"The largest Ebola outbreak to date—first detected in December 2013 and still ongoing as of April 2015—has cast new light on the shortfalls of international public health systems.1 As in previous health crises, scrutiny has reemerged over the pharmaceutical industry’s ability and willingness to innovate new medicines for underserved disease areas. The public debate has intensified following revelations that promising drug candidates to treat Ebola had gone undeveloped despite compelling preclinical results.2 This lack of development is especially troubling because it (...) occurred after a recently implemented U.S. incentive scheme—the Food and Drug Administration’s (FDA) tropical disease priority review voucher program—designed to counteract exactly this problem. Taking Ebola as a case in point, it is useful to examine the short history and ongoing refinement of this voucher program, since it represents one of the most significant legislative efforts to systematically address the relative absence of com- mercial rewards for drugs targeting tropical diseases. This analysis evaluates the voucher program’s effectiveness for both stimulating private sector innovation and achieving positive health impacts among populations most severely burdened by tropical diseases. It then proposes specific recommendations for how law- makers can improve the program’s legislation to better achieve these objectives. ". (shrink)

Der Dialog ist als Mittel und direkter Ausdruck zwischenmenschlicher Kommunikation in unserer Gesellschaft wichtiger denn je. Zugleich ist er aber zunehmend von Gewalt, von medialen Auswüchsen und von der Schnelllebigkeit unserer Zeit bedroht. Angesichts dieser Entwicklung ist Martin Bubers „dialogisches Prinzip“ hochaktuell. Sein Verständnis des Dialogs unterscheidet sich fundamental vom heutigen medialen Diskurs. In seinem Hauptwerk Ich und Du beschreibt Buber die Grundbedingungen für einen guten Dialog. Ein solcher kann nur gelingen, wenn zwei Menschen bereit sind, sich voll und ganz (...) aufeinander einzulassen und dem anderen ohne Vorbehalte oder Vorurteile zu begegnen. Ausgehend von einer Werk- und einer Werkgeschichtsanalyse von Ich und Du reflektiert Gertud Arnold das Potenzial des Buberschen Dialogkonzepts und dessen praktischer Anwendung im Hier und Heute. (shrink)

Why do people buy particular products? Which are the antecedents that lead to the decision in favour of or against the purchase? Knowledge of the underlying semiotic and perceptual mechanisms is of key importance for understanding marketing processes. There are different psychological approaches that help to explain the effects of advertisements and product design. Analysing the sign processes of marketing clarifies the strategies applied. By identifying the manipulative functions of advertising, this book supports the consumers' critical discourse.

Le conseil d’administration du CNRS a adopté le 23 juin 2011 la charte interne de l’expertise, qui adapte aux spécificités de ses propres activités le texte de la Charte nationale de l’expertise. La charte interne du CNRS est guidée par la volonté de répondre efficacement à deux enjeux majeurs de l’expertise scientifique : la crédibilité des experts et la qualité du processus et du produit de l’expertise.The CNRS governing board adopted its internal Charter on Expert Studies on 23 June 2011, (...) which adapts the National Charter on Expert Studies to the specific features of CNRS activities. The internal CNRS Charter rests on the principle of efficient striving to address two major issues concerning scientific expert studies : the credibility of experts and the quality of expert study processes and output. (shrink)

Dans le domaine biomédical, qui est l’objet principal de cet article, la littérature montre une corrélation directe entre le financement d’une recherche par un industriel et la communication de résultats qui lui sont favorables. Cet effet, appelé « le biais de financement », persiste depuis les travaux des années 1990 jusqu’aux travaux récents. Il peut être élargi à d’autres domaines tels que l’agro-alimentaire, l’étude des risques environnementaux et sanitaires, etc. Les conflits d’intérêts peuvent influencer la recherche par des voies inconscientes (...) ou volontaires. Nous analysons les modes d’action possibles des conflits d’intérêts sur le déroulement de l’activité scientifique, ainsi que l’efficacité des diverses solutions qui ont été proposées pour gérer ces influences.In the field of biomedicine, which is the main object addressed in this article, the literature shows a direct correlation between industrial funding for research and the communication of results that are favourable to the industry. This effect, known as the “ funding effect”, has been persistenly found since the 1990s. It can also affect other fields such as agri-foods or environmental and health risk assessments. Conflicts of interest can influence research subconsciously or deliberately. In this article, we analyse the various ways in which conflicts of interest can influence the way scientific activities proceed, as well as the effectiveness of the different solutions put forward to manage the influence exerted. (shrink)