The fetal human possesses an active central nervous system from at least the eighth week of development. Until mid-gestation the most significant center of activity is the brainstem. By the end of the first trimester, it appears that the brainstem could be acting as a rudimentary modulator of sensory information and motor activity. What importance ought to be attached to such regulatory activity is uncertain. Some argue that it represents a level of integrated activity sufficient to bolster an argument for (...) conferring some measure of standing at this point. Our thinking about sentience is not advanced a great deal, as we as yet have no good way of talking about it at the brainstem level. As for the neocortex, available evidence indicates that it does not become a functional part of the neuraxis until at least mid-gestation. It is not until then that the thalamus – the major gateway for sensory input to the cerebrum – makes its first afferent contacts with the neocortex. Keywords: neuromaturation, fetal behavior, fetal brainstem CiteULike Connotea Del.icio.us What's this? (shrink)

The public debate on recombinant DNA research has ended even though significant issues of public interest remain undecided or untouched. The reason for the termination of other than muted public discussion is not simply the removal of an initial fear of catastrophic biohazards. With the cessation of public debate over such hazards came also the dissolution of most public forums. The ends to which recombinant DNA research and development ought to be directed are not matters of public debate. With the (...) transfer of basic research knowledge to the private sector, that sector's proprietary interests and ownership prerogatives effectively deny any continued public participation in charting the future of genesplicing technology and its application. (shrink)