This article begins with some common or well-known sentiments about the present pandemic era and our experience of it, and moves by way of these toward discussion of the concepts of human existence and the “world” in the broadest sense of both terms. Departing from but also radicalizing the notion that “everything changed” in this pandemic time, I discuss certain logical difficulties that pertain to conceiving of or coherently talking about strict totalities which would include our own selves. This will (...) have significant consequences for our conception of the world (when taken in its absolute or broadest sense), and in what sense there are or could be multiple such immersive wholes of experience. Ultimately, I will suggest that in being able to name such pervasive or all encompassing phenomena, phenomena which are “always more” than what it is possible for us to indicate, that human existence is fundamentally liminal, or essentially between and borderline. Being essential or fundamental, this liminality or betweenness will form the basis which precedes and makes possible the apparently simple activities of, for instance, counting time or comparing and contrasting ordinary things, activities which would otherwise seem to require no outside support or conditions. (shrink)

Until 1923 most critics were content to interpret as ‘a reversal o fortune’. Then, in ‘The Reverse of Aristotle’ , Mr. F. L. Lucas argued persuasively for Vahlen's interpretation of the term as ‘a reversa of intention’, ‘any event where the agent's intention is over-ruled to produce an effect the exact opposite of his intention’. The result has been wide acceptanct for Vahlen's theory. This may be a case of truth prevailing after two thousanc years of error, but it looks (...) to me more like an instance of quid facundia posset I suggest that we simple-minded Ajaxes have fallen victims to the wit of Odysseus. (shrink)

It is a challenge in teaching early modern philosophy to balance historical faithfulness to the arguments and concerns of early modern philosophers and interpreting them as relevant to the kinds of thinking that contemporary undergraduate students find plausible. Early modern philosophy is unique, however, in applying modern scientific method directly to problems concerning nonphysical aspects of reality that our contemporary scientific thought, and with it mainstream contemporary culture, no longer find amenable in their own, independent right to reliable reasoned approaches. (...) At the same time, early modern philosophy often also takes seriously purely conceptual or logically consequential thought in the investigation of these topics, as our mainstream contemporary culture does not. This kind of thought, we argue, is distinctive of philosophy in general and appropriate to nonphysical aspects of reality. Early modern philosophy, then, offers a bridge between the kind of reasoned, objective thought our mainstream culture finds plausible and thought about nonphysical reality or, in general, the thought that characterizes philosophy. (shrink)

Successful therapies to combat microbial diseases and cancers require incorporating ecological and evolutionary principles. Drawing upon the fields of ecology and evolutionary biology, we present a systems‐based approach in which host and disease‐causing factors are considered as part of a complex network of interactions, analogous to studies of “classical” ecosystems. Centering this approach around empirical examples of disease treatment, we present evidence that successful therapies invariably engage multiple interactions with other components of the host ecosystem. Many of these factors interact (...) nonlinearly to yield synergistic benefits and curative outcomes. We argue that these synergies and nonlinear feedbacks must be leveraged to improve the study of pathogenesis in situ and to develop more effective therapies. An eco‐evolutionary systems perspective has surprising and important consequences, and we use it to articulate areas of high research priority for improving treatment strategies. (shrink)

Until 1923 most critics were content to interpretas ‘a reversal o fortune’. Then, in ‘The Reverse of Aristotle’ (C.R. 1923, pp. 98–104), Mr. F. L. Lucas argued persuasively for Vahlen's interpretation of the term as ‘a reversa of intention’, ‘any event where the agent's intention is over-ruled to produce an effect the exact opposite of his intention’. The result has been wide acceptanct for Vahlen's theory. This may be a case of truth prevailing after two thousanc years of error, but (...) it looks to me more like an instance ofquid facundia possetI suggest that we simple-minded Ajaxes have fallen victims to the wit of Odysseus. (shrink)