Abstract
The cases for and against somatic gene therapy, germ-line gene therapy and gene therapy for enhancement are assessed. It is argued that none of these kinds of therapy is inherently wrong, and that an adequate assessment should consist in weighing risks and benefits. On this basis, it is argued that somatic therapy is a promising new kind of treatment that we should welcome; that we have technologies available that make germ-line therapy superfluous, unless we want to engage in enhancement engineering; and that although we should be extremely cautious if we were to engage in enhancement engineering, we cannot categorically rule out that there might be cases in which this kind of therapy should be applied, e.g. if it was the only way of saving millions of lives.
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Holtug, N. Altering humans: The case for and against human gene therapy. Monash Bioethics Review 16, 14 (1997). https://doi.org/10.1007/BF03351207
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DOI: https://doi.org/10.1007/BF03351207