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Ab-Ag affinity thresholds in inventory optimization

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Abstract

The role of antibody-antigen affinity and concentrations in adaptive antibody response is analyzed in a framework of probabilistic inventory model for antibody production. Our results indicate significant differences in optimal behaviours of low, moderate and high affinity groups and offer important implications. Interestingly, the involved approach is also of relevance in other production systems. Directions for its applications in industries and information sciences are also presented.

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Authors and Affiliations

  1. Department of Mathematics and School of Biomedical Engineering, Indian Institute of Technology, Powai, 400076, Bombay, India

    Rajani R. Joshi

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  1. Rajani R. Joshi
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This research was supported by a project-grant from the Indian National Science Academy.

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Joshi, R.R. Ab-Ag affinity thresholds in inventory optimization. Acta Biotheor 42, 295–313 (1994). https://doi.org/10.1007/BF00707395

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  • DOI: https://doi.org/10.1007/BF00707395

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