Results for 'Oncology'

354 found
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  1.  43
    Moral distress in paediatric oncology: Contributing factors and group differences.Pernilla Pergert, Cecilia Bartholdson, Klas Blomgren & Margareta af Sandeberg - 2019 - Nursing Ethics 26 (7-8):2351-2363.
    Background:Providing oncological care to children is demanding and ethical issues concerning what is best for the child can contribute to moral distress.Objectives:To explore healthcare professionals’ experiences of situations that generate moral distress in Swedish paediatric oncology.Research design:In this national study, data collection was conducted using the Swedish Moral Distress Scale-Revised. The data analysis included descriptive statistics and non-parametric analysis of differences between groups.Participants and research context:Healthcare professionals at all paediatric oncology centres in Sweden were invited to participate. A (...)
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  2.  32
    Oncology patients’ perceptions of “the good nurse”: a descriptive study in Flanders, Belgium.Elisa Van der Elst, Bernadette Dierckx de Casterlé, Robin Biets, Leila Rchaidia & Chris Gastmans - 2013 - Medicine, Health Care and Philosophy 16 (4):719-729.
    The image of “the good nurse” is mainly studied from the perspective of nurses, which often does not match the image held by patients. Therefore, a descriptive study was conducted to examine oncology patients’ perceptions of “the good nurse” and the influence of patient- and context-related variables. A cross-sectional, comparative, descriptive design was used. The sample comprised 557 oncology patients at one of six Flemish hospitals, where they were treated in an oncology day-care unit, oncology hospital (...)
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  3. Oncology ontology in the NCI Thesaurus.Anand Kumar & Barry Smith - 2005 - Artificial Intelligence in Medicine:213-220.
    The National Cancer Institute’s Thesaurus (NCIT) has been created with the goal of providing a controlled vocabulary which can be used by specialists in the various sub-domains of oncology. It is intended to be used for purposes of annotation in ways designed to ensure the integration of data and information deriving from these various sub-domains, and thus to support more powerful cross-domain inferences. In order to evaluate its suitability for this purpose, we examined the NCIT’s treatment of the kinds (...)
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  4.  23
    Experimental treatments in oncology. Where are the ethical problems?Klaus Peter Rippe - 1998 - Ethik in der Medizin 10 (2):91-105.
    Definition of the problem: A `experimental treatment' is defined as the use of a not yet approved medical treatment or product in a single patient outside the scope of regular clinical trials. Especially in oncology the patient is usually in a desperate situation and does not respond to other treatments. Even if he or she is fully informed about the risks he or she may occasionally make an irrational decision.Discussion of the problem: The moral problems in experimental treatments have (...)
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  5.  11
    Oncology consent forms: failure to disclose off-site treatment availability.David B. Resnik, Shyamal Peddada, Jason Altilio, Nancy Wang & Jerry Menikoff - 2008 - IRB: Ethics & Human Research 30 (6):7.
    The objective of this study was to determine whether consent forms in oncology clinical trials of commercially available treatments inform subjects that they may be able to obtain the treatments being investigated without participating in research. We acquired consent forms from a random sample of U.S. oncology clinical trials in the ClinicalTrials.gov database. We then examined a subgroup of the sample consisting of studies in which the treatments under investigations were commercially available. Less than 20% of the consent (...)
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  6. Isn't All of Oncology Hermeneutic?Nancy J. Moules, David W. Jardine, Graham P. McCaffrey & Christopher B. Brown - 2013 - Journal of Applied Hermeneutics 2013 (1).
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  7.  12
    Psycho-Oncological Intervention Through Counseling in Patients With Differentiated Thyroid Cancer in Treatment With Radioiodine (COUNTHY, NCT05054634): A Non-randomized Controlled Study.Nuria Javaloyes, Aurora Crespo, M. Carmen Redal, Antonio Brugarolas, Lara Botella, Vanesa Escudero-Ortiz & Manuel Sureda - 2022 - Frontiers in Psychology 13.
    BackgroundDiagnosis and treatment of differentiated thyroid carcinomas cause anxiety and depression. Additionally, these patients suffer hormonal alterations that are associated with psychological symptoms. This study aims to evaluate the effectiveness of a psycho-oncological intervention based on counseling to reduce anxiety and depression related to the treatment in patients with DTC.MethodsA non-randomized controlled study, with two groups [experimental group, n = 37, and control group, n = 38] and baseline and posttreatment measures, was designed. Patients in the EG received a psycho-oncological (...)
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  8.  12
    Improving oncology first-in-human and Window of opportunity informed consent forms through participant feedback.Rebecca D. Pentz, R. Donald Harvey, Margie Dixon, Shannon Blee, Tekiah McClary, John Bourgeois, Eli Abernethy, Gavin Campbell, Hannah Claire Sibold & Anna M. Avinger - 2023 - BMC Medical Ethics 24 (1):1-7.
    BackgroundAlthough patient advocates have developed templates for standard consent forms, evaluating patient preferences for first in human (FIH) and window of opportunity (Window) trial consent forms is critical due to their unique risks. FIH trials are the initial use of a novel compound in study participants. In contrast, Window trials give an investigational agent over a fixed duration to treatment naïve patients in the time between diagnosis and standard of care (SOC) surgery. Our goal was to determine the patient-preferred presentation (...)
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  9.  11
    Molecular biomarkers in cardio‐oncology: Where we stand and where we are heading.Panagiotis V. S. Vasileiou, Gerasimos Siasos & Vassilis G. Gorgoulis - 2022 - Bioessays 44 (6):2100234.
    Until recently, cardiotoxicity in the setting of a malignant disease was attributed solely to the detrimental effects of chemo‐ and/or radio‐therapy to the heart. On this account, the focus was on the evaluation of well‐established cardiac biomarkers for the early detection of myocardial damage. Currently, this view has been revised. Cardiotoxicity is not restricted to a single organ but instead affects the endothelium as a whole. Indeed, it has come into light that not only cancer therapy but also malignant cells (...)
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  10.  27
    Paediatric oncology patients’ definitions of a good physician and good nurse.Elif Aşikli & Rahime Aydin Er - forthcoming - Nursing Ethics:096973302096149.
    Background: It is stated that the communication and disease experiences of paediatric patients, especially paediatric oncology patients, with healthcare professionals are completely different from those of adults. Objective: The aim of this study was to determine the definitions of a good physician and good nurse provided by elementary school-age oncology patients. Research design: In this qualitative research, data were collected through semi-structured individual interviews. The data were evaluated thorough thematic analysis. Participants and research context: Eighteen children hospitalised due (...)
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  11.  27
    Phase I oncology trials: why the therapeutic misconception will not go away.W. Glannon - 2006 - Journal of Medical Ethics 32 (5):252-255.
    In many cases, the “therapeutic misconception” may be an unavoidable part of the imperfect process of recruitment and consent in medical researchPaul Appelbaum, Loren Roth, and Charles Lidz coined the term “therapeutic misconception” in 1982.1 They described it as the misconception that participating in research is the same as receiving individualised treatment from a physician. It referred to the research subject’s failure to appreciate that the aim of research is to obtain scientific knowledge, and that any benefit to the subject (...)
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  12.  22
    Oncology patients' perceptions of" the good nurse": a descriptive study in.Elisa Van der Elst, Bernadette Dierckx de Casterlé, R. Biets, Leila Rchaidia & Chris Gastmans - forthcoming - Medicine, Health Care and Philosophy.
  13.  25
    Advance directives and cancer: oncology practices in Brazil.Eni Devay de Freitas & Rui Nunes - 2023 - Revista Bioética 31.
    Data on advance directives in Brazil are lacking. This study aims to assess the understanding of oncologists regarding advance directives and the frequency with which they discuss advance directives and advance care planning with their patients in Brazil. This is an observational, descriptive and cross-sectional study, conducted with cclinical oncologists associated with the Brazilian Society of Clinical Oncology. Participants were invited to answer a questionnaire prepared by the authors. In total, 72 physicians answered the questionnaire, of which 73% were (...)
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  14.  10
    Ethical issues in oncology practice: a qualitative study of stakeholders’ experiences and expectations.Gabriella Pravettoni, Paolo G. Casali, Virginia Sanchini & Chiara Crico - 2022 - BMC Medical Ethics 23 (1):1-15.
    BackgroundClinical Ethics Support Services have been established to support healthcare professionals in addressing ethically sensitive issues in clinical practice and, in many countries, they are under development. In the context of growing CESS, exploring how healthcare professionals experience and address clinical ethics issues in their daily practice represents a fundamental step to understand their potential needs. This is even more relevant in the context of extremely sensitive diseases, such as cancer. On this basis, we carried out a qualitative study conducting (...)
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  15.  73
    Ethical issues at the interface of clinical care and research practice in pediatric oncology: a narrative review of parents' and physicians' experiences.Martine C. de Vries, Mirjam Houtlosser, Jan M. Wit, Dirk P. Engberts, Dorine Bresters, Gertjan Jl Kaspers & Evert van Leeuwen - 2011 - BMC Medical Ethics 12 (1):1-11.
    Pediatric oncology has a strong research culture. Most pediatric oncologists are investigators, involved in clinical care as well as research. As a result, a remarkable proportion of children with cancer enrolls in a trial during treatment. This paper discusses the ethical consequences of the unprecedented integration of research and care in pediatric oncology from the perspective of parents and physicians. An empirical ethical approach, combining (1) a narrative review of (primarily) qualitative studies on parents' and physicians' experiences of (...)
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  16.  19
    The Need for Specialized Oncology Training for Clinical Ethicists.Eric C. Blackstone & Barbara J. Daly - 2024 - HEC Forum 36 (1):45-59.
    Numerous ethical issues are raised in cancer treatment and research. Informed consent is challenging due to complex treatment modalities and prognostic uncertainty. Busy oncology clinics limit the ability of oncologists to spend time reinforcing patient understanding and facilitating end-of-life planning. Despite these issues and the ethics consultations they generate, clinical ethicists receive little if any focused education about cancer and its treatment. As the field of clinical ethics develops standards for training, we argue that a basic knowledge of cancer (...)
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  17.  59
    Phase 1 oncology trials and informed consent.Franklin G. Miller & Steven Joffe - 2013 - Journal of Medical Ethics 39 (12):761-764.
    Ethical concerns have been raised about the quality of informed consent by participants in phase 1 oncology trials. Interview surveys indicate that substantial proportions of trial participants do not understand the purpose of these trials—evaluating toxicity and dosing for subsequent efficacy studies—and overestimate the prospect of therapeutic benefit that they offer. In this article we argue that although these data suggest the desirability of enhancing the process of information disclosure and assessment of comprehension of the implications of study participation, (...)
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  18.  21
    Oncologic multidisciplinary team meetings: evaluation of quality criteria.Nelleke Ottevanger, Mirrian Hilbink, Mariska Weenk, Romy Janssen, Talitha Vrijmoeth, Antoinette Vries & Rosella Hermens - 2013 - Journal of Evaluation in Clinical Practice 19 (6):1035-1043.
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  19.  20
    Possible directions of meaning in oncological disease: an experience of liminality, meaning making and existential planning.Stefano Benini - 2021 - ENCYCLOPAIDEIA 25 (59):57-70.
    The oncological disease experience is counted as a wound in the body and mind attributable to a traumatic experience that fragments and disorients the person’s biography. The neoplasia leaves marks and scars in both somatic and existential level. The illness experience suggests to patient to look for meaning that cannot be unheard. The literature associating the concept of liminality in oncological disease to understand the process of meaning making. The definition of new horizons of meaning, generated by crossing the limen, (...)
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  20.  28
    Personalised medicine in oncology: physicians’ perspectives concerning current developments in patient care.Sebastian Wäscher, Jan Schildmann, Caroline Brall & Jochen Vollmann - 2013 - Ethik in der Medizin 25 (3):205-214.
    Die öffentliche Diskussion um die „personalisierte Medizin“ legt nahe, dass mit diesem medizinischen Ansatz hohe Erwartungen an einen Beitrag zur klinischen Versorgung verbunden werden. Über die Wahrnehmungen und Bewertungen klinisch tätiger Ärzte ist jedoch wenig bekannt. Die vorliegende qualitative Interviewstudie gibt einen Einblick bezüglich des Einflusses „personalisierter Medizin“ auf die klinische Praxis aus ärztlicher Perspektive. Die Ärzte im vorliegenden Sample nehmen „personalisierte Medizin“ zwar als einen medizinischen Fortschritt wahr, sehen allerdings keine grundsätzliche Veränderung der bisherigen medizinischen Praxis. Als zentrales Problem (...)
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  21.  36
    The Children's Oncology Group Routinely Applies “Lack of Efficacy” Interim Monitoring to Its Randomized Clinical Trials.James R. Anderson & Mark Krailo - 2011 - American Journal of Bioethics 11 (3):18-19.
    (2011). The Children's Oncology Group Routinely Applies “Lack of Efficacy” Interim Monitoring to Its Randomized Clinical Trials. The American Journal of Bioethics: Vol. 11, No. 3, pp. 18-19.
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  22.  3
    Ethics in oncology nursing.Jeanne M. Erickson & Kate Payne (eds.) - 2016 - Pittsburgh, Pennsylvania: Oncology Nursing Society.
    Principles of ethics -- Medical research and clinical trials -- Treatment decision making -- Palliative and end-of-life care -- Patient advocacy -- Communication and ethics -- Genetics and genomics -- The impact of ethical conflict and dilemmas on nurses -- Ethics consultation and education.
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  23.  31
    Voluntary Informed Consent in Paediatric Oncology Research.Sara A. S. Dekking, Rieke Van Der Graaf & Johannes J. M. Van Delden - 2016 - Bioethics 30 (5):440-450.
    In paediatric oncology, research and treatments are often closely combined, which may compromise voluntary informed consent of parents. We identified two key scenarios in which voluntary informed consent for paediatric oncology studies is potentially compromised due to the intertwinement of research and care. The first scenario is inclusion by the treating paediatric oncologist, the second scenario concerns treatments confined to the research context. In this article we examine whether voluntary informed consent of parents for research is compromised in (...)
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  24.  30
    Voluntary Informed Consent in Paediatric Oncology Research.Sara A. S. Dekking, Rieke Van Der Graaf & Johannes J. M. Van Delden - 2015 - Bioethics 30 (6):440-450.
    In paediatric oncology, research and treatments are often closely combined, which may compromise voluntary informed consent of parents. We identified two key scenarios in which voluntary informed consent for paediatric oncology studies is potentially compromised due to the intertwinement of research and care. The first scenario is inclusion by the treating paediatric oncologist, the second scenario concerns treatments confined to the research context. In this article we examine whether voluntary informed consent of parents for research is compromised in (...)
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  25.  84
    The Clinical Oncology Information Network (COIN) Project: background, purpose and products.Stephen J. Karp - 1999 - Journal of Evaluation in Clinical Practice 5 (2):179-187.
  26.  13
    Experience of oncology residents with death: a qualitative study in Mexico.Asunción Álvarez-del-Río, Edwin Ortega-García, Luis Oñate-Ocaña & Ingrid Vargas-Huicochea - 2019 - BMC Medical Ethics 20 (1):1-13.
    Background Physicians play a fundamental role in the care of patients at the end of life that includes knowing how to accompany patients, alleviate their suffering and inform them about their situation. However, in reality, doctors are part of this society that is reticent to face death and lack the proper education to manage it in their clinical practice. The objective of this study was to explore the residents’ concepts of death and related aspects, their reactions and actions in situations (...)
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  27.  9
    Organizing Psycho-Oncological Care for Cancer Patients: The Patient’s Perspective.Anouk S. Schuit, Karen Holtmaat, Valesca van Zwieten, Eline J. Aukema, Lotte Gransier, Pim Cuijpers & Irma M. Verdonck-de Leeuw - 2021 - Frontiers in Psychology 12.
    BackgroundCancer patients often suffer from psychological distress during or after cancer treatment, but the use of psycho-oncological care among cancer patients is limited. One of the reasons might be that the way psycho-oncological care is organized, does not fit patients’ preferences. This study aimed to obtain detailed insight into cancer patients’ preferences regarding the organization of psycho-oncological care.Methods18 semi-structured interviews were conducted among cancer patients. Patients completed psycho-oncological treatment between 2015 and 2020 at the psychology department in a general hospital (...)
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  28.  8
    Stress and burnout among oncology nurses: review study.Przemysław Mateusz Domagała & Aleksandra Gaworska-Krzemińska - forthcoming - Polish Psychological Bulletin:482-488.
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  29.  8
    Psychological Burden and Psycho-Oncological Interventions for Patients With Hepatobiliary Cancers–A Systematic Review.Johanna Graf & Andreas Stengel - 2021 - Frontiers in Psychology 12.
    BackgroundWorldwide, hepatobiliary cancers are frequent diseases and often accompanied by a poor prognosis. These cancers, with hepatocellular carcinoma and cholangiocarcinoma being the most frequent, are often associated with a considerable amount of psychological burden such as anxiety, depressiveness, and reduced health-related quality of life which may lead to psychiatric comorbidities. This systematic review gives an overview on psychological burden and on the effectiveness of psycho-oncological interventions for patients with HCC and CHC.MethodsThe databases PubMed, PubPsych, and PsycINFO were used and searched (...)
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  30.  9
    The cancer multiple: Producing and translating genomic big data into oncology care.Peter A. Chow-White & Tiên-Dung Hà - 2021 - Big Data and Society 8 (1).
    This article provides an ethnographic account of how Big Data biology is produced, interpreted, debated, and translated in a Big Data-driven cancer clinical trial, entitled “Personalized OncoGenomics,” in Vancouver, Canada. We delve into epistemological differences between clinical judgment, pathological assessment, and bioinformatic analysis of cancer. To unpack these epistemological differences, we analyze a set of gazes required to produce Big Data biology in cancer care: clinical gaze, molecular gaze, and informational gaze. We are concerned with the interactions of these bodily (...)
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  31.  16
    Ethical climate and moral distress in paediatric oncology nursing.Päivi Ventovaara, Margareta af Sandeberg, Janne Räsänen & Pernilla Pergert - forthcoming - Nursing Ethics:096973302199416.
    Background: Ethical climate and moral distress have been shown to affect nurses’ ethical behaviour. Despite the many ethical issues in paediatric oncology nursing, research is still lacking in the field. Research aim: To investigate paediatric oncology nurses’ perceptions of ethical climate and moral distress. Research design: In this cross-sectional study, data were collected using Finnish translations of the Swedish Hospital Ethical Climate Survey–Shortened and the Swedish Moral Distress Scale–Revised. Data analysis includes descriptive statistics and non-parametric analyses. Respondents and (...)
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  32.  16
    Alcohol abuse in cancer patients: a shadow side in the oncological field and research.Stinne Glasdam & Christine Øye - 2014 - Medicine, Health Care and Philosophy 17 (3):437-446.
    This article aims to foreground alcohol abuse by cancer patients and explore how alcohol abuse functions as a biographic master motive and at the same time is a shadow side in the oncological field and research. The research is based on a single case study which draws on empirical material from interviews, field notes and staff policy, with analysis using Bourdieu’s concepts of trajectory of life and habitus. The findings show that the cancer patient’s alcohol abuse is an important part (...)
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  33.  33
    Unrealistic optimism in early-phase oncology trials.Lynn A. Jansen, Paul S. Appelbaum, William Mp Klein, Neil D. Weinstein, William Cook, Jessica S. Fogel & Daniel P. Sulmasy - 2011 - IRB: Ethics & Human Research 33 (1):1.
    Unrealistic optimism is a bias that leads people to believe, with respect to a specific event or hazard, that they are more likely to experience positive outcomes and/or less likely to experience negative outcomes than similar others. The phenomenon has been seen in a range of health-related contexts—including when prospective participants are presented with the risks and benefits of participating in a clinical trial. In order to test for the prevalence of unrealistic optimism among participants of early-phase oncology trials, (...)
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  34.  31
    Moral distress in nurses in oncology and haematology units.M. Lazzarin, A. Biondi & S. Di Mauro - 2012 - Nursing Ethics 19 (2):183-195.
    One of the difficulties nurses experience in clinical practice in relation to ethical issues in connection with young oncology patients is moral distress. In this descriptive correlational study, the Moral Distress Scale-Paediatric Version (MDS-PV) was translated from the original language and tested on a conventional sample of nurses working in paediatric oncology and haematology wards, in six north paediatric hospitals of Italy. 13.7% of the total respondents claimed that they had changed unit or hospital due to moral distress. (...)
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  35.  30
    The ethics of DNR-decisions in oncology and hematology care: a qualitative study.Mona Pettersson, Mariann Hedström & Anna T. Höglund - 2020 - BMC Medical Ethics 21 (1):1-9.
    BackgroundIn cancer care, do not resuscitate orders are common in the terminal phase of the illness, which implies that the responsible physician in advance decides that in case of a cardiac arrest neither basic nor advanced Coronary Pulmonary Rescue should be performed. Swedish regulations prescribe that DNR decisions should be made by the responsible physician, preferably in co-operation with members of the team. If possible, the patient should consent, and significant others should be informed of the decision. Previous studies have (...)
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  36.  57
    Unproven treatment in childhood oncology--how far should paediatricians co-operate?J. Jackson - 1994 - Journal of Medical Ethics 20 (2):77-79.
    How should doctors respond to requests from parents of terminally ill children for unproven treatments to be tried? Here it is argued that doctors faced with difficult cases where (1) it is not obviously against a child's interests to undergo an unproven treatment and (2) provided the treatment does not draw extravagantly on NHS funds, it may be appropriate, though not necessarily obligatory, for doctors to comply. It is important to recognise that often there may not be 'the right response'--only (...)
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  37.  24
    Ontario doctors' attitudes toward and use of clinical practice guidelines in oncology.Ian D. Graham, Melissa Brouwers, Christine Davies & Jacqueline Tetroe - 2007 - Journal of Evaluation in Clinical Practice 13 (4):607-615.
  38.  11
    Fostering Relationships in Pediatric Oncology Research: A Relational Ethics Approach to Clinically Integrated Research.Stephanie A. Kraft & Brittany M. Lee - 2021 - American Journal of Bioethics 21 (4):85-88.
    Ethical issues in biomedical research are traditionally examined as distinct from those of clinical care. However, this traditional framing may obscure questions of equity and fairness in both rese...
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  39. Principles of Oncology Nursing.T. Ades & P. Greene - forthcoming - Holleb Ai, Fink Dj, Murphy Gp, Organizadores. American Cancer Society of Clinical Oncology. Atlanta (Geo): American Cancer Society.
     
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  40.  13
    A critical exploration of nurses' perceptions of access to oncology care among Indigenous peoples: Results of a national survey.Tara C. Horrill, Donna E. Martin, Josée G. Lavoie & Annette S. H. Schultz - 2022 - Nursing Inquiry 29 (1):e12446.
    Inequities in access to oncology care among Indigenous peoples in Canada are well documented. Access to oncology care is mediated by a range of factors; however, emerging evidence suggests that healthcare providers, including nurses, play a significant role in shaping healthcare access. The purpose of this study was to critically examine access to oncology care among Indigenous peoples in Canada from the perspective of oncology nurses. Guided by postcolonial theoretical perspectives, interpretive descriptive and critical discourse analysis (...)
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  41.  32
    Ethical competence in DNR decisions –a qualitative study of Swedish physicians and nurses working in hematology and oncology care.Mona Pettersson, Mariann Hedström & Anna T. Höglund - 2018 - BMC Medical Ethics 19 (1):63.
    DNR decisions are frequently made in oncology and hematology care and physicians and nurses may face related ethical dilemmas. Ethics is considered a basic competence in health care and can be understood as a capacity to handle a task that involves an ethical dilemma in an adequate, ethically responsible manner. One model of ethical competence for healthcare staff includes three main aspects: being, doing and knowing, suggesting that ethical competence requires abilities of character, action and knowledge. Ethical competence can (...)
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  42. Transoral laser surgery for laryngeal carcinoma: has Steiner achieved a genuine paradigm shift in oncological surgery?A. T. Harris, Attila Tanyi, R. D. Hart, J. Trites, M. H. Rigby, J. Lancaster, A. Nicolaides & S. M. Taylor - 2018 - Annals of the Royal College of Surgeons of England 100 (1):2-5.
    Transoral laser microsurgery applies to the piecemeal removal of malignant tumours of the upper aerodigestive tract using the CO2 laser under the operating microscope. This method of surgery is being increasingly popularised as a single modality treatment of choice in early laryngeal cancers (T1 and T2) and occasionally in the more advanced forms of the disease (T3 and T4), predomi- nantly within the supraglottis. Thomas Kuhn, the American physicist turned philosopher and historian of science, coined the phrase ‘paradigm shift’ in (...)
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  43.  44
    Decision making in pediatric oncology: Views of parents and physicians in two European countries.Domnita O. Badarau, Katharina Ruhe, Thomas Kühne, Eva De Clercq, Anca Colita, Bernice S. Elger & Tenzin Wangmo - 2017 - AJOB Empirical Bioethics 8 (1):21-31.
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  44. Hypnosis, Meditation, and Self-Induced Cognitive Trance to Improve Post-treatment Oncological Patients’ Quality of Life: Study Protocol.Charlotte Grégoire, Nolwenn Marie, Corine Sombrun, Marie-Elisabeth Faymonville, Ilios Kotsou, Valérie van Nitsen, Sybille de Ribaucourt, Guy Jerusalem, Steven Laureys, Audrey Vanhaudenhuyse & Olivia Gosseries - 2022 - Frontiers in Psychology 13.
    IntroductionA symptom cluster is very common among oncological patients: cancer-related fatigue, emotional distress, sleep difficulties, pain, and cognitive difficulties. Clinical applications of interventions based on non-ordinary states of consciousness, mostly hypnosis and meditation, are starting to be investigated in oncology settings. They revealed encouraging results in terms of improvements of these symptoms. However, these studies often focused on breast cancer patients, with methodological limitations. Another non-ordinary state of consciousness may also have therapeutic applications in oncology: self-induced cognitive trance. (...)
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  45. Phase I Oncology Research.Manish Agrawal - 2008 - In Ezekiel J. Emanuel (ed.), The Oxford textbook of clinical research ethics. New York: Oxford University Press. pp. 356.
     
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  46.  19
    Mouse avatars of human cancers: the temporality of translation in precision oncology.Sara Green, Mie S. Dam & Mette N. Svendsen - 2021 - History and Philosophy of the Life Sciences 43 (1):1-22.
    Patient-derived xenografts are currently promoted as new translational models in precision oncology. PDXs are immunodeficient mice with human tumors that are used as surrogate models to represent specific types of cancer. By accounting for the genetic heterogeneity of cancer tumors, PDXs are hoped to provide more clinically relevant results in preclinical research. Further, in the function of so-called “mouse avatars”, PDXs are hoped to allow for patient-specific drug testing in real-time. This paper examines the circulation of knowledge and bodily (...)
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  47.  40
    Parents’ and Physicians’ Perceptions of Children’s Participation in Decision-making in Paediatric Oncology: A Quantitative Study.Michael Rost, Tenzin Wangmo, Felix Niggli, Karin Hartmann, Heinz Hengartner, Marc Ansari, Pierluigi Brazzola, Johannes Rischewski, Maja Beck-Popovic, Thomas Kühne & Bernice S. Elger - 2017 - Journal of Bioethical Inquiry 14 (4):555-565.
    The goal is to present how shared decision-making in paediatric oncology occurs from the viewpoints of parents and physicians. Eight Swiss Pediatric Oncology Group centres participated in this prospective study. The sample comprised a parent and physician of the minor patient. Surveys were statistically analysed by comparing physicians’ and parents’ perspectives and by evaluating factors associated with children’s actual involvement. Perspectives of ninety-one parents and twenty physicians were obtained for 151 children. Results indicate that for six aspects of (...)
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  48.  14
    The family meetings in oncology: some practical guidelines.Paolo Gritti - 2014 - Frontiers in Psychology 5.
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  49.  40
    Umbrella and basket trials in oncology: ethical challenges.Karolina Strzebonska & Marcin Waligora - 2019 - BMC Medical Ethics 20 (1):1-10.
    Novel precision oncology trial designs, such as basket and umbrella trials, are designed to test new anticancer agents in more effective and affordable ways. However, they present some ethical concerns referred to scientific validity, risk-benefit balance and informed consent. Our aim is to discuss these issues in basket and umbrella trials, giving examples of two ongoing cancer trials: NCI-MATCH (National Cancer Institute – Molecular Analysis for Therapy Choice) and Lung-MAP (Lung Cancer Master Protocol) study. We discuss three ethical requirements (...)
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  50.  29
    The Poster Child for the Need for Central Review of Research Protocols: The Children's Oncology Group.Rebecca D. Pentz & Anita F. Khayat - 2004 - Cambridge Quarterly of Healthcare Ethics 13 (4):359-365.
    Multiple groups, including the National Bioethics Advisory Commission, the American Society of Clinical Oncology, the National Coalition of Comprehensive Cancer Centers, Workgroup 6 of the Summit Series on Cancer, PRIM&R, the Bell Report, and prominent ethicists have called for replacing the current system of local institutional review with central review for multisite national trials. We argue that this need is particularly acute in pediatric oncology, as shown by the experience of the Children's Oncology Group.
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