It is often said that clinical research and the practice of medicine are fraught with uncertainties. But what do we mean by uncertainty? Where does uncertainty come from? How do we measure uncertainty? Is there a single theory of uncertainty that applies across all scientific domains, including the science and practice of medicine? To answer these questions, we first review the existing theories of uncertainties. We then attempt to bring the enormous literature to bear from other disciplines to address the (...) issue of uncertainty in clinical research and medical practice. Our main and overarching goal is to review and classify uncertainties in clinical medicine. (shrink)

In this methods-building article, I show how attention to long-term continuities in female enslavement patterns helps us understand the emergence of the Black Atlantic. Slavery, I argue, is one form of human parasitism. I extend Orlando Patterson’s theory of human parasitism to examine the phenomenon of parasitic intertwining, wherein the forced labor of women became integral to broader social projects including household functioning, elite status maintenance, and population expansion. The thousand-year period between the fall of Rome and the rise of (...) the transatlantic slave trade was once described as a rupture in European slavery, with serfdom gradually supplanting slavery. The mass capture, transport, and enslavement of women, however, continued even as male slaves and ex-slaves gained significant status changes. The entrenchment of women in zonal slave trades generated both a potent cultural logic and a structural blueprint for the transatlantic trade. (shrink)

The reissue of Orlando Patterson’s Slavery and Social Death provides an opportunity to reflect on developments in studies of slavery, postcolonial sociology, and comparative-historical sociology since the book’s initial release in 1982. In this special issue of Theory and Society, contributors from ancient history, anthropology, and sociology examine the book’s broader intellectual significance by situating it in Patterson’s corpus, covering a range of works including his fiction and scholarly publications, early work on Jamaican slave revolts, and private correspondence with key (...) thinkers. The volume’s ambit, then, is not a single book but rather a broader field of social thought. As the articles in this issue demonstrate, the concepts and theories introduced by Patterson are still vital. In some ways, we argue, a Pattersonian sociology has only recently come to its full fruition, thanks to ongoing developments in postcolonial studies, critical race studies, anthropological and historical study of slavery, globalization studies, and feminist theory. (shrink)