Advances in Quantum Chemistry 82:253-300 (2020)

Authors
Danko D. Georgiev
Institute For Advanced Study, Varna
Abstract
The essential biological processes that sustain life are catalyzed by protein nano-engines, which maintain living systems in far-from-equilibrium ordered states. To investigate energetic processes in proteins, we have analyzed the system of generalized Davydov equations that govern the quantum dynamics of multiple amide I exciton quanta propagating along the hydrogen-bonded peptide groups in α-helices. Computational simulations have confirmed the generation of moving Davydov solitons by applied pulses of amide I energy for protein α-helices of varying length. The stability and mobility of these solitons depended on the uniformity of dipole-dipole coupling between amide I oscillators, and the isotropy of the exciton-phonon interaction. Davydov solitons were also able to quantum tunnel through massive barriers, or to quantum interfere at collision sites. The results presented here support a nontrivial role of quantum effects in biological systems that lies beyond the mechanistic support of covalent bonds as binding agents of macromolecular structures. Quantum tunneling and interference of Davydov solitons provide catalytically active macromolecular protein complexes with a physical mechanism allowing highly efficient transport, delivery, and utilization of free energy, besides the evolutionary mandate of biological order that supports the existence of such genuine quantum phenomena, and may indeed demarcate the quantum boundaries of life.
Keywords Biological order  Davydov soliton  Protein α-helix  Quantum interference  Quantum tunneling
Categories (categorize this paper)
Options
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

PhilArchive copy

 PhilArchive page | Other versions
External links

Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library

References found in this work BETA

Add more references

Citations of this work BETA

Quantum Information Theoretic Approach to the Mind–Brain Problem.Danko D. Georgiev - 2020 - Progress in Biophysics and Molecular Biology 158:16-32.

Add more citations

Similar books and articles

Launching of Davydov Solitons in Protein Α-Helix Spines.Danko D. Georgiev & James F. Glazebrook - 2020 - Physica E: Low-Dimensional Systems and Nanostructures 124:114332.
Magic Without Magic: Meaning of Quantum Brain Dynamics.Marj Jibu & Kunio Yasue - 1997 - Journal of Mind and Behavior 18 (2-3):205-228.
Quantum Phenomena in a Classical Model.Vieri Benci - 1999 - Foundations of Physics 29 (1):1-28.

Analytics

Added to PP index
2020-12-03

Total views
48 ( #236,079 of 2,507,555 )

Recent downloads (6 months)
21 ( #41,955 of 2,507,555 )

How can I increase my downloads?

Downloads

My notes