Europe PMC

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy.

Abstract 


New uses of preimplantation genetic diagnosis (PGD) to screen embryos prior to transfer raise ethical, legal, and policy issues that deserve close attention. Extensions for medical purposes, such as to identify susceptibility genes, late onset disease, and human leukocyte antigen (HLA) matching, are usually ethically acceptable. Whether embryo screening for gender, perfect pitch, or other non-medical characteristics are also acceptable depends upon the parental needs served and the harm posed to embryos, children, and society. Speculations about potential future uses of PGD should not prevent otherwise acceptable current uses of PGD.

Free full text 


Logo of jmedethLink to Publisher's site
J Med Ethics. 2003 Aug; 29(4): 213–216.
PMCID: PMC1733767
PMID: 12930852

Extending preimplantation genetic diagnosis: medical and non-medical uses

Full Text

The Full Text of this article is available as a PDF (80K).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Verlinsky Yury, Rechitsky Svetlana, Verlinsky Oleg, Xu Kangu, Schattman Glenn, Masciangelo Christina, Ginberg Norman, Strom Charles, Rosenwaks Zev, Kuliev Anver. Preimplantation diagnosis for p53 tumour suppressor gene mutations. Reprod Biomed Online. 2001;2(2):102–105. [Abstract] [Google Scholar]
  • Verlinsky Y, Rechitsky S, Schoolcraft W, Strom C, Kuliev A. Preimplantation diagnosis for Fanconi anemia combined with HLA matching. JAMA. 2001 Jun 27;285(24):3130–3133. [Abstract] [Google Scholar]
  • Verlinsky Yury, Rechitsky Svetlana, Verlinsky Oleg, Masciangelo Christina, Lederer Kevin, Kuliev Anver. Preimplantation diagnosis for early-onset Alzheimer disease caused by V717L mutation. JAMA. 2002 Feb 27;287(8):1018–1021. [Abstract] [Google Scholar]
  • Simpson Joe Leigh. Celebrating preimplantation genetic diagnosis of p53 mutations in Li-Fraumeni syndrome. Reprod Biomed Online. 2001;3(1):2–3. [Abstract] [Google Scholar]
  • Towner Dena, Loewy Roberta Springer. Ethics of preimplantation diagnosis for a woman destined to develop early-onset Alzheimer disease. JAMA. 2002 Feb 27;287(8):1038–1040. [Abstract] [Google Scholar]
  • Pennings G, Schots R, Liebaers I. Ethical considerations on preimplantation genetic diagnosis for HLA typing to match a future child as a donor of haematopoietic stem cells to a sibling. Hum Reprod. 2002 Mar;17(3):534–538. [Abstract] [Google Scholar]
  • Robertson John A, Kahn Jeffrey P, Wagner John E. Conception to obtain hematopoietic stem cells. Hastings Cent Rep. 2002 May-Jun;32(3):34–40. [Abstract] [Google Scholar]
  • Robertson JA. Preconception gender selection. Am J Bioeth. 2001 Winter;1(1):2–9. [Abstract] [Google Scholar]
  • Robertson John A. Sex selection for gender variety by preimplantation genetic diagnosis. Fertil Steril. 2002 Sep;78(3):463–463. [Abstract] [Google Scholar]
  • Malpani A, Malpani A, Modi D. Preimplantation sex selection for family balancing in India. Hum Reprod. 2002 Jan;17(1):11–12. [Abstract] [Google Scholar]

Articles from Journal of Medical Ethics are provided here courtesy of BMJ Publishing Group

Citations & impact 


Impact metrics

Jump to Citations

Citations of article over time

Article citations


Go to all (19) article citations