Uses of vaccinia virus as a vector for the production of live recombinant vaccines

&
Bioessays 1 (3):120-124 (1984)
  Copy   BIBTEX

Abstract

Vaccinia virus, the world's oldest vaccine, was used originally for the eradication of smallpox. It is now being genetically engineered to create new live vaccines for use against other infectious agents of medical and veterinary importance. Genes coding for antigens of several pathogens have been linked to vaccinia virus transcriptional regulatory signals and inserted into the vaccinia virus genome. The resultant recombinant viruses are infectious, express the foreign gene, stimulate specific immune responses in vaccinated animals and can protect against disease caused by the corresponding pathogen.

Categories

Keywords

Reprint years

DOI

10.1002/bies.950010308

Links

PhilArchive



    Upload a copy of this work     Papers currently archived: 91,853

External links

Setup an account with your affiliations in order to access resources via your University's proxy server

Through your library

My notes

Similar books and articles

The use of vaccinia virus for the construction of recombinant vaccines.Antonia Piccini & Enzo Paoletti - 1986 - Bioessays 5 (6):248-252.
Gene replacement therapy in the central nervous system: Viral vector-mediated therapy of global neurodegenerative disease.Edward A. Neuwelt, Michael A. Pagel, Alfred Geller & Leslie L. Muldoon - 1995 - Behavioral and Brain Sciences 18 (1):1-9.
Between Bacteriology and Virology: The Development of Typhus Vaccines Between the First and Second World Wars.Paul Weindling - 1995 - History and Philosophy of the Life Sciences 17 (1):81 - 90.
Factory, Hazard, and Contamination: The Use of Metaphor in the Commercialization of Recombinant DNA.Jeannette A. Colyvas - 2007 - Minerva 45 (2):143-159.
Ethically compromised vaccines in Australia.Kerri Anne Brussen - 2012 - Chisholm Health Ethics Bulletin 17 (3):1.
Ethically compromised vaccines and catholic teaching.Kevin McGovern & Brussen - 2011 - Chisholm Health Ethics Bulletin 17 (2):1.
Angela N.H. Creager, The Life of a Virus: Tobacco Mosaic Virus as an Experimental Model, 1930–1965. Chicago: University of Chicago Press, 2002. [REVIEW]Rachel Allyson Ankeny - 2003 - Metascience 12 (3):341-344.
Women's views about participating in research while pregnant.A. D. Lyerly, E. E. Namey, B. Gray, G. Swamy & R. R. Faden - 2012 - IRB: Ethics & Human Research 34 (4):1-8.
Challenging the Production of Vaccines for a Future Influenza Pandemic.Benjamin Capps & Tamra Lysagh - 2013 - Asian Bioethics Review 5 (2):110-130.
Strategies of Research For a Vaccine Against AIDS.Max Essex - 1995 - History and Philosophy of the Life Sciences 17 (1):141 - 149.
Regulation of Recombinant DNA Research.Susan G. Hadden - 1978 - In John Richards (ed.), Recombinant DNA: science, ethics, and politics. New York: Academic Press. pp. 207.
A Legal Perspective on Recombinant DNA Research.Harold Green - 1978 - In John Richards (ed.), Recombinant DNA: science, ethics, and politics. New York: Academic Press. pp. 193.
The Development and Utilization of Recombinant DNA Technology.Sidney R. Kushner - 1978 - In John Richards (ed.), Recombinant DNA: science, ethics, and politics. New York: Academic Press. pp. 35--53.
Should Recombinant DNA Research be Regulated?Tom L. Beauchamp - 1978 - In John Richards (ed.), Recombinant DNA: science, ethics, and politics. New York: Academic Press. pp. 225.

Analytics

Added to PP
2014-01-19

Downloads
13 (#1,036,484)

6 months
4 (#790,339)

Historical graph of downloads
How can I increase my downloads?

Citations of this work

No citations found.

Add more citations

References found in this work

No references found.

Add more references