Molecular biology of plasminogen activators and recombinant DNA progress

Bioessays 1 (4):168-173 (1984)
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Abstract

Plasminogen activators are enzymes with multiple roles. They play vital parts in maintaining the functional integrity of the vascular system and they are also involved in processes of tissue reorganization. In this review, the molecular properties of these enzymes that make them ideal targets for genetic and biochemical engineering to satisfy a potential therapeutic role are described.

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