Functional diversity holds the promise of understanding ecosystems in ways unattainable by taxonomic diversity studies. Underlying this promise is the intuition that investigating the diversity of what organisms actually do—i.e. their functional traits—within ecosystems will generate more reliable insights into the ways these ecosystems behave, compared to considering only species diversity. But this promise also rests on several conceptual and methodological—i.e. epistemic—assumptions that cut across various theories and domains of ecology. These assumptions should be clearly addressed, notably for the sake (...) of an effective comparison and integration across domains, and for assessing whether or not to use functional diversity approaches for developing ecological management strategies. The objective of this contribution is to identify and critically analyze the most salient of these assumptions. To this aim, we provide an “epistemic roadmap” that pinpoints these assumptions along a set of historical, conceptual, empirical, theoretical, and normative dimensions. (shrink)

OBJECTIVE: To describe the issues faced, and how they were addressed, by the University of Toronto Critical Care Medicine Program/Joint Centre for Bioethics Task Force on Appropriate Use of Life-Sustaining Treatment. The clinical problem addressed by the Task Force was dealing with requests by patients or substitute decision makers for life-sustaining treatment that their healthcare providers believe is inappropriate. DESIGN: Case study. SETTING: The University of Toronto Joint Centre for Bioethics/Critical Care Medicine Program Task Force on Appropriate Use of Life-Sustaining (...) Treatment. PARTICIPANTS: The 24-member Task Force included physician and nursing leaders from five critical care units, bioethicists, a legal scholar, a health administration expert, a social worker, and a hospital public relations professional. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Our specific lessons learned include a) a policy focus on process; b) use of a negotiation and mediation model, rather than a hospital ethics committee model, for this process; and c) the policy development process is itself a negotiation, so we recommend equal involvement of interested groups including patients, families, and the public. CONCLUSIONS: This article describes the key issues faced by the Task Force while developing its policy. It will provide a useful starting point for other groups developing policy on appropriate use of life-sustaining treatment. (shrink)

Athenaeus records these lines from the dithyramb Hymenaios, along with a number of other snippets of poetry, in the course of an inconclusive discussion about the characteristics of the instrument called the magadis. Athenaeus had good reasons for being puzzled; the word first appeared in Greek, so far as we know, in the seventh century b.c., and its sense was already a matter of some doubt in the fourth. As to this particular fragment, even Telestes' original audience might be forgiven (...) some bafflement in the face of the third line, on which I shall initially focus here. What can be meant by ‘the five-rodded joining of the strings’? (shrink)

The social, educational and political writings of Jean-Jacques Rousseau have become enormously influential in the 200 years since his death. But the breadth as well as the depth of Rousseau's achievement - he was amongst other things a creative writer and musical composer as well as a philosopher - is not always appreciated. In around 100 articles, alphabetically arranged and fully cross-referenced, N. J. H. Dent explores all facets of Rousseau's work and thoughts, while his subject's remarkable life is summarized (...) in a biographical introduction. Details of works by and about Rousseau are listed in an extensive bibliography. For students or general readers seeking an introduction to Rousseau's work, and for those already familiar with the material who require a convenient reference source, this dictionary is essential reading. (shrink)

Bradford C Bemiss, Chad A WittDepartment of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, MO, USA: Chronic rejection is a major cause of death after the first year following lung transplantation. Bronchiolitis obliterans is the most common pathologic finding on biopsy, characterized by fibrous granulation tissue, which obliterates the lumen of the bronchiole. Clinically, in the absence of tissue for pathology, BO syndrome refers to a progressive irreversible drop in the forced (...) expiratory volume in 1 second. Recently, a broader definition of chronic rejection, termed "chronic lung allograft dysfunction", has been used to encompass a more inclusive definition of posttransplant dysfunction. Recently, the lung transplant community has come to realize that chronic rejection may be the final common result after repetitive epithelial insults. Acute rejection, infection, and alloreactivity to mismatched HLA antigens are a few of these insults that damage the surface of the bronchioles. Recent evidence of autoimmunity to the normally hidden structural proteins collagen V and K-α1 tubulin have been correlated with a BO phenotype as well, perhaps correlating the epithelial damage with a mechanism for developing BO lesions. Many immunomodulatory medications and treatments have been studied for effectiveness for the treatment of chronic lung allograft dysfunction. New drugs, which more precisely target the immune system, are being developed and tested. Further study is required, but recent advances have improved our understanding of the pathogenesis and potential intervention for this common and deadly complication of lung transplantation.Keywords: lung transplant, bronchiolitis obliterans syndrome, rejection. (shrink)

The United Nations Convention on the Rights of the Child risks harm to adolescents insofar as it encourages not only poor decision making by adolescents but also parenting styles that will have an adverse impact on the development of mature decision-making capacities in them. The empirical psychological and neurophysiological data weigh against augmenting and expression of the rights of children. Indeed, the data suggest grounds for expanding parental authority, not limiting its scope. At the very least, any adequate appreciation of (...) the moral claims regarding the authority of parents with respect to the decision-making capacity of adolescents needs to be set within an understanding of the psychological and neurophysiological facts regarding the development of adolescent decision-making capacity. (shrink)

Physics has been thought to truly represent reality since at least Galileo, and the foundations of physics are always established using philosophical ideas. In particular, the elegant naming of physical entities is usually very influential in the acceptance of physical theories. We here demonstrate (using current developments in thermodynamics as an example) that both the epistemology and the ontology of physics ultimately rest on poetic language. What we understand depends essentially on the language we use. We wish to establish our (...) knowledge securely, but strictly speaking this is impossible using only analytic language. Knowledge of the meanings of things must use a natural language designed to express meaning, that is, poetic language. Although the world is really there, and although we can indeed know it truly, this knowledge is never either complete or certain but ultimately must rest on intuition. Reading a recently discovered artefact with a palaeo-Hebrew inscription as from the first century, we demonstrate from it that this ontological understanding long predates the Hellenic period. Poetic language is primary, both logically and temporally. (shrink)

Contributed articles, with reference to India.

Aristotle, great Greek philosopher, researcher, reasoner, and writer, born at Stagirus in 384 BCE, was the son of Nicomachus, a physician, and Phaestis. He studied under Plato at Athens and taught there ; subsequently he spent three years at the court of a former pupil, Hermeias, in Asia Minor and at this time married Pythias, one of Hermeias's relations. After some time at Mitylene, in 343?2 he was appointed by King Philip of Macedon to be tutor of his teen-aged son (...) Alexander. After Philip's death in 336, Aristotle became head of his own school, the Lyceum at Athens. Because of anti-Macedonian feeling there after Alexander's death in 323, he withdrew to Chalcis in Euboea, where he died in 322. Nearly all the works Aristotle prepared for publication are lost; the priceless ones extant are lecture-materials, notes, and memoranda. They can be categorized as follows: I Practical: Nicomachean Ethics; Great Ethics ; Eudemian Ethics; Politics; Economics ; On Virtues and Vices. II Logical: Categories; Analytics ; Interpretation; Refutations used by Sophists; Topica. III Physical: Twenty-six works including astronomy, generation and destruction, the senses, memory, sleep, dreams, life, facts about animals, etc. IV Metaphysics: on being as being. V Art: Rhetoric and Poetics. VI Other works including the Constitution of Athens; more works also of doubtful authorship. VII Fragments of various works such as dialogues on philosophy and literature; and of treatises on rhetoric, politics and metaphysics. The Loeb Classical Library edition of Aristotle is in twenty-three volumes. (shrink)

The systems approach to niche presented herein stands as an example of the unifying potential of mathematical system theory when applied to concepts and principles of ecology. Beginning with subjective concepts from the naturalistic tradition, the niche was framed in the formalism of general system theory. So modeled, it appeared as a restriction of a more general construct, the environ. Both niches and environs are implementable in the context of ecosystem models, and with the growing ability of ecologists to construct (...) such models, system theoretic niches and environs both should serve in the future to clarify old problems of ecology, and make it possible to raise new classes of problems. The nature of niches, always difficult conceptually for the ecologist, may now give way to further development, both theoretical and empirical. (shrink)

It is often taken for granted that there is a crucial dichotomy between positive science, with its interest in what is the case, and morality, with its supposed interest in what ought to be the case. This assumption takes its departure from a belief in the notion of unconditional or categorical obligation or ?the moral? as ?that whose nature it is to be required or demanded?. The notion of unconditional or categorical obligation, together with the assumption that there is a (...) dichotomy between considerations of what is the case and what ought to be the case, however widespread and entrenched this notion and assumption might be, are logically confused. But to demonstrate this logical confusion is not the only task confronting ethical theory. Another, and often neglected task, is to draw attention to the ethical origins of this confusion in a particular way of life. Hegel's distinction between Moralität (Moral Life) and Sittlichkeit (Ethical Life) is of critical importance here. The obstacle to the development of ethical theory, then, is not some abstract ?logical confusion?, but is, rather, the way of life (Moral Life) of which this confusion is a natural expression. (shrink)

The paper is an attempt to make sense of Hegel's notion of aufheben. The double meaning of aufheben and its alleged ?rise above the mere ?either?or?; of understanding? have been taken, by some, to constitute a criticism of the logic of either?or. It is argued, on the contrary, that Hegel's notion of aufheben, explicated in its primary and philosophical context, turns out to be a substantiation of that logic. The intelligibility of the formula of either?or depends, for example, on the (...) categories of Being and Not?Being. But if these categories are regarded as particular finite determinations themselves subject to the formula of either?or, then the formula, far from being intelligible, ?falls apart?. Hegel is arguing, in other words, that if we are to substantiate the logic of either?or, we must, at the same time, ?rise above? that logic. The role of aufheben is then considered in the special sciences. Here it is argued that we must distinguish between empirical transitions, governed by the finite determinations of things, and logical or dialectical transitions, governed by considerations of the intelligibility of the notions involved. Applying the notion of aufheben to the former transitions suggests wrongly that empirical transitions have an objective or philosophic necessity. Finally, the place of ?immanent transformation? in the context of aufheben is examined. It is concluded that if there is to be a transformation, then a distinction must be drawn between thought and its content, but then the transformation cannot be regarded as immanent. (shrink)