Abstract
The field of semiotics is described as a general study of knowing. Knowing in a broad sense as a process that assumes (and includes) at least memory (together with heredity), anticipation, communication, meaningful information, and needs, is a distinctive feature of living systems. Sciences are distinguished accordingly into 'phi-sciences' (that use physicalist methodology) and 'sigma-sciences' (that use semiotic methodology). Jesper Hoffmeyer’s book Biosemiotics is viewed as an inquiry into the sigma-scientific approach to living systems.