Resumo Este artigo apresenta um referencial pragmatista para compreender o estatuto epistêmico da valoração que é produzida na reflexão acerca das consequências sociais de propostas científicas e tecnológicas. O problema é posto, seguindo-se as considerações de Bertrand Russell sobre o impacto da ciência na sociedade. Russell argumenta que a valoração de arranjos sociais fica fora dos limites do conhecimento, porque valorações não podem ser verdadeiras ou falsas, em sentido correspondencial. Isso leva o pensamento social a um impasse, pois não se (...) pode saber que dado arranjo social seria indesejável ou inadequado. Este texto esboça uma alternativa, a partir dos trabalhos sobre valoração de Clarence Irving Lewis, tomados em continuidade com a teoria da investigação de John Dewey. Esse referencial alternativo assume noções epistêmicas de verdade e justificação, o que permite que valorações possam ser concebidas em contextos de investigação e, assim, como objetos de conhecimento.This article presents a pragmatist framework to understand the epistemic status of valuations produced upon reflection on social consequences of scientific and technological proposals. The problem is set following Bertrand Russell’s considerations on the impact of science on society. Russell argues that valuating social arrangements falls beyond the limits of knowledge, because valuations cannot be true or false in the sense of correspondence. This leads social thought to a deadlock, since one cannot know that a given social arrangement would be undesirable or inadequate. This article sketches an alternative from Clarence Irving Lewis’s works on valuation taken in continuity with John Dewey’s theory of inquiry. This alternative framework assumes epistemic notions of truth and justification, allowing that valuations can be construed in contexts of inquiry and thus as objects of knowledge. (shrink)

We present a study of the linguistic output of the German-speaking writer Robert Walser using Natural Language Processing (NLP). We curated a corpus comprising texts written by Walser during periods of sound health, and writings from the year before his hospitalization, and writings from the first year of his stay in a psychiatric clinic, all likely attributed to schizophrenia. Within this corpus, we identified and analyzed a total of 20 linguistic markers encompassing established metrics for lexical diversity, semantic similarity, and (...) syntactic complexity. Additionally, we explored lesser-known markers such as lexical innovation, concreteness, and imageability. Notably, we introduced two additional markers for phonological similarity for the first time within this context. Our findings reveal significant temporal dynamics in these markers closely associated with Walser’s contemporaneous diagnosis of schizophrenia. Furthermore, we investigated the relationship between these markers, leveraging them for classification of the schizophrenic episode. (shrink)

The philosopher Jorge J. E. Gracia engages fifteen prominent scholars on race, ethnicity, nationality, and Hispanic/Latino identity in the United States. Their discussion joins two distinct traditions: the philosophy of race begun by African Americans in the nineteenth century, and the search for an understanding of identity initiated by Latin American philosophers in the sixteenth century. Participants include Linda M. Alcoff, K. Anthony Appiah, Richard J. Bernstein, Lawrence Blum, Robert Gooding-Williams, Eduardo Mendieta, and Lucius T. Outlaw Jr., and their dialogue (...) reflects the analytic, Aristotelian, Continental, literary, Marxist, and pragmatic schools of thought. These intellectuals start with the philosophy of Hispanics/Latinos in the United States and then move to the philosophy of African Americans and Anglo Americans in the United States and the philosophy of Latin Americans in Latin America. Gracia and his interlocutors debate the nature of race and ethnicity and their relation to nationality, linguistic rights, matters of identity, and Affirmative Action, binding the concepts of race and ethnicity together in ways that open new paths of inquiry. Gracia's Familial-Historical View of ethnic and Hispanic/Latino identity operates at the center of each of these discussions, providing vivid access to the philosopher's provocative arguments while adding unique depth to issues that each of us struggles to understand. (shrink)

ResumoEste artigo propõe elucidar a relação entre a cibernética e a mecanologia na obra de Simondon, considerando suas duas teses de doutorado e a entrevista concedida em 1968 a Jean Le Moyne, a pedido do Ofício do Filme do Québec, no Canadá, ao longo da qual é predominante o uso de "mecanologia", em contraste com as teses, onde sofre a concorrência dos vocábulos "alagmática" e "organologia", ficando o termo "cibernética" na penumbra. A cibernética é celebrada na França em 1962, no (...) contexto dos famosos Colóquios de Royaumont, quando Norbert Wiener foi homenageado e a cibernética ocupou toda a cena, com a participação ativa de Simondon na organização do evento. Essa situação leva os estudiosos a interrogar-se pelo destino do termo "cibernética" em sua obra, caso estivesse em jogo a segunda cibernética, em vez da primeira, e que só veio a lume mais tarde. Mais do que o interesse historiográfico do assunto, o artigo pretende suscitar um interesse epistemológico na filosofia da tecnologia. O desafio é lançar luz sobre a questão ainda por demais obscura acerca das relações entre a tecnologia, a engenharia e a ciência.This article aims to clarify the relationship between cybernetics and mechanology in Simondon's work, considering his two doctoral theses and the interview he gave in 1968 to Jean Le Moyne, at the request of the Quebec Film Office in Canada. In this interview the use of "mechanology" is predominant, in contrast with the theses, where it suffers from competition with terms such as "allagmatics" and "organology", leaving the term "cybernetics" in the shade. Cybernetics is celebrated in France in 1962, in the context of the famous Royaumont Colloquia, when Norbert Wiener was honored and cybernetics occupies the whole scene, with Simondon's active participation in the event organization, This situation leads experts to question the fate of the word "cybernetics" in his work, in the case the second cybernetics was at stake, instead of the first one, but that only came to light later. More than a subject of historiographical interest, the article aims to evoke an epistemic interest in the philosophy of technology. The challenge is to shed light on a question that still remains obscure: the relationships among technology, engineering and science. (shrink)

Kniha až na dva eseje zahrnuje diskusní příspěvky a referáty. Pojednávají o budoucnosti filosofie, malých divadelních formách, antropologických předpokladech moderní kultury, posuzování modelu člověka v dramatickém díle.

ABSTRACT Neurath’s scientific utopianism is the proposal that the social sciences should engage in the elaboration, development, and comparison of counterfactual scenarios, the ‘utopias’. Such scenarios can be understood as centerpieces of scientific thought experiments, that is, in exercises of imagination that not only promote conceptual revision, but also stimulate creativity to deal with experienced problems, as utopias are efforts to imagine what the future could look like. Moreover, utopian thought experiments can offer scientific knowledge to inform political debates and (...) decisions, contributing to the shaping of society. This essay reconstructs a historical event as an example of Neurath’s utopianist methodology. In the late 1970s and early 1980s, a scientific and political commission appointed by the Western German Parliament devised and compared four scenarios for future energetic-economic policies. Conclusions of the commission informed political decisions that put Western (later reunified) Germany in a route towards becoming a green industrial power. A fundamental part of the commission’s work involved an appeal to imagination, allowing for the characterization under Neurath’s methodology. (shrink)

Recent anti-governmental social movements in countries of former Yugoslavia have awakened the spirit of contention which had been dormant for almost two decades. The overwhelming economic deprivation, accompanied by the massive violation of basic human rights of the citizens, urged the challengers to take the streets.This paper is focused on comparison of two movements, the “Citizens for Macedonia” movement in the Republic of Macedonia and the “Bosnian Spring” in Bosnia and Herzegovina, highlighting the role and influence of movements on the (...) occurrence of policy outputs which articulated claims put forward by social movement organizations as well as other movement actors in the two respective countries. The analysis will be conducted taking into consideration specific social movement related variables like forms/types of claims-making and repertoires of action, as well as wider political process factors such as repression by state actors, and the attitude of allies and opponents of the movements.Regarding the methodological approach, we will apply a mixed comparative research design, with variation both on side of the independent and the dependent variables. Since the outcomes of the movements are already tangible, we will also apply elements of process tracing methodology, reconstructing the events as much as possible. My primary data collection tools encompass in-depth interviews with four specific categories of interviewees as well as thorough document analysis referring to the policy outputs. (shrink)

The article deals with the financing of investment projects by the World Bank, especially the rehabilitation of hydropower plants. It is noted that cooperation with Ukraine World Bank launched since 1992. The World Bank develops and finances projects at the request of the Government of Ukraine. After evaluating the project and the terms of the loan are following the negotiations, the approval of the Board of Directors and the signing of the agreement. The funds of the World Bank in Ukraine (...) are on the system of financing and investment projects. The content system projects is to change the conditions and rules of certain sectors of the public administration or industries. The aim of the investment projects is the technical reconstruction of some existing businesses a particular industry or region, creating new companies or provide funds to replenish the working capital of enterprises. This clearly defined list of goods, services and works to be procured through the World Bank loan. The paper conclusions on the results of the project of rehabilitation of hydropower plants. SuccessinitiatedenergyreforminUkraineislargelydeterminedbytheefficiencyoftheinvestmentpolicy, including attracting loans from international financial organizations. On receipt of credit, including the World Bank, depend on the possibility of upgrading technologically obsolete and worn-out fixed assets of the energy sector and problems olving reduce country's energy dependence, improve energy efficiency and reduce the impact on the environment. In turn Hydropower Rehabilitation project funding by the World Bank Ukraine will ensure uninterrupted operation of hydropower plants and have a positive impact on the environmental and energy security. (shrink)

How do we relate globalisation to other types of mondialisation, such as communications and economics? The answer should be: any globalisation should be motivated by the general interest of humanity and striving to that aim. In practice, this means that international protection of human rights and environmental rights need not only jurisdictional but also, above all, ethical standards. Without it, a conflict between different types of globalisation could become damaging, almost dangerous. The very idea of the global village that has (...) so well explained the phenomenon of mondialisation can assist in solving the problems that need to be addressed. One of the features of each village is the intense connection among the inhabitants. That phenomenon is now present globally, which is the essence of globalisation. That implies a global responsibility that must be implemented on the one hand by communities and the other by individuals, especially those who serve in the service of community — politicians. The crucial question arises, “How to define the responsibility of one and the others?” It is evident that at the top of the pyramid, there are major planetary problems whose solutions require the cooperation of all nations and countries. The straightforward phrase “Think globally, act locally”, expresses the rule of the fundamental game of the global world and its diversity — a possible ethic of sustainable development. (shrink)

In a attempt to get around a certain misunderstanding that prevents us from seeing the similarities between Alain Badiou’s theory of the subject and the Wertkritik (or critique of value), we try to point out how in these two conceptual approaches there is an absolute refusal of the capitalist system. In order to do so, it was necessary to elucidate how the resumptions of Marx’s thought that are materialized, in one case, in the theorization carried out by Badiou and, in (...) the other, by the critique of value, although they do not coincide with each other, do not truly prescribe an exclusion of each other. (shrink)

Many philosophers have been appointed to top-level political positions during Chile's modern history. What makes Chilean philosophers unique in the context of Latin America and beyond, is that they have developed a sophisticated rationale for both their participation and withdrawal from politics. All along, philosophers have grappled with fundamental problems such as the role of religion and politics in society. They have also played a fundamental role in defining the nature and aims of higher education. The philosophers' production constitutes a (...) substantial, albeit largely unknown, portion of the intellectual history of Chile and Latin America. This book describes in detail the evolution of philosophical work in Chile, and pays close attention to the relationship between philosophical activity and contemporary social and political events. Various Chilean philosophical sources are discussed for the first time in the literature on Chilean ideas. The work of such intellectuals as Andres Bello, Valentin Letelier, Enrique Molina, Jorge Millas, Juan Rivano, Juan de Dios Vial Larrain, and many others is examined in relation to the principal political and educational issues of their time. The book also develops a distinction between the two main currents of Chilean philosophy, namely, a "professionalist" current that seeks the independence of the field from social and political involvements, and a "critical" current that seeks to relate philosophical activity to national realities. (shrink)

After unsuccessful attempts to form Liberal-Socialist and tripartite cabinets, another center-left cabinet was made. It was the first cabinet headed by Flemish Christian-Democratjean-Luc Dehaene. Not commanding a two-thirds majority in Parliament, the constitutional reform agenda was referred to a community-to-community dialogue which resulted in an overall constitutional reform agreement concluded in the fall.Not much action was taken on the budget deficit, and the cabinet's reliance on new taxes led to tension inside the coalition, with the CVP insisting on additional spending (...) cuts. Labor and management reached agreement on a 1993-94 national inter-industry accord for the private sector.The cabinet decided to abolish conscription, and the armed farces were involved in UN-sponsored peacekeeping missions in ex-Yugoslavia and Somalia.In Parliament, there was a large majority in favor of the Maastricht Treaty. (shrink)

In 1996, Belgian politics centered around three major issues: the jobs contract, the 1997 budget and political fallout of the Dutroux affair.During the first months of the year, Prime Minister Dehaene attempted to win support for a comprehensive jobs contract, but the draft agreement was turned down by the Socialist trade union militants. Nevertheless, the measures contained in the agreement were later implemented by the cabinet, without the consent of the employers and organized labor. Together with adjustments made to the (...) social security system and implementation of budgetary measures needed to reach the conditions set by the EU for joining the Economic and Monetary Union, the jobs contract was implemented by means of special powers. The cabinet obtained these special powers from Parliament before the summer recess. After the summer, as a result ofthe Dutroux alfair, the cabinet dealt with legal reform, in the process trying to quell tensions arisen among the law enforcement agencies. (shrink)

Whereas the Belgian politica! world had planned a calm transitional political year leading to the January 1992 general elections, 1991 was a year of political turmoil resulting in the resignation of the cabinet and genera! elections. The Martens VIII cabinet had planned to implement the third and final phase of its constitutional reform package. However, in the fall tension rapidly rose inside the cabinet. White the majority parties were positioning themselves for the next elections, a row over arms sale licences (...) caused the fall of the cabinet. First the Volksunie left, but only a few days later Prime Minister Martens had to submit the resignation of bis cabinet. In the ensuing genera! electiOns, all the traditional parties lost ground except PW and the losses were particularly severe for the Flemish Christian Democrats and the Flemish Socialists. Winners were the ultra-right Vlaams Blok in Flanders and the ecologists in Francophone Belgium. (shrink)

In 1990, Belgium's domestic political agenda was overshadowed by international events. Developments in Zaire, Rwanda and especially in the Gulf often forced Belgian political leaders to set aside their domestic preoccupations. On the pending constitutional reform issues no substantial progress was made. At the end of 1990, many bills dealing with economic issues awaited parliamentary approval. In the fall, labor and management reached a nationwide inter-industry collective bargaining agreement and a new pension bill was adopted by Parliaiment.

The center-left Martens VIII cabinet, which had taken office in May 1988 following the longest political cricis in Belgian history, continued in 1989 implementation of its constitutional reform program. The European elections had no domestic impact, but during the campaign the focus was once again on the burning immigration issue. Meanwhile, abortion liberalization caused tension inside the majority. In foreign affairs, the focus was on normalization of relations with Zaire.

In 1987 the Martens center-right cabinet had to resign over the perennial Fourons issue. The many painstakingly reached compromises each time met strong opposition from the Francophone Social Christian Party and its ministers on the government benches. Once the government resignation accepted by the King, Parliament was dissolved and elections were held. They resulted in a Socialist victory, and a personaldefeat for Prime Minister Martens. In the election aftermath, a cabinet of Christian Democrats and Socialists became more likely.Because of the (...) Fourons issue, the Cabinet found hardly time to address their other issues, and many of the decisions it reached were never implemented because of the government crisis ; e.g. the tax reform plan.The most important decision in the international field was the sending of minesweepers to the Gulf. (shrink)

This article examines the contributions made towards eugenic thought in the late nineteenth and early twentieth centuries by Havelock Ellis . Ellis was a significant social reformer who worked on the problems of sexuality from a scientific–naturalist secular perspective. In the later phases of his work, after he had completed much of his writing on sexuality, Ellis concentrated on issues of feminism and eugenics—problems he thought were interlinked. In this paper, I integrate his ideas about these subjects, and consider the (...) ways in which Ellis and other liberal social reformers created a ‘eugenic subject’ in order to frame their arguments about social problems. (shrink)

Neste artigo apresentamos as propostas de Otto Neurath para o problema da unidade da ciência. Conhecido integrante do Círculo de Viena, Neurath defende que a ciência deve ser unificada por meio da chamada concepção de mundo científica, uma orientação ou atitude em relação ao mundo e aos problemas que é característica da ciência. Neste artigo apresentamos o caráter social dos projetos de Neurath, como o da Enciclopédia Internacional da Ciência Unificada. Contrastamos a proposta de Neurath com a crítica pós-modernista da (...) abordagem contextualizada dos estudos sobre a ciência. Essa crítica parte de estudos de comunidades científicas e, em geral, apresenta a conclusão de que não há um fator que unifique a ciência. O termo "ciência" denotaria apenas uma coleção de atividades sem características relevantes em comum. A comparação feita mostra que a posição de Neurath é compatível com a abordagem contextualizada, apesar de defender a unidade da ciência. Por fim, avaliamos o aspecto político da proposta de Neurath diante da crítica pós-moderna e notamos que as ideias do Círculo de Viena e da Enciclopédia podem ser valiosas nos dias de hoje. This paper discusses Otto Neurath's proposal for the problem of the unity of science. This author, a well-known member of the Vienna Circle, proposes that science is to be unified by the so-called scientific world-conception, a characteristic orientation or attitude of science towards the world and the problems it deals with. In this paper, emphasis is given to the social aspect of Neurath's projects, as found, for instance, in the International Encyclopedia of Unified Science. It contrasts Neurath's proposal with the post-modernist criticism, developed in the contextualized approach to science studies, that stems from studies of scientific communities and, in general, presents the conclusion that there is no unifying factor for science. The term 'science' would then denote just a collection of activities with no relevant common characteristics. The comparison made shows that Neurath's position is compatible with the contextualized approach, even though he defends the unity of science. Finally, the political aspect of Neurath's proposal is evaluated in the light of the post-modernist criticism, and it is pointed out that the ideas of the Vienna Circle and the Encyclopedia might be valuable nowadays. (shrink)

Este artigo discute a relação entre filosofia da ciência e filosofia da educação a partir do texto de John Dewey Unity of Science as a Social Problem. Dewey propõe que o problema da unidade da ciência seja trabalhado de um ponto de vista não apenas epistemológico, mas também social. Isso é porque nosso entendimento sobre a ciência influencia a educação. A proposta de Dewey é discutida em relação às considerações de filósofos da ciência recentes, como Peter Galison e Paul Feyerabend, (...) de que a ciência não deve ser concebida como um todo unificado. (shrink)

This Special Issue brings a selection of peer-reviewed papers that were presented at the 12th Principia International Symposium: Models and Modeling in the Sciences, Florianópolis, Brazil, online, August 2021. In this preface, the chair and the secretary of the organizing committee comment the symposium's context and briefly present the issue.

Otto Neurath and John Dewey share the understanding that science must have a prominent role in democratic social reform. This is a common aim that brought logical empiricism and pragmatism together in the first half of the 20th century, but there are differences between the two stances. On the one hand, Neurath sees a limitation of scientific knowledge, considering that it cannot determine decisions to be taken in the course of social reform. Such decisions, in the logical empiricist view, are (...) a matter of politics. On the other hand, Dewey sees a continuity among all forms of inquiry and, therefore, the conclusions of valuational inquiry are analogous in their epistemic claims to the conclusions in factual (natural or social inquiry). This paper investigates the divergence and concludes that pragmatist continuity of inquiry is set in a psychological context that disregards a difference in objectivity between factual and valuational inquiry. (shrink)

El propósito de este trabajo es analizar la crítica foucaultianade la gubernamentalidad liberal como marco de racionalidad de la biopolítica. Particularmente, colocaremos el foco de la lectura en la problematización que Foucault despliega respecto de la formación de la economía política en tanto saber estratégico de la racionalidad liberal. Por ello, en el primer apartado, nos detendremos en la grilla de la gubernamentalidad como herramienta que la permite a Foucault elaborar una arqueo-genealogía de las formas de objetivación. Luego, dirigiremos la (...) lectura hacia la arqueo-genealogía de las formas de objetivación inmanentes a la constitución del discurso de la economía política en tanto saber estratégico de la gubernamentalidad liberal. (shrink)

El propósito de este trabajo es indagar la crítica foucaultiana del neoliberalismo desarrollada en las conferencias que Michel Foucault dictó en el Collège de France en 1979. En dicho curso, el filósofo francés propuso un abordaje crítico de la economía política al que denominó crítica política del saber. Por lo tanto, el foco de este artículo es la crítica política del saber económico que despliega en el curso mencionado. Investigación arqueo-genealógica en la que el neoliberalismo no es estudiado ni como (...) una ideología ni como una teoría económica, sino como una racionalidad gubernamental. (shrink)

A lo largo del presente artículo se pretende analizar la problematización foucaulteana de las ciencias humanas elaborada en el contexto de sus trabajos sobre biopolítica y gubernamentalidad. En ese sentido, la biopolítica y la gubernamentalidad en cuanto tales no constituyen el objeto de nuestra indagación, sino que más bien es a través del abordaje foucaulteano de dichas problemáticas que buscaremos revisar su lectura respecto de los saberes acerca de “lo humano”.

El objeto de este artículo consiste en señalar las relaciones entre el método, la física y la metafísica cartesianas. Puede afirmarse que a partir de la idea básica de como debe ser la ciencia, Descartes concibe su física y fija el mecanicismo como la condición de toda explicación y de toda inteligibilidad; de estos se siguen las consecuencias metafísicas concernientes a la distinción del cuerpo y del alma y los temas finales de su unión que tanta claridad aportan sobre los (...) sentimientos y la moral. (shrink)

Endosomes, which comprise a diverse population of membrane vesicles and tubules, sort proteins and lipids to various cellular destinations. The organization and functions of these pleiomorphic cellular organelles have been extensively studied. Matsuo et al.1 now provide new exciting evidence on the role of lysobiphosphatidic acid (LBPA), a resident phospholipid of internal vesicles of the late endosome, in the control of membrane invagination and endosome biogenesis. In vivo, LBPA functions are controlled by the adaptor protein Alix and depend on pH (...) gradients along the endosomal compartments. BioEssays 26:604–607, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

Soluble components of Notch signalling can be applied to manipulate a central pathway essential for the development of metazoans and often deregulated in illnesses such as stroke, cancer or cardiovascular diseases. Commonly, the Notch cascade is inhibited by small compound inhibitors, which either block the proteolysis of Notch receptors by γ‐secretases or interfere with the transcriptional activity of the Notch intracellular domain. Specific antibodies can also be used to inhibit ligand‐induced activation of Notch receptors. Alternatively, naturally occurring endogenous inhibitors of (...) Notch signalling might offer a specific way to block receptor activation. Examples are the soluble variants of the canonical Notch ligand Jagged1 and the non‐canonical Notch ligand Dlk1, both deprived of their transmembrane regions upon ectodomain shedding, or the bona fide secreted molecule EGFL7. We present frequently used methods to decrease Notch signalling, and we discuss how soluble Notch inhibitors may be used to treat diseases. (shrink)