Biomarkers as Surrogate Endpoints: Ongoing Opportunities for Validation

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Journal of Law, Medicine and Ethics 47 (3):393-395 (2019)
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Abstract

Surrogate endpoints are a common application of biomarkers to estimate clinical benefit in clinical trials, despite questions about reliability. This article discusses ongoing opportunities for their validation, in the context of a regulatory environment in which they are increasingly championed.

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10.1177/1073110519876170

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