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The metastatic cancer cell cortex: An adaptation to enhance robust cell division in novel environments?
Bioessays 34 (12):1017-1020 (2012)
Abstract
Graphical AbstractTo metastasize, cancer cells must be able to complete cell division in environments very different from their tissue of origin. We suggest that mitotic cell rounding, aided by several actin-regulatory oncogenes, may facilitate this process in a robust, context-independent manner.My notes
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