Earthquakes are among the world’s deadliest natural phenomena. On an increasingly crowded Earth, earthquake risk management therefore should be taken seriously as a global policy problem. Thus, this chapter discusses some of the ethical dimensions of earthquakes as a phenomenon of planetary significance in the Anthropocene. I do not attempt an exhaustive survey, but consider one background ethical issue: the kinds of harms that occur when an earthquake impacts human habitation. We may distinguish three categories of human-related harms: personal harms, which accrue to individual humans; social harms, which impact on social relationships between humans; and institutional harms, which compromise the ability of institutions to respond to the quake. This analysis will help us better appreciate the moral salience of earthquakes as a global policy imperative in the Anthropocene.