Aggressive behavior is instinctively driven behavior that helps animals to survive and reproduce and is closely related to multiple behavioral and physiological processes. The dorsal raphe nucleus (DRN) is an evolutionarily conserved midbrain structure that regulates aggressive behavior by integrating diverse brain inputs. The DRN consists predominantly of serotonergic (5‐HT:5‐hydroxytryptamine) neurons and decreased 5‐HT activity was classically thought to increase aggression. However, recent studies challenge this 5‐HT deficiency model, revealing a more complex role for the DRN 5‐HT system in aggression. (...) Furthermore, emerging evidence has shown that non‐5‐HT populations in the DRN and specific neural circuits contribute to the escalation of aggressive behavior. This review argues that the DRN serves as a multifaceted modulator of aggression, acting not only via 5‐HT but also via other neurotransmitters and neural pathways, as well as different subsets of 5‐HT neurons. In addition, we discuss the contribution of DRN neurons in the behavioral and physiological aspects implicated in aggressive behavior, such as arousal, reward, and impulsivity, to further our understanding of DRN‐mediated aggression modulation. (shrink)

Diese Arbeit ist eine Interpretation zum Kapitel Das Gewissen der Phänomenologie des Geistes. Dabei bemüht die Autorin weder philologische noch sozialwissenschaftliche Methoden, sondern wendet sich direkt an das Denken Hegels. Nach Hegel wird in diesem Kapitel der Unterschied zwischen dem allgemeinen Ich und dem eigenen Ich unter Beweis gestellt.

近世を代表する思想家・伊藤仁斎。諸稿本に残る書き入れや訂正を基に、「庶民の道徳」を追究した仁斎の思想構造を浮き彫りにする。.

Every Christian who carefully reads the message of St. Apostle Paul, can not do it pay attention to the number of times he uses, so to speak, military terminology. Suffice it to read the sixth chapter of the epistle to the Ephesians - the words, which is also St. Mr. Patriarch Joseph finished his Testament: "Fix in the Lord and in the power of his power. Put on a full armor of God so that you can resist the tricks devilish (...) For we have to fight not against the body and blood, but against the beginning, against the authorities, against the rulers of this world of darkness, against the spirits of malice Therefore, take a full weapon God so that you can resist and... stand firmly. Stand, then, girth Your hips are right, putting on the armor of justice, and putting your legs ready preaching the gospel of peace. (shrink)

Intelligent neurotechnology is an emerging field that combines neurotechnologies like brain-computer interface (BCI) with artificial intelligence. This paper introduces a capability framework to assess the responsible use of intelligent BCI systems and provide practical ethical guidance. It proposes two tests, the threshold and flourishing tests, that BCI applications must meet, and illustrates them in a series of cases. After a brief introduction (Section 1), Section 2 sets forth the capability view and the two tests. It illustrates the threshold test using (...) examples from clinical medicine of BCI applications that enable patients with profound disabilities to function at a threshold level through computer mediation. Section 3 illustrates the flourishing test by exploring possible future applications of BCI involving neuroenhancements for healthy people, using examples adapted from research currently underway in the US military. Section 3 applies a capability lens to a complex case involving dual effects, both therapeutic and non-therapeutic, showing how the threshold and flourishing tests resolve the case. Section 4 replies to three objections: neurorights are the best tool for assessing BCI; the two tests are moving targets; and the analysis utilizes a capability view to do work it is not designed for. The paper concludes that a capability view offers unique advantages and gives practical guidance for evaluating the responsible use of present and future BCI applications. Extrapolating from our analysis may help guide other emerging technologies, such as germline gene editing, expected to impact central human capabilities. (shrink)

Defining value as the requiredness of an activity or object, the author describes value experiences and the nature, meaning, development, and function of value on the physical, psychological, and philosophical levels. Bibliogs.

The aim of this paper is to motivate and defend a conventional approach to assertion and other illocutionary acts. Such an approach takes assertions, questions and orders to be moves within an essentially rule-governed activity similar to a game. The most controversial aspect of a conventional account of assertion is that according to it, for classifying an utterance as an assertion, question or command, “it is irrelevant what intentions the person speaking may have had” (Dummett 1973, p. 302). I understand (...) this to mean that it is irrelevant for the issue of whether an utterance is an assertion whether the utterer has certain communicative intentions, such as the intention to utter something true, the intention to get one’s audience to believe (that one believes) what one has asserted etc. Just as one can commit a foul in football without meaning to do so, one can make an assertion, issue a command or ask a question without meaning to do so. The rules of football specify that a certain form of conduct (tackling an opponent in a certain way), carried out under certain general conditions (being a member of a team engaged in a game of football) counts as committing a foul. Similarly, I claim, the rules of language specify that a certain form of conduct (uttering an assertoric sentence), carried out under certain general conditions (being a member of a speech community engaged in a conversation) counts as making an assertion. (shrink)

Digital piracy as a continuing problem significantly impacts various stakeholders, including consumers, enterprises, and countries. This study develops a three-level mechanism of determinants of consumer digital piracy behavior, with personal risk as an individual factor, susceptibility to interpersonal influence as an inter-personal factor, and moral intensity as a broad societal factor. Further, it explores the role of rationalization and future piracy intent as outcomes of past piracy behaviors. The authors use survey data from four countries in the European Union to (...) test the system of structural relationships. With an exception of the effect of consumers’ susceptibility to interpersonal influence on piracy behavior, the conceptual model receives remarkably consistent support across the four countries. Specifically, perception of personal risk and moral intensity negatively affected the reported piracy behavior in all four countries. The results further support the negative influence of moral intensity and the positive influence of past digital piracy behavior on consumers’ use of rationalization. Lastly, personal risk, rationalization, and past digital piracy behavior directly influenced consumers’ intention to engage in digital piracy in the future. The study also discusses implications of the findings and identifies areas of future research. (shrink)