Whipple disease is a rare, infectious, disease first described from a single case by Whipple in 1907. As well as characterising the clinical and pathological features of the condition, Whipple made two suggestions regarding its aetiology. These were either than the disease was caused by an infectious agent, or that it was of metabolic origin. As the disease is now thought to be caused by infection with the bacterium Tropheryma whipplei, historical reviews of the history of the disease typically mention (...) only the first of these suggestions. In this paper, we therefore revisit Whipple’s other theory. We argue that a diverse and often successful research programme was developed around this mechanism of disease causation which gave rise to many useful findings on the condition. In the later parts of this article, we then turn to discuss the surprising neglect of this period of Whipple disease research in the current literature, and conclude by offering a brief reconstruction of this early history suitable for use in a technical context. (shrink)

Rousseau avait tout lieu, dans la controverse qui oppose au xviii e siècle partisans et pourfendeurs des voyages d’éducation, de prendre position contre ces voyages, suivant en cela les déclarations de Béat de Muralt, qu’il approuvait dans une large mesure. Nous constatons pourtant qu’en abordant « la question des voyages », l’auteur de l’Émile se voit obligé, tout en condamnant cette « mode », à la manière de Muralt, d’opérer un glissement théorique et de conférer à l’expérience du voyage, comme (...) expérience critique de la pluralité et de la liberté, une place essentielle dans son système, place rendue nécessaire par sa théorie des affects politiques. (shrink)

The basis for ‘sound’ medical opinion has moved from clinical opinion to evidence based research. This article will comment on the basis on which evidence in clinical medicine is collected and, indeed, what actually constitutes evidence. It is suggested that the definition of guidelines arising from evidence-based medicine may lead to false conclusion and, as noted by Sir Douglas Black, whilst ‘guidelines can of course be helpful in clear-cut situations; [but] these are the minority in actual practice’.

Placing the question -- Patristic Precedents -- Moltmann's perichoretic spaces for God and creation -- No place for the spirit? Jean-Luc Marion's placial refusal -- Notes toward a Trinitarian theology of Place.

This volume of Eurasian Studies in Business and Economics includes selected papers from the 24th Eurasia Business and Economics Society (EBES) Conference, held in Bangkok. The theoretical and empirical papers gathered here cover diverse areas of business and management from different geographic regions; yet the main focus is on the latest findings on evolving marketing methods, analytics, communication standards, and their effects on customer value and engagement. The volume also includes related studies that analyze sustainable consumer behavior, and business strategy-related (...) topics such as cross-border restructuring, quality management standards, and the internationalization of SMEs. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:86. THE HUME LITERATURE FOR 1977 In my recently-published book, Fifty Years of Hume Scholarship: A Bibliographical Guide (Edinburgh University Press, 1978; ^ 5.50), the reader will find a thorough coverage of the Hume literature from 1925 to 1976, with lists of the main earlier writings on Hume, all indexed by author, language, and subject. What follows here will bring the record up to the end of 1977.· Readers (...) are invited to inform me of any omissions. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography covering the previous year, with addenda consisting of items omitted through ignorance in previous years. The following abbreviations of journal titles are used here: APQ American Philosophical Quarterly JHI Journal of the History of Ideas JHP Journal of the History of Philosophy JP Journal of Philosophy PAS Proceedings of the Aristotelian Society PB Philosophical Books PBA Proceedings of the British Academy PQ Philosophical Quarterly PR Philosophical Review RIP Revue Internationale de Philosophie RM Review of Metaphysics TLS Times Literary Supplement Other abbreviations should be obvious enough, and mainly follow the British Standard. ÄRDAL, P. S. 'Convention and Value',in G. P. Morice, David Hume, Bicentenary Papers,51-68. Edinburgh. ÁRDAL, P. S. 'Another Look at Hume'sAccount of Moral Evaluation', JHP 15, 405-21. 87. BERK, E.? Note on Hume's Treatise I. iv. 1', Mind 86, 118-19. BERLIN, I. 'Hume and the Sources of German Anti-Rationalism', in Morice, op. cit., 95-116. BERRY, C. J. 'From Hume to Hegel: The Case of the Social Contract', JHI 38, 691-703. BOTWINICK, A.? Case for Hume's Nonutilitarianism', JHP 15, 423-35. BRADLEY, M. C. 'Stove on Hume', Australas. J. Phil. 55, 69-73. BRANDT, R. 'The Beginnings of Hume's Philosophy', in Morice, op. cit., 117-27. BRICKE, J. 'Hume on Self-Identity, Memory and Causality', in Morice, op. cit., 167-74. BRITTON, K. 'Hume on some Non-Natural Distinctions', in Morice, op. cit., 205-9. BURKS, A. W. Chance, Cause, Reason, esp. 128-42 ('Hume's thesis on the justification of induction'). Chicago. CASSIDY, J. 'The Nature of Hume's Inductive Scepticism: A Critical Notice', Ratio 19, 47-54. (on Stove 1973) COHEN, E. D. 'Hume's Fork', Sth. J. Phil. 15, 443-55. CONNON, R. W. 'The Textual and Philosophical Significance of Hume's MS Alterations to Treatise III ', in Morice, op. cit., 186-204. [PQ 28 (1978), 265-8] CONNON, R. W. & POLLARD, M. On the Authorship of "Hume's" Abstract', PQ 27, 60-6. CORSANO, A. 'Vico et Hume face au problème religieux', Archives de Phil. 40, 241-50. DAVIE, G. E. 'Edmund Husserl and "the as yet, in its most important respect, unrecognised greatness of Hume",' in Morice, op. cit., 69-76. DAVIS, J. W. 'Hume on Qualitative Content', in Morice, op. cit., 175-80. DELEULE, D. Hume, Lettre d'un Gentilhomme à son ami d'Edimbourg, présentation, traduction et notes. Paris. (French translation, with facing original, of A Letter from a Gentleman, Edinburgh, 1745) 88. DÉME", N. 'La Méthode Newtonienne et les Lois Empiriques de l'Anthropologie dans Traité II', in Morice, op. cit., 139-45. FORBES, D. 'Hume's Science of Polities', in Morice, op. cit., 39-50. FORCE, J. E. 'Hume in the Dialogues, the Dictates of Convention, and the Millennial Future State of Biblical Prophecy', S. -west. J. Phil. 8, 131-41. GAWLICK, G. 'Hume and the Deists: a Reconsideration', in Morice, op. cit., 128-38. GLOSSOP, R. J. 'In defence of David Hume', Australas. J. Phil. 55, 59-63. GLOUEERMAN, M. 'Hume on Modes', Hume Studies 3, 32-50. GUPTA, B. 'Buddha and Hume: A Popular Comparison Revisited ', Int. Phil. Q. 17 (1977), 135-46. HALL, R. 'The Hume Literature for 1976', Hume Studies 3, 94-102. HEALY,. M. 'Substance and Spiritual Substance - A criticism of David Hume', Alethe ia (Irving, Texas) 1 (1977), 159-83. HEDENIUS, I. Filosofien i ett föränderligt samhälle, 37-59 ( ' Värdeteorierna hos Hume': the value-theories in Hume). Stockholm. HINCKFUSS, I. 'Stove, Induction and the Irish', Australas. J. Phil. 55, 64-8. HISKES... (shrink)