Abstract
HIV intervention trials being conducted in developing countries continue to raise questions of ethics in clinical research. Most recently these questions have arisen because of a prospective study reporting the rate of transmission in discordant couples that was conducted in Uganda. The study raises serious questions about the minimum ethical standards required for this kind of research and the responsibilities of the researchers. We re-examine that research particularly focusing on issues of informed consent and duty of care, and place this trial in the context of the broader debate.
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Reidpath, D., Allotey, P. & Thomas, J. Ethics and trials in developing countries: Researchers and responsibility. Monash Bioethics Review 19, S53–S64 (2000). https://doi.org/10.1007/BF03351240
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DOI: https://doi.org/10.1007/BF03351240