The maternal deprivation hypothesis was arguably the most discussed debate in midcentury psychiatry. Combined with the gender ideology prevalent in America and Britain, it solidified the idea that the mother-child relationship had formative influence on personality development. This essay explores the formation of this hypothesis by situating its knowledge claims against an institutional innovation set to prevent juvenile delinquency and promote mental hygiene, the establishment of child guidance clinics on both sides of the Atlantic in the late 1920s. It then (...) tracks the development of investigative agendas by child guidance practitioners, examining the practices they adopted to construct psychological knowledge claims in conformity with preventive objectives and positivist standards. Shifting the historiographical focus toward the clinical scenes in which psychological assertions were made, the essay examines how investigators sought to determine the “pathogenic” influence of early parental environment by way of estimating its emotional qualities. It argues that it was this positivist-determinist effort to achieve preventive goals that foregrounded the role of the mother in the etiology of personality disturbance and marked the knowledge field that came to be called the maternal deprivation debate. (shrink)

This article explores the development of a rat model of mother-infant relationships from its origins in the psychosomatic investigations of the mid-1960s to its elaboration into a theoretical system in neurobiology. I reconstruct the research trajectory of a group of neurobiologists in the United States, with a focus on the experimental practices they adopted while building this animal model. Providing a microhistory of this decade-long undertaking, I show that what drove the development of the model in practice was a serendipitous (...) finding about infants’ response to maternal separation. Detected inadvertently, the pup’s separation response acquired an epistemic significance of its own and reoriented the experimental system towards unanticipated paths. To explain this intriguing phenomenon, the neurobiologists kept on refining their material manipulations and stabilizing their experimental outcomes. They thus established a series of causal relationships that connected dysregulations of the infant’s physiological systems to disruptions in maternal care. As important as this interactive stabilization of technique and objects in the laboratory was how the researchers theorized the network of relationships derived from this technically constituted objectivity. Highlighting the practice-driven aspects of model-building, I demonstrate that what facilitated this theoretical process was an integrated design of complementary experiments. The outcome of each separate experiment of the research program came to bear upon the outcomes of other experiments, informing the development of future manipulations. It was this strategically driven integration process that allowed the experimenters to build expanding networks of causal relationships and consolidate them into a neurobiological theory. (shrink)