This text explores how we understand living and other complex systems. The conventional basis of understanding rests on abstract general theories, but this book proposes conceptual continuity as a new means of comparing systems of divergent complexity and resolving problems in complex systems.

It has been tacitly assumed that certain fundamental “laws” of science have the same meaning and significance in the different scientific disciplines. Outside of quantum physics the law of causality was regarded as such a concept which was most generally applicable in the description of the systems of nature. However, the role of causality in recent research in biology seems not quite clear. There an explanation of the specific properties of biological systems does not assume the form of a simple (...) law such as a mathematical expression relating different states of one and the same system. Rather it is attempted to show how the properties of the system as a whole are established by the specific interaction of the parts of the system. (shrink)

It may seem trivial to state that one of the major trends in biological investigation consists in an attempt to explain the structural and functional aspects of living matter in chemical terms, in an effort to obtain insight into the equivalent of macroscopic phenomena on the molecular level. I am sure you are aware of, and this meeting of the Association has brought ample additional evidence, in how many fields this tendency has become apparent. It can be recognized in genetics (...) with the molecular analysis of chromosomes and the enzymatic or metabolic interpretation of hereditary properties like the eyecolor of Drosophila. In a purely morphological branch like histology we do not ask merely for a differentiation of stained cell structure but we ask for the nature of the staining reaction; in nerve physiology we try to interpret conduction as alterations of protein lipoid layers; or in pathology where the age old syndrome of inflammation is explored with biochemical methods. I should mention molecular models of membranes and cell surfaces, the molecular interpretation of secretion and of the macroscopic phenomena of metabolism. Yet insofar as this yield of data could be designated as a trend, it would rather seem to be the natural outcome to be expected from the application of the analytic method of science. In one instance, however, this approach has been carried farther than in all the other fields, and it would seem to be worthwhile to pause for one moment to ask whether this case is important merely because of its technical implications or whether it is meaningful in a wider sense. (shrink)