Auditory hallucinations, network connectivity, and schizophrenia

Behavioral and Brain Sciences 27 (6):860-861 (2004)
Multidisciplinary studies indicate that auditory hallucinations may arise from speech perception neurocircuitry without disrupted theory of mind capacities. Computer simulations of excessive pruning in speech perception neural networks provide a model for these hallucinations and demonstrate that connectivity reductions just below a “psychotogenic threshold” enhance information processing. These data suggest a process whereby vulnerability to schizophrenia is maintained in the human population despite reproductive disadvantages of this illness.
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DOI 10.1017/S0140525X04280190
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