Abstract
Rat performance under a fixed-ratio schedule of food reinforcement was analyzed in terms of distributions of intervals between successive responses (IRTs). A 20-mg/kg IP injection of morphine increased the proportion of longer IRTs without affecting the modal IRT, and increased mean IRT at all positions in the ratio. Fixed-ratio performance returned to baseline during repeated administration of the drug.
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The assistance of Marilyn Schwieder and Michael Ramsey is gratefully acknowledged.
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Gilbert, R.M. Microanalysis of fixed- ratio performance in the rat: Behavioral tolerance to morphine. Bull. Psychon. Soc. 3, 229–231 (1974). https://doi.org/10.3758/BF03333455
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DOI: https://doi.org/10.3758/BF03333455