fMRI and its interpretations: an illustration on directional selectivity in area V5/MT


fMRI is a tool to study brain function noninvasively that can reliably identify sites of neural involvement for a given task. However, to what extent can fMRI signals be related to measures obtained in electrophysiology? Can the blood-oxygen-level-dependent signal be interpreted as spatially pooled spiking activity? Here we combine knowledge from neurovascular coupling, functional imaging and neurophysiology to discuss whether fMRI has succeeded in demonstrating one of the most established functional properties in the visual brain, namely directional selectivity in the motion-processing region V5/ MT+. We also discuss differences of fMRI and electrophysiology in their sensitivity to distinct physiological processes. We conclude that fMRI constitutes a complement, not a poor-resolution substitute, to invasive techniques, and that it deserves interpretations that acknowledge its stand as a separate signal.



    Upload a copy of this work     Papers currently archived: 92,323

External links

  • This entry has no external links. Add one.
Setup an account with your affiliations in order to access resources via your University's proxy server

Through your library

  • Only published works are available at libraries.

Similar books and articles

Images are not the evidence in neuroimaging.Colin Klein - 2010 - British Journal for the Philosophy of Science 61 (2):265-278.
Philosophical issues in neuroimaging.Colin Klein - 2010 - Philosophy Compass 5 (2):186-198.
Studying the mind from the inside out.Dan Lloyd - 2002 - Brain and Mind 3 (1):243-59.


Added to PP

29 (#554,418)

6 months
1 (#1,478,551)

Historical graph of downloads
How can I increase my downloads?