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Position effect variegation in Drosophila: Towards a genetics of chromatin assembly
Bioessays 11 (1):14-17 (1989)
Abstract
The formation of a highly condensed chromosome structure (heterochromatin) in a region of a eukaryotic chromosome can inactivate the genes within that region. Genetic studies using the fruitfly Drosophila melanogaster have identified several essential genes which influence the formation of heterochromatin. My purpose in this review is to summarize some recent work on the genetics of heterochromatin assembly in Drosophila and a recent model for how chromosomal proteins may interact to form a heterochromatic structure.My notes
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Citations of this work
Position effect variegation and chromatin proteins.Gunter Reute & Pierre Spierer - 1992 - Bioessays 14 (9):605-612.
Dosage‐dependent modification of position‐effect variegation in Drosophla.Steven Henikoff - 1996 - Bioessays 18 (5):401-409.
Position effects, methylation and inherited epigenetic states.A. S. Wilkins - 1990 - Bioessays 12 (8):385-386.
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