The aim of this paper is to emphasize the theoretical and aesthetical meanings of Plessner’s aesthesiology. His theory on the unity of the senses allows to legitimate the normative sense of sensibility and his pregnancy to understand the organization of experience. Such an aesthetical perspective has also relevant implications for Plessner’s philosophical anthropology and his theory of eccentric positionality of human being, which is mainly a theory on the body-mind philosophical conjunction.