Phospholipiid structure and states of lipid peroxidation of erythrocyte membranes in newborn from mothers with hestosis combined with chronic pyelonephritis

Abstract

A complete clinical and laboratory examination of 69 newborns was carried out, of which 23 children were born from physiologically healthy mothers, 20 children were born from mothers who had only preeclampsia during pregnancy, and 26 children, born from mothers with the 2nd and 3rd degree of preeclampsia and chronic pyelonephritis.Having considered the nature of changes in lipid peroxidation, the phospholipid spectrum of the lipid bilayer of erythrocyte membranes in healthy newborns and those born from mothers with pure combined preeclampsia, it should be noted that there are the most profound changes in the structure of cytomembranes in newborns whose gestation proceeded against the background of preeclampsia, combined with chronic pyelonephritis, about as evidenced by the accumulation of lysoforms of phospholipids, the end products of lipid peroxidation.

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