Metaphilosophy 38 (2-3):309–329 (2007)

David DeGrazia
George Washington University
The creation of chimeras by introducing human stem cells into nonhu- man animals has provoked intense concerns. Addressing objections that appeal to human dignity, I focus in this essay on stem cell research intended to generate human neurons in Great Apes and rodents. After considering samples of dignity- based objections from the literature, I examine the underlying assumption that nonhuman animals have lower moral status than personsFwith particular attention to what it means to speak of higher and lower moral statusFbefore evaluating the chimera research in question. I argue that (1) such experiments involving Great Apes should be prohibited out of respect for the research subjects and (2) such experiments involving rodents may or may not be permissible, depending on how we answer unresolved questions regarding rodents’ moral status. In the end, concerns about human dignity prove insignificant.
Keywords stem cells  Great Apes  moral status  human dignity  rodents  stem cell research  human‐animal chimeras  chimeras  embryonic stem cell research
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DOI 10.1111/j.1467-9973.2007.00476.x
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References found in this work BETA

Freedom of the Will and the Concept of a Person.Harry G. Frankfurt - 1971 - Journal of Philosophy 68 (1):5-20.
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Citations of this work BETA

The Road Not Mapped: The Neuroethics Roadmap on Research with Nonhuman Primates.L. Syd M. Johnson - 2020 - American Journal of Bioethics Neuroscience 11 (3):176-183.
Transferring Morality to Human–Nonhuman Chimeras.Monika Piotrowska - 2014 - American Journal of Bioethics 14 (2):4-12.
Can a Chimp Say "No"? Reenvisioning Chimpanzee Dissent in Harmful Research.Andrew Fenton - 2014 - Cambridge Quarterly of Healthcare Ethics 23 (2):130-139.

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