Background Inadequate knowledge among health care providers (HCPs) and parents of affected children limits the understanding and utility of secondary genetic findings (SFs) in under-represented populations in genomics research. SFs arise from deep DNA sequencing done for research or diagnostic purposes and may burden patients and their families despite their potential health importance. This study aims to evaluate the perspective of both groups regarding SFs and their choices in the return of results from genetic testing in the context of orofacial (...) clefts.Methods Using an online survey, we evaluated the experiences of 252 HCPs and 197 parents across participating cleft clinics in Ghana and Nigeria toward the return of SFs across several domains.Results Only 1.6% of the HCPs felt they had an expert understanding of when and how to incorporate genomic medicine into practice, while 50.0% agreed that all SFs should be returned to patients. About 95.4% of parents were willing to receive all the information from genetic testing (including SFs), while the majority cited physicians as their primary information source (64%).Conclusions Overall, parents and providers were aware that genetic testing could help in the clinical management of diseases. However, they cited a lack of knowledge about genomic medicine, uncertain clinical utility, and lack of available learning resources as barriers. The knowledge gained from this study will assist with developing guidelines and policies to guide providers on the return of SFs in sub-Saharan Africa and across the continent. (shrink)

At the forefront of critically examining the effects of colonization on the Middle East is Edward Said’s magnum opus, Orientalism. In the broadest theoretical sense, Said’s work through deconstructing colonial discourses of power-knowledge, presented an epistemologico-methodological equation expressed most lucidly by Aimé Césaire, colonization=thingification. Said, arguing against that archaic historicized discourse, Orientalism, was simply postulating that colonialism and its systems of knowledges signified the colonized, in Anouar Abdel-Malek’s words, as customary, passive, non-participating and non-autonomous. Nearly four decades later, Said’s contribution (...) has become tamed and domesticated to an extent that most heterodoxic critical endeavours in the field have become clichéd premeditated anti-Orientalist tirades. At best, these critiques are stuck at analysing the impact of power at the macro-level, polemically regurgitating jargons like “hegemony”, “misrepresentation” and “Otherness”. At worst... (shrink)

The idea of afro-existentialism connotes how Africans make sense of living and the meaning and meaninglessness attached to human existence. Different phenomena inform the way humans interpret existence, and one of such in the contemporary period, with great influence on Africans, is human involvement with non-human intelligence, in its different eruptions. This paper focuses on the second-wave AI, which is a period of improved simulation of natural intelligence, whose singularity principle hypothesizes individualist motives. The paper asks, to what extent do (...) Afroexistential norms accommodate second-wave AI? Partly in disagreement with the claim that AI is for everyone, we argue that second-wave artificial intelligence weakly adapts to Afro-existential practices, which is largely communal, emphasizing shared experience. We justify this claim by arguing that Western ethical patterns, which inform the features of the second-wave AI such as statistical patterns, smart algorithm, specialized hardware, and big data sets, emerge from individualist notions. This paper argues that second-wave AI trends do not reflect African norms of existence being factored into ordering algorithmic patterns that set up AI systems and programs. We infer that Afro-existential practices unsettles with the individualist principle which underlines second-wave AI and therefore, a conversation around the development and application of communal interpretation of AI is important. (shrink)

Using the matched wife fertility intention. The analysis used logistic regression models for predicting the effects of selected socioeconomic background characteristics on a couples fertility intention was associated with age, education, place of residence, frequency of television-watching and number of living children. Therefore, programme interventions aimed at promoting fertility reduction in Nigeria should convey fertility regulation messages to both husbands and wives.