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  1.  70
    Discovery by Serendipity: A New Context for an Old Riddle. [REVIEW]Pio García - 2009 - Foundations of Chemistry 11 (1):33-42.
    In the last years there has been a great improvement in the development of computational methods for combinatorial chemistry applied to drug discovery. This approach to drug discovery is sometimes called a “rational way” to manage a well known phenomenon in chemistry: serendipity discoveries. Traditionally, serendipity discoveries are understood as accidental findings made when the discoverer is in quest for something else. This ‘traditional’ pattern of serendipity appears to be a good characterization of discoveries where “luck” plays a key role. (...)
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  2. Experimentación, materialidad y simulaciones computacionales.Pío García, Juan M. Durán & José Ahumada - 2013 - In A. Torrano & A. Passos Videira (eds.), Representación en Ciencia y Arte. Editorial Brujas. pp. 73-82.
  3.  16
    Computer Simulations and Experiments: In Vivo–in Vitro Conditions in Biochemistry.Pio Garcia - 2015 - Foundations of Chemistry 17 (1):49-65.
    Scientific practices have been changed by the increasing use of computer simulations. A central question for philosophers is how to characterize computer simulations. In this paper, we address this question by analyzing simulations in biochemistry. We propose that simulations have been used in biochemistry long before computers arrived. Simulation can be described as a surrogate relationship between models. Moreover, a simulative aspect is implicit in the classical dichotomy between in vivo–in vitro conditions. Based on a discussion about how to characterize (...)
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  4. Programas de investigación y estrategias metodológicas: cuestiones conceptuales e históricas.Pío García - 2021 - Páginas de Filosofía 21 (24):9-37.
    En los años veinte del siglo pasado se constituye lo que luego se llamó la escuela de Cambridge en bioquímica. Bajo el liderazgo de Frederick Gowland Hopkins este grupo tenía como objetivo primario la consolidación de la naciente bioquímica. Una característica particular de este grupo fue el intento explícito de vincular el trabajo científico con la discusión filosófica. Sin embargo, algunos historiadores como Nils Roll-Hansen han cuestionado en duros términos la manera en la cual estos científicos apelaban a la filosofía. (...)
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