Skip to main content
Log in

Organic Crosstalk: a New Perspective in Medicine

  • Review Articles
  • Published:
Biosemiotics Aims and scope Submit manuscript

Abstract

Organic crosstalk or intercommunication among different organs is an interesting medical concept based on the biosemiotic perspective which considers the organism as a process maintained by the vital information flow between structural plane and biosemiotic plane, both with their different layers of biological complexity. From this point of view the organ is not merely the structure which produces crosstalk but just as much its product. The crosstalk perspective seeks two main goals: to investigate the characteristic serum biosemiotic patterns of pathogenic organic crosstalk in order to achieve early diseases diagnosis, and to learn how to correct it. These achievements could allow physicians to evolve from a medical practice that focuses on misbiosemiotic effects, diagnosing and treating damaged organs, to a medical practice that focuses on misbiosemiotic processes, in this way diagnosing and treating pathogenic organ crosstalk before it culminates in organ damage.

This is a preview of subscription content, log in via an institution to check access.

Access this article

We’re sorry, something doesn't seem to be working properly.

Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  • Barbieri, M. (2014). From biosemiotics to code biology. Biological Theory, 9, 239–249.

    Article  Google Scholar 

  • Barbieri, M. (2018). What is code biology? Biosystems, 164, 1–10.

    Article  CAS  Google Scholar 

  • Barbieri, M. (2020). The semantic theory of language. Biosystems, 190, 104100.

    Article  CAS  Google Scholar 

  • Capalbo, O., Giuliani, S., Ferrero-Fernández, A., Casciato, P., et al. (2019). Kidney-liver pathophysiological crosstalk: Its characteristics and importance. International Urology & Nephroogyl, 51(12), 2203–2207.

    Article  Google Scholar 

  • Colombo, I., Aiello-Battan, F., Elena, R., & Ruiz, A. (2021). Kidney-gut crosstalk in renal disease. Irish Journal of Medical Science, 190, 1205–1212.

    Article  Google Scholar 

  • Domenech, P., Perez, T., Saldarini, A., Uad, P., et al. (2017). Kidney-lung pathophysiological crosstalk: Its characteristics and importance. International Urology & Nephrology, 49(7), 1211–1215.

    Article  CAS  Google Scholar 

  • Donoso, A., Arriagada, D. S., & Cruces, P. R. (2015). Pulmonary-renal crosstalk in the critically ill patient. Revista Chilena De Pediatría, 86(5), 309–317.

    Article  Google Scholar 

  • Lee, S. A., Cozzi, M., Bush, E., & Rabb, H. (2018). Distant organ dysfunction in acute kidney injury: A review. American Journal of Kidney Diseases, 72(6), 846–856.

    Article  Google Scholar 

  • Li, X., Hassoun, H. T., Santora, R., & Rabb, H. (2009). Organ crosstalk: The role of the kidney. Current Opinion in Critical Care, 15(6), 481–487. https://doi.org/10.1097/MCC.0b013e328332f69e

    Article  PubMed  Google Scholar 

  • Mc Phee, S., & Hammer, G. (2010). Pathophysiology of disease. Mc Graw Hill Medical.

    Google Scholar 

  • Musso, C. G. (2019). The epistemology of introspection: The inner key to scientific research. Archivos Argentinos De Pediatría, 117(6), 356–359.

    Google Scholar 

  • Musso, C. G. (2020). Biosemiotic medicine: From an effect-based medicine to a process-based medicine. Archivos Argentinos de Pediatría, 118(5), e449–e453. e449.

    PubMed  Google Scholar 

  • Musso, C. G., & Enz, P. A. (2007). Medical semiotics. Linguistic and communicational principles for medical use. Delhospital ediciones.

    Google Scholar 

  • Musso, C. G., Rosell, C., Gonzalez-Torres, H., Ordonez, J. D., & Aroca-Martinez, G. (2020). Primary prevention for acute kidney injury in ambulatory patients. Postgraduate Medicine, 132(8), 746–748.

    Article  Google Scholar 

  • Porrini, S. (2020). The others. Operational metaphysics in the 20th and 21st centuries. Matrioska.

    Google Scholar 

  • White, L. E., Chaudhary, R., Moore, L. J., Moore, F. A., & Hassoun, H. T. (2011). Surgical sepsis and organ crosstalk: The role of the kidney. Journal of Surgical Research, 167(2), 306–315. https://doi.org/10.1016/j.jss.2010.11.923

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Carlos G. Musso.

Ethics declarations

Conflict of Interest

All the authors declare that they have no conflict of interest.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Musso, C.G., Musso-Enz, V.P., Musso-Enz, G.M. et al. Organic Crosstalk: a New Perspective in Medicine. Biosemiotics 14, 829–837 (2021). https://doi.org/10.1007/s12304-021-09459-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12304-021-09459-3

Keywords

Navigation