Neuroethics 6 (3):473-481 (2013)

Frederic Gilbert
University of Tasmania
The goal of this article is to shed light on Deep Brain Stimulation (DBS) postoperative suicidality risk factors within Treatment Resistant Depression (TRD) patients, in particular by focusing on the ethical concern of enrolling patient with history of self-estrangement, suicide attempts and impulsive–aggressive inclinations. In order to illustrate these ethical issues we report and review a clinical case associated with postoperative feelings of self-estrangement, self-harm behaviours and suicide attempt leading to the removal of DBS devices. Could prospectively identifying and excluding patients with suicidality risk factors from DBS experimental trials—such as history of self-estrangement, suicide attempts and impulsive–aggressive inclinations—lead to minimizing the risk of suicidality harm?
Keywords Deep Brain Stimulation  Eligibility  Exclusion  Experimental trial  Feelings of self-estrangement  Impulsive–aggressive disorder  Suicide  Treatment Resistant Depression
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DOI 10.1007/s12152-013-9178-8
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A Threat to Autonomy? The Intrusion of Predictive Brain Implants.Frederic Gilbert - 2015 - American Journal of Bioethics Neuroscience 6 (4):4-11.

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