Child Labour in Kashmiri Society: A Socio-human Rights Study The Constitution of India guarantees fundamental rights and the full freedom to enjoy childhood. In spite of that millions of children are being put to arduous work for short and narrow gains. By 1989, the standards concerning children were brought together in a single legal instrument agreed to by the international community. It unambiguously spelt out the rights to which every child is entitled, regardless of place of birth, descent, sex, religion, (...) or social origin. A number of aspects, such as gender, family background, cultural acceptance, issues of health and recreation, the legal aspect and so on, have been covered. The life worlds of working children, legal protection to children from exploitation and the human rights perspective of child labour is the main focus of this article. (shrink)

Work on Nyaya philosophy; includes Siddhāntamuktāvalī autocommentary and Dinakarī of Dinakarabhaṭṭa, 18th cent.

Flavin‐containing monooxygenases (FMOs), traditionally known for detoxifying xenobiotics, are now recognized for their involvement in endogenous metabolism. We recently discovered that an isoform of FMO, fmo‐2 in Caenorhabditis elegans, alters endogenous metabolism to impact longevity and stress tolerance. Increased expression of fmo‐2 in C. elegans modifies the flux through the key pathway known as One Carbon Metabolism (OCM). This modified flux results in a decrease in the ratio of S‐adenosyl‐methionine (SAM) to S‐adenosyl‐homocysteine (SAH), consequently diminishing methylation capacity. Here we discuss (...) how FMO‐2‐mediated formate production during tryptophan metabolism may serve as a trigger for changing the flux in OCM. We suggest formate bridges tryptophan and OCM, altering metabolic flux away from methylation during fmo‐2 overexpression. Additionally, we highlight how these metabolic results intersect with the mTOR and AMPK pathways, in addition to mitochondrial metabolism. In conclusion, the goal of this essay is to bring attention to the central role of FMO enzymes but lack of understanding of their mechanisms. We justify a call for a deeper understanding of FMO enzyme's role in metabolic rewiring through tryptophan/formate or other yet unidentified substrates. Additionally, we emphasize the identification of novel drugs and microbes to induce FMO activity and extend lifespan. (shrink)

Verse treatise, with autocommentary and supercommentaries, on the basic concepts and epistemology of Nyāya and Vaiśeṣika schools in Indic philosophy.

Scandals in companies such as Enron have been a source of great concern in the last decade. The events that led to a global financial crisis in 2008 have heightened this concern. How does one account for executive behaviors that led to such a crisis? This article argues that a conjunction of motive, means, and opportunity creates ‘an ethical hazard’ making questionable executive decisions more probable. It then suggests that corporate unethical behavior can be minimized by creating a process to (...) identify and remove such ethical hazards, and by appointing an ‘ethical hazards marshal.’. (shrink)

Contributed articles on self-realization.

Classical verse work on the fundamentals of Nyāya and Vaiśeṣika schools in Hindu philosophy.

Compendium of Indian epistemology and logic.

International health-related research on human subjects entails unique ethical responsibilities and difficulties. Often, these difficulties are augmented by the lack of a local ethical review infrastructure. In a recent cross-national study conducted by us, three critical components of ethical regulation were identified—external oversight, local oversight and subject involvement—and integrated into the study design. These three concepts are outlined and established as an important aspect of ensuring ethical coherence in the local context, particularly when reviews by the local institutional review boards (...) cannot practically be obtained. The three levels of ethical oversight identified are suggested to be the framework within which future field studies on human subjects are developed and a standard for maintaining ethical rigorousness in research on humans. (shrink)

This study attempts to fill in two research gaps in the extant literature concerning the ecosystem for social innovation in the context of emerging market economies such as India. The study first attempts to assess the potential of corporate social responsibility (CSR) in not-for-profit entities such as technology business incubators (TBIs) to stimulate social innovations in the prevalent ecosystems in emerging markets. Further, using a random-effects Tobit model, the study examines the characteristics of firms that spend higher percentages of CSR (...) expenditure on not-for-profit TBIs/societies/trusts in India. The study provides policy suggestions to create an entrepreneurial ecosystem for promoting social innovation in emerging markets such as India. (shrink)

Pashmina is one of the most luxurious and finest fibres in the world. It is a special kind of wool obtained from Cashmere goats. Counterfeiting Pashmina is becoming a prevalent malpractice because of limited supply, expensive pricing and high demand in western markets. Presently, there is a lack of a low-cost and easily available approach for distinguishing authentic Pashmina apparels from other similar-looking products. Because of technological advances and cost reductions in digital image processing, we have been able to implement (...) a variety of image recognition systems on a practical level. In this study, we propose a deep learning model PashmNet for identification of Pashmina fabric using transfer learning. The technique proposed herein classifies Pashmina and non-Pashmina images accurately with classification accuracy of 97.4%. (shrink)

Contributed research papers on Indic philosophy.

Classical commentary on Nyāyasūtra of Gautama, aphoristic work on Nyaya philosophy.

The relatively simple central nervous system (CNS) of the Drosophila embryo provides a useful model system for investigating the mechanisms that generate and pattern complex nervous systems. Central to the generation of different types of neurons by precursor neuroblasts is the initial specification of neuroblast identity and the Drosophila segment polarity genes, genes that specify regions within a segment or repeating unit of the Drosophila embryo, have emerged recently as significant players in this process. During neurogenesis the segment polarity genes (...) are expressed in the neuroectodermal cells from which neuroblasts delaminate and they continue to be expressed in neuroblasts and their progeny. Loss-of-function mutations in these genes lead to a failure in the formation of neuroblasts and/or specification of neuroblast identity. Results from several recent studies suggest that regulatory interactions between segment polarity genes during neurogenesis lead to an increase in the number of neuroblasts and specification of different identities to neuroblasts within a population of cells. BioEssays 21:472–485, 1999. © 1999 John Wiley & Sons, Inc. (shrink)

In this paper, we propose a general copula approach to accommodate non-normal continuous mixing distributions in multinomial probit models. In particular, we specify a multivariate mixing distribution that allows different marginal continuous parametric distributions for different coefficients. A new hybrid estimation technique is proposed to estimate the model, which combines the advantageous features of each of the maximum simulated likelihood inference technique and Bhat’s maximum approximate composite marginal likelihood inference approach. The effectiveness of our formulation and inference approach is (...) demonstrated through simulation exercises and an empirical application. (shrink)

The European Legacy, Volume 17, Issue 3, Page 400-401, June 2012.

Animal personality refers to the consistency of variation in behavior among individuals which may be the driving force behind variations in complex behaviors as well. Individual personality could predict how well an organism would perform in behavior and cognition related tasks, as well as survive and thrive in its environment. Therefore, we would expect inter-individual variations in many behaviors, which would persist even if habituation to the experimental setup occurs, which generally results in convergence of behavior. Our study used wild-caught (...) zebrafish from three natural habitats with differing ecological regimes, to understand how consistency and repeatability in specific traits such as boldness, exploration, and spatial ability varies across and within populations even when habituation causes change in behavior. We found that the extent of individual variation differs between populations, with dynamic habitats showing similar repeatability. This indicates that habitat conditions are important drivers of individual variation in addition to other factors, such as sex or size of individuals within populations. Although we found that sex and size played an important role within some populations for some behaviors, in others, the variation was likely caused by other factors, for which we have not accounted. This study underlines the importance of studying inter-individual differences as the phenomenon that underpins multiple behavioral traits and explains the possible role of environmental and inherent factors that drive these differences. (shrink)

Dissipative structures exist at all scales, systems, and at different levels of complexity. A thermodynamic theory integrating simple and complex DS is introduced, which addresses existence of growing/decaying DS based on their entropy analysis. Two entropy-based dimensionless ratios are introduced, which explain negentropy-debt payment and existence of DS with growth or decay. It is shown that excess negentropy debt payment is needed and beneficial for growing DS; but for decaying DS, it hastens its approach to perish and is counter-productive. Growing (...) complex DS tend to pay lower negentropy debt to their surroundings, due to involvement in other activities enabled by complexity; e.g. mediation for survival that is linked to their mortality. Hence, disorder of complex DS increases, due to which, their growth can be un-sustained, leading to entry in decay-phase in spite of availability of adequate mass-energy in-flows. Proper handling or reduction of complexity enables growth in the direction of ideal growth, which is limited only by availability of adequate mass-energy in-flows. (shrink)

This article seeks to examine the representation of masculinities and femininities in the renowned South Indian drama film The Great Indian Kitchen. The research construes the manner in which the two dominant genders promote and/or modify patriarchal norms within the institution of family. The functioning of women as ancillary members of patriarchy, the interplay between masculinities and femininities, their evolution in contemporary times, etc., are also critically engaged in the paper. The paper argues that the movie The Great Indian Kitchen (...) not only illustrates different masculinities and femininities but also reconstructs the patriarchal family structure which institutionalises gender inequality. It further argues that the movie proposes an alternative image of the family based on gender equality, where men and women live with mutual respect and complementation. (shrink)

Text explaining in accordance to Sanskrit grammar; select usage of words in commentary of Brahmasūtra by Śaṅkarācārya.

Critical study of Nyāyamañjarī of Jayanta Bhaṭṭa, active 850-910, work on Nyaya philosophy.

Sanskrit text with Hindi verse translation of Aṣṭāvakragītā, work on Vedanta philosophy.