Two decades have passed since the first attempts were made to establish systematic ethical review of human research in the Baltic States. Legally and institutionally much has changed. In this paper we provide an historical and structural overview of ethical review of human research and identify some problems related to the role of ethical review in establishing quality research environment in these countries. Problems connected to (a) public availability of information, (b) management of conflicts of interest, (c) REC composition and (...) motivation of REC members, and (d) differing levels of stringency of ethical review for different types of studies, are identified. Recommendations are made to strengthen cooperation among the Baltic RECs. (shrink)

Two decades have passed since the first attempts were made to establish systematic ethical review of human research in the Baltic States. Legally and institutionally much has changed. In this paper we provide an historical and structural overview of ethical review of human research and identify some problems related to the role of ethical review in establishing quality research environment in these countries. Problems connected to (a) public availability of information, (b) management of conflicts of interest, (c) REC composition and (...) motivation of REC members, and (d) differing levels of stringency of ethical review for different types of studies, are identified. Recommendations are made to strengthen cooperation among the Baltic RECs. (shrink)

The paper attempts to provide an updated and holistic description of the research ethics system in Latvia and discuses the problems in its structure and functioning. It is based on the data gathered in an empirical study of RECs in Central and Eastern Europe in 2008 and it is structured according to the integrated framework proposed by Hyder et al. First a short outline of the historical development of the ethics review system in the 1990s is given, then the issues (...) of general social, political and economic background and the resultant enabling conditions, as well as the national and regional strategy of ethical review are reviewed. Next, the discussion turns to institutional commitment, the factors influencing the quality of review, and ethically relevant aspects of investigators’ behavior. The main conclusion is that current developmental conditions are not too favorable for research ethics review; despite the overall progress, several crucial enabling conditions are not in place yet. (shrink)