-19 and MM differs, their psychological impacts have common characteristics: in both diseases, there is a feeling of being exposed (...)
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  2. Asbestos Neglect: Why Asbestos Exposure Deserves Greater Policy Attention.Thomas Douglas & Laura Van den Borre - 2019 - Health Policy 123 (5):516-519.
    While many public health threats are now widely appreciated by the public, the risks from asbestos exposure remain poorly understood, even in high-risk groups. This article makes the case that asbestos exposure is an important, ongoing global health threat, and argues for greater policy efforts to raise awareness of this threat. It also proposes the extension of asbestos bans to developing countries and increased public subsidies for asbestos testing and abatement.
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  3.  26
    Malign and benign neglect: a local food system and the myth of sustainable redevelopment in Appalachia Ohio.Angela M. Chapman & Harold A. Perkins - 2020 - Agriculture and Human Values 37 (1):113-127.
    Local food systems seem virtuous in the larger context of the neoliberalization of global food systems and increasing food insecurity. However, local food systems are critiqued for reproducing neoliberalism when they prioritize niche-market consumerism over enhancing access for poor people. Advocates, in contrast, insist local food systems contribute to an equitable political economy of food if they are place-based and inclusive. Local food systems must not, according to them, be condemned monolithically in light of their neoliberal tendencies, but evaluated instead (...)
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  4.  14
    The Malignant Demon and Mathematics.Walter H. O'briant - 1978 - Studia Leibnitiana 10 (1):101 - 112.
    Dieser Artikel ist eine Antwort auf Dr. J. G. Cottinghams The Role of the Malignant Demon. Ich stelle die folgenden Behauptungen von Dr. Cottingham in Frage: 1) daß die Sätze der Logik und Mathematik in der ersten Meditation nur nebenbei behandelt werden; 2) daß Descartes glaubt, daß die Sätze der Mathematik keine Existenzbedeutung haben; 3) daß „parum curant“ bedeutet „sie kümmern sich wenig um“; 4) daß die Hypothese des bösen Dämons nur eine subsidiäre Rolle spiele.
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  5.  34
    Going malignant: the hypoxia‐cancer connection in the prostate.P. W. Hochachka, J. L. Rupert, L. Goldenberg, M. Gleave & P. Kozlowski - 2002 - Bioessays 24 (8):749-757.
    The metabolic organization of both normal and malignant prostate cellular phenotypes involves some unusual and surprising features. In particular, both conditions exhibit ratios of NADH/NAD+ and NADPH/NADP+ charactersitic of high oxidative states despite a chronic shortage of O2 in both conditions. In this paper, we observe that, in prostate cancer cells, the oxidizing power of the fatty acid synthesis (FAS) pathway is so large that redox is stabilized more favorably (more oxidized) than in normal prostate cells. This FAS‐facilitated redox (...)
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  6.  34
    Much Maligned Monsters, History of European Reactions to Indian Art.Donald F. Lach & Partha Mitter - 1979 - Journal of the American Oriental Society 99 (2):356.
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  7.  38
    The Malignancy of Evil: Witnessing Violence beyond Justice.James Hatley - 2003 - Studies in Practical Philosophy 3 (2):84-106.
  8.  39
    Malign Neglect: Assessing Older Women’s Health Care Experiences in Prison.Ronald Aday & Lori Farney - 2014 - Journal of Bioethical Inquiry 11 (3):359-372.
    The problem of providing mandated medical care has become commonplace as correctional systems in the United States struggle to manage unprecedented increases in its aging prison population. This study explores older incarcerated women’s perceptions of prison health care policies and their day-to-day survival experiences. Aggregate data obtained from a sample of 327 older women residing in prison facilities in five Southern states were used to identify a baseline of health conditions and needs for this vulnerable group. With an average of (...)
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  9. Malignant" middle cerebral artery infarction.Stephen Honeybul, Volker Puetz & Lars-Peder Pallesen - 2020 - In Ethics in neurosurgical practice. New York, NY: Cambridge University Press.
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  10.  4
    Malign masters: Gentile, Heidegger, Lukács, Wittgenstein: philosophy and politics in the twentieth century.Harry Redner - 1997 - New York: St. Martin's Press.
    A politically oriented study of the thought of the founders of the main schools of contemporary academic philosophy, those which dominate nearly all universities throughout the world. It concentrates on four key masters: Wittgenstein, who founded both Logical Positivism and the so-called Common Language or Analytic school; Heidegger, the acknowledged master of Hermeneutic Philosophy or the so-called Continental school; Lukacs, the founder of Hegelian Marxism and the leading Communist philosopher of the Soviet period; and, finally, the now lesser-known Gentile, the (...)
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  11.  20
    How germline genes promote malignancy in cancer cells.Jan Willem Bruggeman, Jan Koster, Ans M. M. van Pelt, Dave Speijer & Geert Hamer - 2023 - Bioessays 45 (1):2200112.
    Cancers often express hundreds of genes otherwise specific to germ cells, the germline/cancer (GC) genes. Here, we present and discuss the hypothesis that activation of a “germline program” promotes cancer cell malignancy. We do so by proposing four hallmark processes of the germline: meiosis, epigenetic plasticity, migration, and metabolic plasticity. Together, these hallmarks enable replicative immortality of germ cells as well as cancer cells. Especially meiotic genes are frequently expressed in cancer, implying that genes unique to meiosis may play a (...)
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  12.  7
    Maligned for mathematics: Sir Thomas Urquhart and his Trissotetras.Robert Haas - 2019 - Annals of Science 76 (2):113-156.
    Thomas Urquhart (1611–1660), celebrated for his English translation of Rabelais’ Gargantua et Pantagruel, has earned some notoriety for his eccentric, putatively incomprehensible early book on trigonometry The Trissotetras (1645). The Trissotetras was too impractical to succeed in its own day as a textbook, since it lacked both trigonometric tables and sample calculations. But its current bad reputation is based on literary authors’ amplifications of the verdict prefaced to its 19th century reprinting by one mathematician, William Wallace, who lacked the background (...)
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  13.  19
    Malignant: How Bad Policy and Bad Evidence Harm People with Cancer, by Vinay Prasad, Baltimore, Maryland, Johns Hopkins University Press, 2020.Anya Plutynski - 2022 - Cambridge Quarterly of Healthcare Ethics 31 (2):275-278.
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  14. Epistemic circularity: Malignant and benign.Michael Bergmann - 2004 - Philosophy and Phenomenological Research 69 (3):709–727.
    * Editor’s Note: This paper won the Young Epistemologist Prize for the Rutgers Epistemology conference held in 2003.
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  15.  11
    Malignant yet Benign: The Political Economy of a Skin Cancer Diagnosis in Colombia.Camilo Sanz - 2020 - Science, Technology, and Human Values 45 (1):112-137.
    This paper is about the ontology of a cancer diagnosis at high-end hospitals in Colombia. Drawing on a seventeen-month ethnographic fieldwork study in this country, it pays attention to how dermatologists, pathologists, and oncologists looked at my partner’s skin during a routine medical checkup and enacted two seemingly contradictory diagnoses: a lethal melanoma and a benign dysplastic nevus—commonly known as mole. Because their differences under the microscope or through dermatology goggles may be subtle, physicians often disagree on what they see. (...)
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  16.  36
    Diversification and progression of malignant tumors.Garth L. Nicolson & Nancy L. Rosenberg - 1987 - Bioessays 6 (5):204-208.
    Tumor‐cell diversification mechanisms insure that malignant neoplasms contain diversified tumor‐cell subpopulations. Because of the instability of tumor cell phenotypes, some malignant cells will evolve with the most favorable properties for their progression to highly metastatic cells. The rates of cellular phenotypic diversification vary greatly among different tumors, and they are probably modulated, in part, by genetic and chromosome defects and by epigenetic events that may vary widely depending upon the nature of the tumor cells and their microenvironments. As (...)
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  17.  5
    Malignant: Medical Ethicists Confront Cancer.Rebecca Dresser (ed.) - 2012 - Oup Usa.
    This book tells the stories of seven people with a distinct perspective on cancer. Experts on medical ethics, personal experience showed them how little they knew about the real world of serious illness. In this book, they describe cancer's teachings on ethics, medicine, and the experience of illness.
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  18.  15
    Malign neglect.Hugh Lloyd-Jones - 1984 - Minerva 22 (3-4):405-409.
  19.  17
    (1 other version)Malignant Normality and the Dilemma of Resistance: Honoring Minima Moralia.Shierry Weber Nicholsen - 2021 - Krisis 41 (2):93-94.
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  20.  33
    The Malignant Object: Thoughts on Public Sculpture.Douglas Stalker & Clark Glymour - unknown
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  21.  31
    Paediatric deep brain stimulation: ethical considerations in malignant Tourette syndrome.Rosemary T. Behmer Hansen, Arjun Dubey, Cynthia Smith, Patrick J. Henry & Antonios Mammis - 2020 - Journal of Medical Ethics 46 (10):668-673.
    Gilles de la Tourette syndrome (TS) is a childhood neuropsychiatric disorder characterised by the presence of motor and vocal tics. Patients with malignant TS experience severe disease sequelae; risking morbidity and mortality due to tics, self-harm, psychiatric comorbidities and suicide. By definition, those cases termed ‘malignant’ are refractory to all conventional psychiatric and pharmacological regimens. In these instances, deep brain stimulation (DBS) may be efficacious. Current 2015 guidelines recommend a 6-month period absent of suicidal ideation before DBS is (...)
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  22.  88
    Aristotle's much maligned megalopsychos.Howard J. Curzer - 1991 - Australasian Journal of Philosophy 69 (2):131 – 151.
  23.  22
    The Role of the Malignant Demon.J. G. Cottingham - 1976 - Studia Leibnitiana 8 (2):257 - 264.
    Descartes nimmt in Anspruch, daß sein Argument des Deus malignus über die Einwände der Skeptiker hinausgehe. Was fügt es dem Traumargument hinzu? Die verbreitete Ansicht, der Dämon stelle die Erkenntnis mathematischer und logischer Wahrheiten in Frage, wird im folgenden diskutiert und zurückgewiesen. Die richtige Interpretation lautet: Die Annahme des Dämons unterstützt den Skeptizismus und verstärkt die Zweifel an der Existenz äußerer Objekte. Es werden drei Einwände gegen diese Interpretation erörtert und zurückgewiesen. Eine andere Auffassung vertritt Frankfurt: Die Rolle des Traumarguments (...)
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  24. Books etcetera-malignant sadness: The anatomy of depression.Mark S. Bauer - 1999 - Trends in Cognitive Sciences 3 (11):443.
  25. La Nature maligne dans le dualisme cathare du XIIIe siècle, de l'inégalité des deux principes.René Nelli - 1969 - Carcassonne,: Éditions de la revue "Folklore,".
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  26.  15
    Tumor‐induced solid stress activates β‐catenin signaling to drive malignant behavior in normal, tumor‐adjacent cells.Guanqing Ou & Valerie Marie Weaver - 2015 - Bioessays 37 (12):1293-1297.
    Recent work by Fernández‐Sánchez and coworkers examining the impact of applied pressure on the malignant phenotype of murine colon tissue in vivo revealed that mechanical perturbations can drive malignant behavior in genetically normal cells. Their findings build upon an existing understanding of how the mechanical cues experienced by cells within a tissue become progressively modified as the tissue transforms. Using magnetically stimulated ultra‐magnetic liposomes to mimic tumor growth ‐induced solid stress, Fernández‐Sánchez and coworkers were able to stimulate β‐catenin (...)
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  27.  34
    Convergent Expert Views on Decision-Making for Decompressive Craniectomy in Malignant MCA Syndrome.Daniel Mendelsohn, Charles S. Haw & Judy Illes - 2014 - Neuroethics 7 (3):365-372.
    Background and Purpose The decision to perform decompressive craniectomy for patients with malignant MCA syndrome can be ethically complex. We investigated factors that clinicians consider in this decision-making process. Methods A survey including clinical vignettes and attitudes questions surrounding the use of hemicraniectomy in malignant MCA syndrome was distributed to 203 neurosurgeons, neurologists, staff and residents, and nurses and allied health members specializing in the care of neurological patients. These were practicing health care providers situated in an urban (...)
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  28.  66
    Opioids for chronic pain of non-malignant origin—Caring or crippling.Robert G. Large & Stephan A. Schug - 1995 - Health Care Analysis 3 (1):5-11.
    Pain management has improved in the past few decades. Opioid analgesics have become the mainstay in the treatment of cancer pain whilst inter-disciplinary pain management programmes are the generally accepted approach to chronic pain of non-malignant origin. Recently some pain specialists have advocated the use of opioids in the long-term management of non-cancer pain. This has raised some fundamental questions about the purpose of pain management. Is it best to opt for maximum pain relief and comfort, or should one (...)
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  29. Memes and the malign user illusion.S. Blackmore - 2000 - Consciousness and Cognition 9 (2):S49 - S49.
  30.  24
    Abandoned Communities: The Malignant Social Consequences of Modern Technology on Communities.Melvin W. Barber - 2006 - Journal of Evolution and Technology 15 (1):37-50.
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  31. Meinong's much maligned modal moment.K. A. - 2002 - Grazer Philosophische Studien 64 (1):95-118.
    Russell's objections to object-theory have been refuted by the proofs of the consistency of Meinong's system given by various writers. These proofs exploit technical distinctions that Meinong apparently uses very little if at all. Instead, Meinong introduces a theoretical postulate called the modal moment. I describe this postulate and its place in Meinong's system, and I argue that it has been much under-rated by Meinong's logician expositors.
     
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  32.  26
    Atlas the Malignant.A. Macc Armstrong - 1949 - The Classical Review 63 (02):50-.
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  33.  33
    From Ritalin to Malignant Teaching—The Fuzzy Borders of Neuroenhancement.Alex Mauron & Samia Hurst - 2010 - American Journal of Bioethics Neuroscience 1 (1):31-33.
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  34.  18
    The Management of Terminal Malignant Disease.Robin Pugsley - 1986 - Journal of Medical Ethics 12 (1):48-48.
  35. On some much maligned remarks of Wittgenstein on gödel.Charles Sayward - 2001 - Philosophical Investigations 24 (3):262–270.
    In "Remarks on the Foundations of Mathematics" Wittgenstein discusses an argument that goes from Gödel’s incompleteness result to the conclusion that some truths of mathematics are unprovable. Wittgenstein takes issue with this argument. Wittgenstein’s remarks in this connection have received very negative reaction from some very prominent people, for example, Gödel and Dummett. The paper is a defense of what Wittgenstein has to say about the argument in question.
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  36.  5
    The Much-Maligned Cliche Strikes Back.William R. Brown - 1994 - Inquiry: Critical Thinking Across the Disciplines 14 (1):89-93.
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  37.  13
    Reconditis: a malignant variety of obscurantism associated with pathological deficit of common sense.William M. Landau - 1998 - Perspectives in Biology and Medicine 42 (2):220-224.
  38. «Delle cagioni delle febbri maligne» di GA Borelli. Una lettura contestuale.Oreste Trabucco - 2000 - Giornale Critico Della Filosofia Italiana 20 (2-3):236-280.
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  39.  34
    The Much-Maligned and Misunderstood Eternal Consciousness.Colin Tyler - 2003 - Bradley Studies 9 (2):126-138.
    The primary purpose of this paper is to defend three controversial claims that arise out of T.H. Green’s arguments in the first two books of the Prolegomena to Ethics. The first claim—which I defend in §1—is that one should not try to separate the aspects of Green’s metaphysical theory that are set out in book one of the Prolegomena from the theory of the will he developed in book two. The second claim—defended in §2—is that it is possible for an (...)
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  40.  9
    Malignant by Vinay Prasad Oncology’s Leading Gadfly Authors. [REVIEW]Benjamin Chin-Yee - 2021 - Philosophy of Medicine 2 (1).
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  41.  14
    Re‐expression of major histocompatibility complex (UMHC) class I molecules on malignant tumor cells and its effect on host‐tumor interaction.Kam M. Hui - 1989 - Bioessays 11 (1):22-26.
    The expression of products encoded by the major histocompatibility complex (MHC) on tumor cells has recently been studied extensively. It has been found that many malignant tumor cells have their MHC antigens ‘switched‐off’ but that these antigens are re‐expressed following DNA‐mediated gene transfer, with increased tumor immunogenicity as a result and the consequence that these ‘transformed’ tumor cells are rejected in vivo.: This review will discuss approaches that have been taken to induce strong tumor‐specific immunity by the manipulation of (...)
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  42.  28
    The SCL/TAL1 gene: Roles in normal and malignant haematopoiesis.Lorraine Robb & C. Glenn Begley - 1997 - Bioessays 19 (7):607-613.
    SCL (TAL1/TCL5) is a member of the helix‐loop‐helix family of transcription factors. Originally identified because of its involvement in a tumour‐specific chromosomal translocation, overexpression of the SCL gene is the most common molecular abnormality found in human T cell leukaemia. Transgenic models have now formally demonstrated that overexpression of SCL within the T cell lineage is capable of causing malignant transformation. Gene targeting experiments have revealed that the SCL gene is crucial for the development of primitive haematopoiesis in the (...)
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  43.  86
    (1 other version)Jealousy Revisited: Recent Philosophical Work on a Maligned Emotion.Kristján Kristjánsson - 2015 - Ethical Theory and Moral Practice (3):1-14.
    Taking as its starting point a previous work by the author which reviewed early philosophical sources on jealousy and proposed both a conceptual and moral account of this much-maligned emotion, the present article reviews the relevant philosophical literature from the last decade or so. Most noticeable is how scarce those sources still are. Special attention is given, however, to a new conceptual model proposed by Purshouse and Fredericks which rejects the standard architectonic of jealousy as a three-party compound emotion. While (...)
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  44.  17
    Hybrid Warfare in the Western Balkans: How Structural Vulnerability Attracts Maligned Powers and Hostile Influence.Chris J. Dolan - 2022 - Seeu Review 17 (1):3-25.
    This study analyzes the domestic political, economic, and social conditions in the Western Balkans that provide fertile ground for hostile and maligned actors to manipulate and exploit governments and societies with hybrid war measures, namely cyberattacks and cyber intrusions and disinformation and fake news. It begins with a review and assessment of the prevailing empirical and theoretical literature on hybrid warfare. It then describes two leading empirical indices that measure degrees of permeability and structural vulnerability that elevate or reduce the (...)
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  45.  10
    Europe's Malignant Supplements, I Know. But Nevertheless….Imanol Galfarsoro - 2024 - International Journal of Žižek Studies 18 (1).
    Th is discussion review appeals to a minimal militant comradeship across struggles. Theory is also a struggle, and solidarity is always key. It agrees with Slavoj Žižek’s main argument: the critique of Eurocentrism cannot sustain itself without acknowledging the positive influence of the Enlightenment radical tradition. It also underlines that particular emancipatory projects set against universalism fail to properly problematise political subjectivity. This is not to coalesce with certain Western/European metropolitan intellectual and political inclinations, not least in the Left, particularly (...)
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  46.  17
    Design and analysis of quantum powered support vector machines for malignant breast cancer diagnosis.Garima Aggarwal, Ishika Dhall & Shubham Vashisth - 2021 - Journal of Intelligent Systems 30 (1):998-1013.
    The rapid pace of development over the last few decades in the domain of machine learning mirrors the advances made in the field of quantum computing. It is natural to ask whether the conventional machine learning algorithms could be optimized using the present-day noisy intermediate-scale quantum technology. There are certain computational limitations while training a machine learning model on a classical computer. Using quantum computation, it is possible to surpass these limitations and carry out such calculations in an optimized manner. (...)
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  47. A Modern Malignant Demon? Hume's Scepticism with Regard to Reason (Partly) Vindicated.George Couvalis - 2011 - In Craig Taylor & Stephen Buckle (eds.), Hume and the Enlightenment. Pickering & Chatto Publishing. pp. 105-115.
  48.  40
    Gene therapy for neurodegenerative disorders and malignant brain tumors.Lan Chiang, Eric P. Flores, Dennis Y. Wen, Walter A. Hall & Walter C. Low - 1995 - Behavioral and Brain Sciences 18 (1):52-53.
    Gene therapy approaches have great promise in the treatment of neurodegenerative disorders and malignant brain tumors. Neuwelt et al. review available viral-mediated gene therapy methods and their blood-brain-barrier (BBB) disruption delivery technique, briefly mentioning nonviral mediated gene therapy methods. This commentary discussed the BBB disruption delivery technique, viral and nonviral mediated gene therapy approaches to Parkinson's disease, and the potential use of antisense oligo to suppress malignant brain tumors.
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  49.  60
    Meinong’s much maligned modal moment.Andrew Kenneth Jorgensen - 2002 - Grazer Philosophische Studien 64 (1):95-118.
    Russell's objections to object-theory have been refuted by the proofs of the consistency of Meinong's system given by various writers. These proofs exploit technical distinctions that Meinong apparently uses very little if at all. Instead, Meinong introduces a theoretical postulate called the modal moment. I describe this postulate and its place in Meinong's system, and I argue that it has been much under-rated by Meinong's logician expositors.
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  50.  25
    Anoxia, wound healing, VL30 elements, and the molecular basis of malignant conversion.Garth R. Anderson & Daniel L. Stoler - 1993 - Bioessays 15 (4):265-272.
    Although VL30 retrotransposable elements have been associated with certain cancers for nearly twenty years, because of their expression in rodent malignancies and recombination into murine sarcoma viruses, their causative role, if any, in cancer has been uncertain and enigmatic. Recent findings suggest loss of normal transcriptional control of specific VL30 element expression may make a critical contribution to tumor progression at a step associated with malignant conversion, by bringing into play a cellular program normally involved in wound healing. This (...)
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