Monash Bioethics Review 32 (1-2):63-85 (2014)

Authors
Annette Rid
University of Zürich
Abstract
One of the fundamental ethical concerns about biomedical research is that it frequently exposes participants to risks for the benefit of others. To protect participants’ rights and interests in this context, research regulations and guidelines set out a mix of substantive and procedural requirements for research involving humans. Risk thresholds play an important role in formulating both types of requirements. First, risk thresholds serve to set upper risk limits in certain types of research. Second, risk thresholds serve to demarcate risk categories that streamline risk-adapted systems of ethical oversight. But although risk thresholds play such an important role in research governance, there is a need both to better define the existing risk thresholds and to delineate new thresholds in order to develop more risk-adapted systems of research oversight. The present paper examines the existing minimal risk threshold and the surrounding debates with the goal of deriving a systematic approach to setting thresholds of research risk.
Keywords Minimal risk   Research ethics   Research ethics review   Research regulation   Risk-adapted regulation   Risk category   Risk threshold   Subject protection
Categories No categories specified
(categorize this paper)
ISBN(s)
DOI 10.1007/s40592-014-0007-6
Options
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

PhilArchive copy


Upload a copy of this paper     Check publisher's policy     Papers currently archived: 51,554
External links

Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library

References found in this work BETA

No references found.

Add more references

Citations of this work BETA

The Upper Limits of Pain and Suffering in Animal Research.Tom L. Beauchamp & David B. Morton - 2015 - Cambridge Quarterly of Healthcare Ethics 24 (4):431-447.

Add more citations

Similar books and articles

On the Minimal Risk Threshold in Research With Children.Ariella Binik - 2014 - American Journal of Bioethics 14 (9):3-12.
Can Informed Consent to Research Be Adapted to Risk?Danielle Bromwich & Annette Rid - 2015 - Journal of Medical Ethics 41 (7):521-528.
Minimal Risk in Research Involving Pregnant Women and Fetuses.Carson Strong - 2011 - Journal of Law, Medicine and Ethics 39 (3):529-538.
Why the Debate Over Minimal Risk Needs to Be Reconsidered.Ariella Binik & Charles Weijer - 2014 - Journal of Medicine and Philosophy 39 (4):387-405.
The Concept of Risk and Responsible Conduct of Research.Eugenijus Gefenas - 2006 - Science and Engineering Ethics 12 (1):75-83.
De Minimis Risk: A Proposal for a New Category of Research Risk.Abraham Schwab - 2011 - American Journal of Bioethics 11 (11):1-7.
"Making More Sense of" Minimal Risk".Deborah Barnbaum - 2002 - IRB: Ethics & Human Research 24 (3):10-13.
Minimal Risk as an International Ethical Standard in Research.Loretta M. Kopelman - 2004 - Journal of Medicine and Philosophy 29 (3):351 – 378.

Analytics

Added to PP index
2018-06-30

Total views
10 ( #804,729 of 2,331,151 )

Recent downloads (6 months)
1 ( #589,978 of 2,331,151 )

How can I increase my downloads?

Downloads

My notes