Abstract
The phrase “regenerative medicine” is used so often and for so many different things, with such enthusiasm or worry, and often with a sense that this is something radically new. This paper places studies of regeneration and applications in regenerative medicine into historical perspective. In fact, the first stem cell experiment was carried out in 1907, and many important lines of research have contributed since. This paper explores both what we can learn about the history and what we can learn from the history of regenerative medicine research.
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References
Ascb.org. 2008. American Society for Cell Biology iBioSeminars: Alejandro Sanchez-Alvarado. The problem of regeneration. Part I. A brief (natural) history of regeneration. www.ascb.org. Accessed May 2008.
Billings, S.F. 1971. Concepts of nerve fiber development, 1839–1930. Journal of the History of Biology 4(2): 275–305.
Bodemer, Charles W. 1968. Modern embryology. New York: Holt, Rinehart and Winston.
Brachet, Jean. 1950. Biochemistry of the organism during regeneration. In Chemical embryology (First published in French in 1944; first English translation in 1950). New York: Interscience Publishers.
Evans, M., and M. Kaufman. 1981. Establishment in culture of pluripotential cells from mouse embryos. Nature 292(5819): 154–156.
Hamburger, Viktor. 1988. The heritage of experimental embryology. Hans Spemann and the organizer. New York: Oxford University Press.
Haraway, Donna. 1976. Crystals, fabrics, and fields. Metaphors of organicism in twentieth-century developmental biology. New Haven: Yale University Press.
Harrison, R.G. 1907. Observations on the living development nerve fiber. Anatomical Record 1(5): 116–118.
Harrison, R.G. 1910. The outgrowth of the nerve fiber as a mode of protoplasmic movement. Journal of Experimental Zoology 9(4): 787–846.
Korschelt, Eugen. 1927 and 1931. Regeneration und transplantation (translated into English by Sabine Lichtner Ayed. Edited by Bruce Carlson, Canton MA: Science History Publications, 1990 in vol. I, vol. II parts 1 and 2). Berlin: Gebrüder Bornträger.
Landecker, Hannah. 2004. Building “A new type of body in which to grow a cell”: Tissue culture at the Rockefeller Institute 1910/1914. In Creating a tradition of biomedical research contributions to the history of the Rockefeller University, ed. Darwin H. Stapleton, 135–150. New York: Rockefeller University Press.
Landecker, Hannah. 2007. Culturing life. How cells became technologies. Cambridge: Harvard University Press.
Maienschein, Jane. 1983. Experimental biology in transition: Harrison’s embryology, 1895–1910. Studies in the History of Biology 6: 107–127.
Maienschein, Jane. 1991. Transforming traditions in American biology, 1880–1915. Baltimore: Johns Hopkins University Press.
Maienschein, Jane. 2003. Whose view of life? Embryos, cloning, and stem cells. Cambridge, MA: Harvard University Press.
Martin, G. 1981. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proceedings of the National Academy of Sciences 78(12): 7634–7638.
Mitman, G., and A. Fausto-Sterling. 1992. Whatever happened to Planaria? C. M. Child and the physiology of inheritance. In The right tool for the right job: At work in twentieth-century life sciences, ed. A.E. Clarke, and J.H. Fujimura, 172–197. Princeton: Princeton University Press.
Morgan, Thomas Hunt. 1897. The development of the frog’s egg. An introduction to experimental embryology. New York: Macmillan.
Morgan, Thomas Hunt. 1899. Some problems of regeneration. Marine Biological Laboratory Biological Lectures 1898: 193–207.
Morgan, Thomas Hunt. 1901. Regeneration. New York: Macmillan.
Morgan, Thomas Hunt. 1934. Embryology and genetics. New York: Columbia University Press.
Needham, Joseph. 1942. Biochemistry and morphogenesis. Cambridge: Cambridge University Press.
Ramalho-Santos, M., and H. Willenbring. 2007. On the origin of the term ‘stem cell’. Cell Stem Cell 1(1): 35–38.
Stapleton, Darwin H., ed. 2004. Creating a tradition of biomedical research contributions to the history of the Rockefeller University. New York: Rockefeller University Press.
Sunderland, Mary. 2007. Regeneration and cloning. Paper presented at the workshop on the history of cloning, Max Planck Institute for the History of Science, Berlin, March 2007.
Sunderland, Mary. 2008. Comparing regulative processes to understand development: An examination of John Tyler Bonner’s morphogenesis. Paper presented at the joint atlantic seminar for the history of biology, Princeton, April 2008.
Waddington, C.H. 1956. Principles of development. New York: Macmillan.
Weiss, Paul. 1939. Principles of development. New York: Henry Holt and Company.
Wilson, Edmund Beecher. 1896. The cell in development and heredity. New York: Macmillan.
Wilson, H.V. 1907. On some phenomena of coalescence and regeneration in sponges. The Journal of Experimental Zoology 5(2): 245–258.
Wolpert, Lewis. 1991. Morgan’s ambivalence: A history of gradients and regeneration. In A history of regeneration research milestones in the evolution of a science, ed. C.E. Dinsmore, 201–217. Cambridge: Cambridge University Press.
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Maienschein, J. Regenerative Medicine in Historical Context. Medicine Studies 1, 33–40 (2009). https://doi.org/10.1007/s12376-008-0001-5
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DOI: https://doi.org/10.1007/s12376-008-0001-5