Formaldehyde is one of the potent toxic industrial chemicals that are very commonly used in various industries, labs, and biological museums, etc. The toxicity of formaldehyde is well-known. It causes respiratory distress if inhaled in higher concentration thus, causing lung damage. It is also found to be mutagenic due to its rapid reactivity being a small molecule having electrophilic carbon. The current review focuses on the characteristic properties of formaldehyde, Sources, and uses of formaldehyde. This review further brings about the (...) toxicity of formaldehyde on different organs and organ systems of the body. Its genotoxicity and carcinogenicity are described. And later the various ways of decontaminating the formaldehyde are discussed to neutralize its harmful impacts. From this review, we have concluded that formaldehyde is a highly toxic chemical that needs proper protective measures while handling and should not be directly exposed. There should be proper decontaminating agents for emergencies, where there is the mass production of formaldehyde. (shrink)

Nanoparticles have been used in numerous fields, various branches of science and engineering. These were used as a modification and to enhance the activity such as dentistry and oral investigation. The current survey uncovers that graphene oxide has been used to set up a variety of functionalized nanoparticles and progressed nanocomposites carriers. Graphene oxide shows potential in a variety of research examinations, for instance, tooth bleaching, antimicrobial activity, tooth erosion, teeth implants, toothaches, drug delivery at a specific site. All these (...) usages of graphene oxide to biomedicine are excellent, and consoling Graphene oxide use in dental science has given amazing outcomes in antimicrobial activity, bone tissue building, regenerative dental, advancing dentistry biological materials, and in the treatment of oral cancer. The biocompatibilities of graphene oxide and its nanomaterial make them approaching units in bone regeneration, osseointegration, and cell multiplication. Furthermore, its antibiofilm and antiadhesion action encouraged researchers to formulate graphene oxide for biofilm. Nanostructures are utilized advancements or exploration of dentistry, and nanocomposite is employed for oral ailment preventive drugs, prostheses, and teeth implantation. Nanomaterials are further utilized as an oral liquid, mouth wash, or medication, forestalling and facilitating some oral malady and keep up oral wellbeing. (shrink)

Influenza virus (H1N1) caused seasonal influenza, is an acute respiratory infection that spreads to whole worldwide. The first case of influenza A virus pandemics in India came to light in May 2009 in Hyderabad city of Telangana. Human-to-human transmission led to considerable morbidity and mortality within the country until December.The total number of seasonal influenza cases in India from the year 2010 to 31st July 2020 is 1,73,488. Decreasing ambient temperature is often associated with influenza weather. The viral particle's ability (...) to survive long term in cold temperatures also plays an important role. Besides, coagulation during winter serves as a co-contributing factor in facilitating the spread of the influenza virus. The environmental temperature leads to physical stress and energy loss due to thermal regulation, which weakens the immune system and thereby increases the host's likelihood of infection. The prevention of epidemics in India was possible only by quick and efficient measures taken by the Government.Soon after cases were registered at Pune, Maharashtra, and other places across the country, steps were taken to revise the guidelines for the control of the disease in India.Classification of cases in health facilities and home environments, classification of cases, providing treatment to appropriate persons, public education, and other appropriate measures proved to be very effective in due course of time. In this paper, we discussed the total cases and mortality due to seasonal influenza virus in the states and union territories in India from the year 2010 to the year 2020. (shrink)

Purpose of Review Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is identified from Wuhan, China, and has spread almost worldwide. Recently, the newly identified SARS-CoV-2 has been confirmed to kill millions of people worldwide and is dangerous to society health, survival, and livelihood. The people with cardiovascular problems are noticed as most common patients of coronavirus disease 2019 (COVID-19). There is a greater risk of mortality and morbidity in these patients than other patients of COVID-19. In the heart, expressed angiotensin-converting enzyme (...) 2 (ACE2) and response effect of hyperactivity with angiotensin II associated to the renin-angiotensin mechanism are key factors of hypertension, atherosclerosis, and congestive heart failure. -/- Recent Findings Mortality rates have been observed about 10.5% cases in patients with cardiovascular disease; however, a mortality rate of 52% was recorded in patients with heart failure, while 12% recovered ultimately. The occupancy of intense injury controlled by troponin elevation was a noteworthy factor in relation to mortality. Among 187 patients infected with SARS-CoV-2, about 35% were diagnosed with cardiovascular disease (CVD) history and 28% with raised troponin. Troponin elevation was identified more frequently (55%) in patients with cardiovascular diseases. Mortality rate in patients without cardiovascular diseases and normal troponin was 7.6%, normal troponin and cardiovascular disease with 13.3%, augmented troponin and without cardiovascular disease 37.5%, however 69.4% among cardiovascular disease and advanced troponin. -/- Summary The study reflected a significant association of case fatality rate (CFR) to COVID-19 patients with cardiovascular diseases which supposed to be the most common dangerous risk factor and health challenge during the current pandemic situation. (shrink)

Proceedings of International Virtual Seminar on Recent Trends in Life Sciences and Biotechnology: Strategies to Combat COVID-19, Zoonoses and Other Communicable Diseases. Rakesh Book Service, New Delhi. 460p (ISBN: 978-93-84998-83-7).

India is the leading producer of fruits worldwide. The major problem after citrus fruits consumption is their peel that are hazardous to our environment and mainly regarded as a solid waste however, they are rich sources of fibres, large amount of Vitamin C, phenolics and flavonoids which are best agents of antioxidant. In this paper, we have discussed about the orange peel waste which has many beneficial roles in our daily life. Citrus peel has the highest number of Phytochemicals such (...) as flavonoids, terpenoids, quinolines and having highest antioxidant activity as compared to the pulp and seed as well as identified from the extraction. The different Phytochemicals test analysis have been discussed in this paper (steroids testing, saponins testing) and different antioxidant test used to check the antioxidant activity of the citrus fruit peel extract are Hydrogen peroxide scavenging test, Nitric oxide scavenging test, DPPH test etc. The main objective of this paper is that the higher antioxidant activity of different mixture of Citrus fruit peel can help to reduce the generation of free radicals and can act as an anti-proliferative agent. The search for novel drugs and alternative medicine especially against cancer has led to increased research in medicinal plants. This review also indicated that Citrus peels contains antioxidant compounds which could be exploited as value added products in the food and cosmetic industry. (shrink)

Résumé: L’image du “Dragon baignant le prince” est un thème important dans l’art bouddhique. L’image est née en Inde, et pendant le processus de propagation du bouddhisme vers l’est, elle est apparue dans le Xinjiang, le Gansu, le Qinghai, le Shanxi, le Shaanxi, le Henan, le Shandong, le Jiangsu, le Sichuan, le Tibet et d’autres endroits en Chine. Cependant, la forme et le contenu de ces images sont différents selon les régions et les périodes. L’étude de cette différence est non (...) seulement propice à la compréhension du processus de sinisation de l’art bouddhiste indien, mais approfondit également la compréhension du contenu spécifique de l’échange de l’art bouddhiste l’art entre la Chine et l’Inde. (shrink)

Whereas classical Critical Theory has tended to view phenomenology as inherently uncritical, the recent upsurge of what has become known as critical phenomenology has attempted to show that phenomenological concepts and methods can be used in critical analyses of social and political issues. A recent landmark publication, 50 Concepts for Critical Phenomenology, contains no reference to psychiatry and psychopathology, however. This is an unfortunate omission, since the tradition of phenomenological psychiatry—as we will demonstrate in the present article by surveying and (...) discussing the contribution of Jaspers, Minkowski, Laing, Basaglia, and Fanon—from the outset has practiced critical thinking, be it at the theoretical, interpersonal, institutional, or political level. Fanon is today a recognized figure in critical phenomenology, even if his role in psychiatry might not yet have been appreciated as thoroughly as his anticolonial and antiracist contributions. But as we show, he is part of a long history of critical approaches in psychopathology and psychiatry, which has firm roots in the phenomenological tradition, and which keeps up its critical work today. (shrink)

Some medical services have long generated deep moral controversy within the medical profession as well as in broader society and have led to conscientious refusals by some physicians to provide those services to their patients. More recently, pharmacists in a number of states have refused on grounds of conscience to fill legal prescriptions for their customers. This paper assesses these controversies. First, I offer a brief account of the basis and limits of the claim to be free to act on (...) one’s conscience. Second, I sketch an account of the basis of the medical and pharmacy professions’ responsibilities and the process by which they are specified and change over time. Third, I then set out and defend what I call the “conventional compromise” as a reasonable accommodation to conflicts between these professions’ responsibilities and the moral integrity of their individual members. Finally, I take up and reject the complicity objection to the conventional compromise. Put together, this provides my answer to the question posed in the title of my paper: “Conscientious refusal by physicians and pharmacists: who is obligated to do what, and why?”. (shrink)

Many philosophers believe that when a theory is committed to an apparently unexplainable massive correlation, that fact counts significantly against the theory. Philosophical theories that imply that we have knowledge of non-causal mind-independent facts are especially prone to this objection. Prominent examples of such theories are mathematical Platonism, robust normative realism and modal realism. It is sometimes thought that theists can easily respond to this sort of challenge and that theism therefore has an epistemic advantage over atheism. In this paper, (...) I will argue that, contrary to widespread thought, some versions of theism only push the challenge one step further and thus are in no better position than atheism. (shrink)

How should modern medicine's dramatic new powers to sustain life be employed? How should limited resources be used to extend and improve the quality of life? In this collection, Dan Brock, a distinguished philosopher and bioethicist and co-author of Deciding for Others (Cambridge, 1989), explores the moral issues raised by new ideals of shared decision making between physicians and patients. The book develops an ethical framework for decisions about life-sustaining treatment and euthanasia, and examines how these life and death decisions (...) are transformed in health policy when the focus shifts from what is best for a patient to what is just for all patients. Professor Brock combines acute philosophical analysis with a deep understanding of the realities of clinical health policy. This is a volume for philosophers concerned with medical ethics, health policy professionals, physicians interested in bioethics, and undergraduate courses in biomedical ethics. (shrink)

Several authors believe that there are certain facts that are striking and cry out for explanation—for instance, a coin that is tossed many times and lands in the alternating sequence HTHTHTHTHTHT…. According to this view, we have prima facie reason to believe that such facts are not the result of chance. I call this view the striking principle. Based on this principle, some have argued for far-reaching conclusions, such as that our universe was created by intelligent design, that there are (...) many universes other than the one we inhabit, and that there are no mathematical or normative facts. Appealing as the view may initially seem, I argue that we lack sufficient reason to accept it. (shrink)

Motivated by examples, many philosophers believe that there is a significant distinction between states of affairs that are striking and therefore call for explanation and states of affairs that are not striking. This idea underlies several influential debates in metaphysics, philosophy of mathematics, normative theory, philosophy of modality, and philosophy of science but is not fully elaborated or explored. This paper aims to address this lack of clear explanation first by clarifying the epistemological issue at hand. Then it introduces an (...) initially attractive account for strikingness that is inspired by the work of Paul Horwich and adopted by a number of philosophers. The paper identifies two logically distinct accounts that have both been attributed to Horwich and then argues that, when properly interpreted, they can withstand former criticisms. The final two sections present a new set of considerations against both Horwichian accounts that avoid the shortcomings of former critiques. It remains to be seen whether an adequate account of strikingness exists. (shrink)

Reviews the history of teaching in the United States over three hundred years, and describes aspects of recruitment, organization, and logic particular to the profession.

This book argues that political libertarianism can be grounded in widely shared, everyday moral beliefs--particularly in strictures against shifting our burdens onto others. It also seeks to connect these philosophical arguments with related work in economics, history, and politics for a wide-ranging discussion of political economy.

Faced with the choice between supporting industrial plant agriculture and hunting, Tom Regan’s rights view can be plausibly developed in a way that permits a form of hunting we call “dignitarian.” To motivate this claim, we begin by showing how the empirical literature on animal deaths in plant agriculture suggests that a non-trivial amount of hunting would not add to animal harm. We discuss how Tom Regan’s miniride principle appears to morally permit hunting in that case, and we address recent (...) objections by Jason Hanna to environmentally-based culling that may be seen to speak against this conclusion. We then turn to dignity, which is especially salient in scenarios where harm is necessary or justifiable. We situate “dignitarian” hunting within a larger framework of adversarial ethics, and argue that dignitarian hunting gives animals a more dignified death than the alternatives endemic to large-scale plant agriculture, and so is permissible based on the kinds of principles that Regan endorses. Indeed, dignitarian hunting may actually fit better with Regan’s widely endorsed animal rights framework than the practice of many vegans, and should only be rejected if we’re just as willing to condemn supporting conventional plant agriculture. (shrink)

[Updated 2/23/21: complete chapter scan] In this chapter I sketch a rightist approach to monumentary policy in a diverse polity beleaguered by old ethnic grievances. I begin by noting the importance of tribalism, memorialization, and social trust. I then suggest a policy which 1) gradually narrows the gap between peoples in the heritage landscape, 2) conserves all but the most offensive of the least beloved racist monuments, 3) avoids recrimination (i.e., “keeps it positive”) and eschews ideological commentary in new monuments (...) or revisions to old ones, 4) as much as politically feasible, recognizes only the offense of willing tribemates, and 5) responds to aesthetic and other “irrational” offenses more than to “objective” historical or philosophical critiques. (shrink)

It is widely recognized that prioritizing health care resources by their relative cost-effectiveness can result in lower priority for the treatment of disabled persons than otherwise similar non-disabled persons. I distinguish six different ways in which this discrimination against the disabled can occur. I then spell out and evaluate the following moral objections to this discrimination, most of which capture an aspect of its unethical character: it implies that disabled persons' lives are of lesser value than those of non-disabled persons; (...) it constitutes “double jeopardy” or violates Frances Kamm's non-linkage principle; it conflicts with equality of opportunity; it conflicts with fairness, which requires ignoring (some/most) differential impacts of treatment; it wrongly gives lower priority to disabled persons for equally effective treatment; it conflicts with giving all persons an equal chance to reach their full potential; and, it is in conflict with giving priority to the worse off. (shrink)

This study focuses on the effects of socially responsible human resource management practices on female employees’ turnover intentions and the moderating effect of supervisor gender on this relationship. With a sample of 212 female employees from eight different industries in Finland, the results indicate that SR-HRM practices promoting equal career opportunities and work–family integration play a significant role in reducing women's turnover intentions. The study adds to the academic discourse of corporate social responsibility by highlighting the impact of the organizational-level (...) HRM determinants on the individual-level outcome. In addition, supervisor gender makes a difference in the studied relationship: female supervisors have a stronger and more significant impact on the relationship than male supervisors. Our findings suggest that organizational measures which support work–family integration should be taken seriously to decrease female employees’ turnover intentions. Male supervisors could adopt some gender-incongruent leadership behaviors, such as individualized emotional concern and caring when dealing with female employees. In the future, other gender combinations in the supervisor–employee relationship would merit research. (shrink)

Analytic Philosophy, Volume 62, Issue 1, Page 97-105, March 2021.

A number of philosophers have recently claimed that intrinsicality can be analysed in terms of the metaphysical notion of grounding. Since grounding is a hyperintensional notion, accounts of intrinsicality in terms of grounding, unlike most other accounts, promise to be able to discriminate between necessarily coextensive properties that differ in whether they are intrinsic. They therefore promise to be compatible with popular metaphysical theories that posit necessary entities and necessary connections between wholly distinct entities, on which it is plausible that (...) there are such properties. This paper argues that this promise is illusory. It is not possible to give an analysis of intrinsicality in terms of grounding that is consistent with these theories. Given an adequate analysis should be compatible with these theories, it follows that it is not possible to analyse intrinsicality in terms of grounding. (shrink)

This paper presents a novel approach to the unsupervised learning of syntactic analyses of natural language text. Most previous work has focused on maximizing likelihood according to generative PCFG models. In contrast, we employ a simpler probabilistic model over trees based directly on constituent identity and linear context, and use an EM-like iterative procedure to induce structure. This method produces much higher quality analyses, giving the best published results on the ATIS dataset.

We present a generative distributional model for the unsupervised induction of natural language syntax which explicitly models constituent yields and contexts. Parameter search with EM produces higher quality analyses than previously exhibited by unsupervised systems, giving the best published unsupervised parsing results on the ATIS corpus. Experiments on Penn treebank sentences of comparable length show an even higher F1 of 71% on nontrivial brackets. We compare distributionally induced and actual part-of-speech tags as input data, and examine extensions to the basic (...) model. We discuss errors made by the system, compare the system to previous models, and discuss upper bounds, lower bounds, and stability for this task. (shrink)

I argue for the merits of studying historical moral revolutions to inform moral and political philosophy. Such a research program is not merely of empirical, historical interest but has normative implications. To explain why, I situate the proposal in the tradition of naturalized epistemology. As Alison M. Jaggar and other scholars have argued, a naturalistic approach is characteristic of much feminist philosophy. Accordingly, I argue that the study of moral revolutions would be especially fruitful for feminist moral and political philosophers.

The intense and extensive debate over human embryonic stem cell research has focused primarily on the moral status of the human embryo. Some commentators assign full moral status of normal adult human beings to the embryo from the moment of its conception. At the other extreme are those who believe that a human embryo has no significant moral status at the time it is used and destroyed in stem cell research. And in between are many intermediate positions that assign an (...) embryo some degree of moral status between none and full. This controversy and the respective positions, like the abortion controversy, is by now well understood, despite the lack of progress in resolving it. I have argued briefly elsewhere that early embryos do not have significant moral status, but I do not want to reenter that debate here. Instead, I want to focus on an issue that has had relatively little explicit and separate attention, but is likely to loom larger in light of the Obama administration’s partial lifting of the Bush administration’s restriction on the embryos that can be used in stem cell research that receives federal funding. (shrink)

Several theorists have been attracted to the idea that in order to account for counterpossibles, i.e. counterfactuals with impossible antecedents, we must appeal to impossible worlds. However, few have attempted to provide a detailed impossible worlds account of counterpossibles. Berit Brogaard and Joe Salerno’s ‘Remarks on Counterpossibles’ is one of the few attempts to fill in this theoretical gap. In this article, I critically examine their account. I prove a number of unanticipated implications of their account that end up implying (...) a counterintuitive result. I then examine a suggested revision and point out a surprising implication of the revision. (shrink)

Combining careful historical and textual analysis with comparisons across past and present political theory, this book re-establishes Spinoza as a collectivist philosopher.

It is sometimes said that a society should be judged ethically by how it treats its least-fortunate or worst-off members. In one interpretation this is not a point about justice, but instead about moral virtues such as compassion and charity. In our response to the least fortunate among us, we display, or show that we lack, fundamental moral virtues of fellow feeling and concern for others in need. In a different interpretation, however, this point is about justice and a just (...) society—the justice of a society is shown especially in how it treats its least-fortunate members. (shrink)

This paper presents empirical studies and closely corresponding theoretical models of the performance of a chart parser exhaustively parsing the Penn Treebank with the Treebank’s own CFG grammar. We show how performance is dramatically affected by rule representation and tree transformations, but little by top-down vs. bottom-up strategies. We discuss grammatical saturation, including analysis of the strongly connected components of the phrasal nonterminals in the Treebank, and model how, as sentence length increases, the effective grammar rule size increases as regions (...) of the grammar are unlocked, yielding super-cubic observed time behavior in some configurations. (shrink)

In this article I shall analyse and evaluate analytic theists’ views of what it takes to be a person of faith. I suggest that the subject can be approached by posing requirements a person must allegedly fulfil in order to count as a person of faith. These requirements can be referred to as aspects of faith. According to my analysis, four different aspects of faith can be distinguished: the cognitive, the evaluative-affective, the practical, and the interpersonal. There have been divergent (...) assessments about which aspects are indispensable for faith and how they should be understood. (shrink)

According to the orthodox interpretation of bounce cosmologies, the universe was born from an entropy-reducing phase in a previous universe. To defend the thesis that the whole of physical reality was caused to exist a finite time ago, Craig and Sinclair have argued the low-entropy interface between universes should instead be understood as the beginning of two universes. Here, I present Craig and Sinclair with a dilemma. On the one hand, if the direction of time is reducible, as friends of (...) the Mentaculus—for example, Albert, Loewer, and Papineau—maintain, then there is reason to think that the direction of time and the entropic arrow of time align. But on that account, efficient causation is likely reducible to non-causal phenomena. In consequence, contrary to Craig and Sinclair’s theological aims, things can begin to exist without causes. On the other hand, if the direction of time is not reducible, Craig and Sinclair’s interpretation of bounce cosmologies is unjustified. Lastly, a reply to a potential objection motivates a discussion of how to interpret bounce cosmologies on the tensed theory of absolute time favoured by Craig and Sinclair. I offer two interpretations of bounce cosmologies that, given a tensed theory of absolute time, are preferable to those Craig and Sinclair offer, yet inconsistent with their project in natural theology; on one interpretation, the universe does not require a supernatural cause and, on the other, bounce cosmologies represent the universe as never having begun to exist. (shrink)

Rationing is the allocation of a good under conditions of scarcity, which necessarily implies that some who want and could be benefitted by that good will not receive it. One reflection of our ambivalence towards health care rationing is reflected in our resistance to having it distributed in a market like most other goods—most Americans reject ability to pay as the basis for distributing health care. They do not view health care as just another commodity to be distributed by markets. (...) Despite this widespread view, we are the only developed country without some form of universal health insurance, and so for the 46 million Americans without health insurance their access to health care often does depend on their ability to pay for it. Rationing largely remains a topic that the public, their elected leaders, and many health care professionals prefer to avoid. Ever-growing costs of health care will increasingly force the practice and issue of health care resource prioritization and rationing into the open for public, professional, and political attention. This paper explores some of the features of those practices and issues that make them especially ethically and politically difficult. Those issues will not be easily resolved, but avoiding them will not avoid the need or reality of rationing, it will only mean that it will go on covertly and unexamined. That will lead neither to better or more legitimate prioritization and rationing decisions. (shrink)

In their reviews, Chater and Oaksford, Dutilh Novaes, and Sterelny are critical of our modularist approach to reason. In this response, we clarify our claim that reason is one of many cognitive modules that produce intuitive inferences each in its domain; the reason module producing intuitions about reasons. We argue that in‐principle objections to the idea of massive modularity based on Fodor's peculiar approach are not effective against other interpretations that have led to insightful uses of the notion in psychology (...) and biology. We explain how the reason module evaluates reasons on the basis of their metacognitive properties. We show how the module fulfils a social function, that of producing reasons to justify oneself and convince others and of evaluating the reasons others produce to convince us. (shrink)

Despite the effort on DSM-5 and ICD-11, few appear satisfied with these classification systems. We suggest that the core reason for dissatisfaction is expecting too much from them; they do not provide discrete categories that map to specific causes of disease, they describe clinical syndromes intended to guide treatment choices. Here we review work on anxiety and anxiety disorders to argue that while clinicians draw a pragmatic distinction between normal and abnormal emotions based on considerations such as severity and duration, (...) understanding the evolutionary origins and utility of the emotions, including the adaptive value of adverse emotions, is key for formulating comprehensive assessments of an individual patient’s symptoms and for providing a conceptual foundation for pharmacotherapy, psychotherapy, and public health. (shrink)

In this paper I address the relation between just claims to health care and severe cognitive impairment from dementia. Two general approaches to justice in allocation of health care are distinguished – prudential allocation and interpersonal distribution. First, I analyze why a patient who has died has no further claims to health care. Second, I show why prudential allocators would not provide for health care treatment should they be in a persistent vegetative state. Third, I argue that the destruction of (...) personal identity from severe dementia implies that only claims to palliative, but not life-sustaining, health care remain. Finally, I argue that the prudential allocator approach is indeterminate regarding life-sustaining care for the moderately demented and that social policy should not deny that care to patients. Keywords: elderly, health care, the severely-demented, justice CiteULike Connotea Del.icio.us What's this? (shrink)

This paper separates conditional parameter estima- tion, which consistently raises test set accuracy on statistical NLP tasks, from conditional model struc- tures, such as the conditional Markov model used for maximum-entropy tagging, which tend to lower accuracy. Error analysis on part-of-speech tagging shows that the actual tagging errors made by the conditionally structured model derive not only from label bias, but also from other ways in which the independence assumptions of the conditional model structure are unsuited to linguistic sequences. The (...) paper presents new word-sense disambiguation and POS tagging experiments, and integrates apparently conflicting reports from other recent work. (shrink)