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  1.  7
    Review of the Ethical Issues of a Biomarker-Based Diagnoses in the Early Stage of Alzheimer’s Disease. [REVIEW]Gwendolien Vanderschaeghe, Kris Dierickx & Rik Vandenberghe - 2018 - Journal of Bioethical Inquiry 15 (2):219-230.
    Background: Today, many healthcare or dementia organizations, clinicians, and companies emphasize the importance of detection of Alzheimer’s disease in an early phase. This idea has gained considerable momentum due to the development of biomarkers, the recent FDA and EMA approval of three amyloid tracers, and the failure of a number of recent therapeutic trials conducted in the early dementia phase. On the one hand, an early etiological diagnosis can lead to early and more efficacious intervention. On the other hand, it (...)
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  2.  7
    Amnestic MCI Patients’ Perspectives on Volunteer Participation in a Research Context.Gwendolien Vanderschaeghe, Jolien Schaeverbeke, Rik Vandenberghe & Kris Dierickx - 2017 - Journal of Clinical Research and Bioethics 8 (3).
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    Amnestic MCI Patients’ Perspectives Toward Disclosure of Amyloid PET Results in a Research Context.Gwendolien Vanderschaeghe, Jolien Schaeverbeke, Rik Vandenberghe & Kris Dierickx - 2017 - Neuroethics 10 (2):281-297.
    BackgroundResearchers currently are not obligated to share individual research results with participants. This non-disclosure policy has been challenged on the basis of participants’ rights to be aware and in control of their personal medical information. Here, we determined how patients view disclosure of research PET results of brain amyloid and why they believe it is advantageous or disadvantageous to disclose.MethodAs a part of a larger diagnostic trial, we conducted semi-structured interviews with patients with amnestic Mild Cognitive Impairment. Participants had the (...)
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