BENDing with Polycomb in pluripotency and cancer

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Bioessays 45 (8):2300046 (2023)
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Abstract

Three recent publications on BEND3 firmly establish its role as a novel sequence‐specific transcription factor that is essential for PRC2 recruitment and maintenance of pluripotency. Here, we briefly review our current understanding of the BEND3‐PRC2 axis in the regulation of pluripotency and also explore the possibility of a similar connection in cancer.

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10.1002/bies.202300046

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