Homeobox genes play essential roles in specifying the fates of different cell types during embryogenesis. In Drosophila, the homeotic gene caudal is important for the generation of posterior structures. In the mouse, the caudal homologue Cdx2 has been implicated in directing early processes in intestinal morphogenesis and in the maintenance of the differentiated phenotype. A recent study showed that Cdx2 null mutation was embryonically lethal, whereas Cdx2+/− mice developed multiple intestinal polyps in the proximal colon in addition to developmental defects(1). (...) There are striking phenotypic similarities and differences between Cdx2+/− and other mice predisposed to intestinal neoplasia. The possible role of Cdx2 in human colorectal tumorigenesis is discussed. (shrink)

Based on the Chinese General Social Survey database, this article explores the relationship between income inequality and residents’ subjective well-being from the perspective of inequality of opportunity and inequality of effort. We find that inequality of opportunity has a negative impact on subjective well-being in China, where inequality of effort has a positive impact. Our empirical results are robust for changing the inequality indicators. In the sub-sample studies, consistent conclusions are obtained in rural areas, whereas in urban areas only inequality (...) of effort has a significant impact. The results of mechanism study show that inequality of opportunity decreases residents’ sense of fairness, and inequality of effort increases residents’ sense of fairness, thus affecting their subjective well-being. The results of this study provide a good response to the inconclusive research findings on the impact of income inequality on subjective well-being. (shrink)

Compared to a charging scheduling and management problem characterized by predetermined trip assignment, this study takes bus and driver scheduling into account, and mealtime windows must be guaranteed as one of the major labor regulations. A discretized mixed-integer linear programming model is developed based on a single electric bus route. We aim to obtain fast and high-quality global solutions for this problem, and the model can be easily executed by bus operators by directly invoking an available optimization solver such as (...) IBM ILOG CPLEX. We test our model on a real round-trip bus route. Numerical experiments show that CPLEX takes approximately 6 sec to obtain an optimal solution. The model can not only reasonably arrange daily trips for each electric bus and driver but also effectively determine the optimal charging schedule and management for an electric bus line. Besides, we analyze the sensitivity of the key parameters in the model. With the increase in the drivers’ maximum workload, the drivers’ average idle time decreases by approximately 11.25%. The objective value decreases by approximately 38.71% and 40.04% with increases in the battery capacity and fleet size, respectively, and the objective value increases by approximately 30.06% with the decrease in the initial battery driving range. In addition, we compare the effectiveness of our time discretization modeling method in solving the same case study to that from other similar studies, and the validity of our method can be verified by the calculation time. We also compare the computational efficiency of CPLEX in solving the same case study problem with and without implementing valid inequalities, and the computational efficiency of the valid inequality method is greatly improved. Finally, through the testing of a multiline network, the potential application of the model to a large-scale traffic network is verified. (shrink)

The graph tong同and its associated concepts, such as da-tong (Great tong大同) and xuan-tong (mystic or dark tong玄同), have played important roles in the development of Chinese philosophy. Yet tong has received scant attention from either western or eastern scholarships. This paper is a first attempt to remedy such regret. Unlike usual understandings of tong as sameness or unity, this paper presents a nuanced account from early China, that is, ‘difference to one,’ a definition from the Mozi墨子. (...) This definition can be supported from etymological, textual, and lexical evidence. ‘Difference to one’ should not be solely attributed to a Mohist understanding; it in fact represents a common understanding of tong across philosophical streams in early China. This nuanced account provides new insights into the concept of tong in early philosophical texts, and furthermore breaks solid grounds for further studies of tong and its associated concepts. (shrink)

Past interpretations of the debate between Confucian meritocrats and Confucian democrats tend to center around abstract discussions of meritocratic versus democratic values. Yet, given the difficulties involved in settling on a common definition of “democracy” or “meritocracy,” such abstract discussions often end up talking past each other. In this article, I seek to offer a more precise framing of the debate by surveying the preferred institutional arrangement of one Confucian democrat, Sungmoon Kim, and that of two Confucian meritocrats, Daniel Bell (...) and Tongdong Bai. What I find is that contrary to the claim made by Kim’s theory of pragmatic Confucian democracy, the electoral representative government he favors does not enjoy a legitimacy premium over the kind of hybrid regime envisioned by Bell or Bai under pluralistic societal circumstances. I further demonstrate that it is also difficult for Confucian democrats to justify electoral representative government through either the Confucian ideal of political relationship marked by the public’s willing endorsement of their rulers, or a notion of political equality reconstructed from Mencius’s inclusionary ideal of sagehood. (shrink)

The Philosophical Forum, Volume 53, Issue 1, Page 47-61, Spring 2022.

Im Jahr 2002 wurde seitens der chinesischen Regierung die Forderung der Entfaltung der exzellenten nationalkulturellen Tradition aufgestellt. Nach einem Kultur-Gipfelforum mit dem Hauptthema "Globalisierung und die Chinesische Kultur" unter der Leitung von bedeutenden Wissenschaftlern wie Ren Jiyu, Ji Xianlin u. a. im Jahre 2004 stieg die Wertschätzung des Konfuzianismus als Kernbestandteil "exzellenter Nationalkultur". Folglich wächst heutzutage das Interesse an konfuzianischen Klassikern wieder, vorwiegend für Lunyu. Infolge des gestiegenen Interesses versuchten Autoren im neuen Zeitalter in China, diesen Klassiker neu auszulegen. Am (...) bekanntesten wurden die Bücher von Yu Dan. Einflussreich waren auch die Interpretationen von Li Ling und He Xin. Folglich werden diese neuen Interpretationen hier als Formen der Rekonstruktion der konfuzianischen Tradition behandelt und in drei Arten klassifiziert: volkstümlich, populärwissenschaftlich sowie akademisch. Die Theorie dieser Forschungsarbeit stützt sich auf dem Traditionsbegriff. Infolgedessen wird die Tradition aus der neologistischen Perspektive, im alltagssprachlichen Bezug, nach politischem Verständnis und im wissenschaftlichen Gebiet analysiert. Dann wird die Tradition als ein Konstrukt definiert, das aus über Generationen weitergegebenen Kulturelementen besteht. Daher wird der Konfuzianismus sowohl als ein bedeutsames Element der chinesischen Tradition als auch als eine konfuzianische Tradition betrachtet. Die Forschung wählt drei einflussreiche Interpretationen dieser Art aus, um einen kritischen Zugang zum Prozess der Neuschaffung von "Tradition" im gegenwärtigen China zu finden. Die Interpretationen scheinen die Nachfrage und Erwartungen von Gesellschaft und Politik gleichermassen zu befriedigen und können daher als Linsen dienen, mittels derer wichtige soziale und politische Anliegen und Entwicklungen Chinas seit der Jahrtausendwende in Augenschein genommen werden können. (shrink)

Richard, a sixty‐seven‐year‐old man, has been admitted to Midtown University Center for difficulty breathing. He has a significant medical history that includes pulmonary fibrosis and subsequent heart failure, and he depends on supplemental oxygen to breathe. Upon admission and after discussing his prognosis with his family and doctors, Richard decided to sign a do‐not‐resuscitate order stating that if his heart stops or he stops breathing, he does not want to undergo cardiopulmonary resuscitation or other life‐sustaining measures. On his third day (...) in the hospital, the nurse practitioner who is caring for Richard notices that his breathing is becoming more labored and that his blood pressure is steadily dropping. She thinks he requires closer observation and treatment in the cardiac intensive care unit. Dr. P, the physician in the intensive care unit at the time, Dr. P does not want to accept Richard into the CICU because of his prognosis and his DNR order. He believes that Richard should be cared for on a regular hospital floor, and that the last bed in the CICU should be held for its intended user—a patient suffering a life‐threatening heart attack who requires intensive care. Should Richard be admitted to the CICU? (shrink)

本书是一本关于中国隋唐、明代时期理学研究的书, 内容包括有河东学派的地域渊源、河东学派形成的社会原因和思想渊源等六章.

本书从深层次上去把握中国古代尚清审美趣味的实质性意义及其审美价值,并从宏观上阐明了其产生与发展、演化的历史过程及其相应的社会基础与意识形态根源。.

本书分上下两篇。上篇论述了中国传统文化的根本精神、和谐精神的基本特征及其评价、和谐精神产生的基本条件、和谐精神的三大内涵;下篇系统阐述了儒家、道家、禅宗的和谐美学,并对其进行了比较。.

本书介绍了中国式的超越和西方文化超越的神学论;理性、关联性与过程语言;中国的性别歧视观;儒家思想与实用主义;儒家民主主义等内容。.

本文集收入“传统道德文化的继承与批判”、“中国传统文化的现代化意义”、“关于中国传统道德和文化的几个问题”等文章61篇。.

中道思想在我国源远流长, 自上古尧、舜开始, 一脉相承于禹、汤、文、武、周公、孔子、孟子、以及汉唐、宋、明、清乃至近代, 延续了几千年, 有着极为丰富的内涵, 可以说, 历代社会的治乱兴衰, 均逃不出执政者的得中与失中的因果规律. 因此, 认真探索一下中国古代的中道即中和思想的产生与发展及其在各方面的表现形式, 不仅具有重要的学术价值, 同时也对于当今构建和谐社会具有重大的现实意义.

本书介绍了“三个代表”重要思想是新世纪“指导自己前进的真理”;“三个代表”重要思想是对马克思主义的新发展;“三个代表”重要思想的科学内涵和内在关联;继续为实现党的基本路线和历史任务面奋斗等。.

這是一本醫者的手札,道盡了生命的現實,記述著臨終或重病的現象和生命的極限,並揭示愛與珍惜生命的道理,除了對患病者本身在面臨驟變時的心態調適有幫助之外,也是與讀者做一番如何克服感情與生命的最痛的對話.

◎孔子為何周遊列國？因為沒有一個國君想用儒家治國，他只好到處教書遊說。 ◎秦國用法家統一天下，漢高祖劉邦用道家蓄積國力，直到漢武帝登基，儒家才被注意。 ◎儒學為何從沒人理，轉眼變治國工具？這得從董仲舒的「解釋」說起。 ◎儒學就像作業系統，幾千年來更新過四次版本，孔子的儒學不等於現在的儒學。 作者馬大勇，清華大學、上海交通大學國學特聘教授。 曾被推舉為最受歡迎的中文教授。 在本書中，他將儒家文明分為五個時期： 孔子奠基期、孟子成熟期、兩漢經學期、宋代理學期和明代心學期。 解析儒家思維是如何像電腦作業系統一樣，歷經四次的版本更新， 從原本的中庸之道、民為貴、君為輕的民主思想， 一步步變成君權神授，天人感應， 成為各朝代帝王穩固皇權的最佳推手。 就此儒學變成帝王學，開啟了千年以來人民為皇權奴隸的中央集權體制。 ◎孔子的儒學，是教你如何當君子 《論語》中，仁字出現了104次，禮字出現74次， 孔子的重要理念「中庸之道」，更成為宋元以後科舉考試的必讀書。 這個具有人道主義的思維，為何不被當時的統治者如春秋諸侯或秦國採納？ 因為亂世中，做君子的好處太少，當小人能得到的利益比較多。 ◎孟子是民主思想的啟蒙者，但被後代皇帝刪掉了 孟子思想的最大亮點就是「民為貴，社稷次之，君為輕」， 這套民主思維後來為何會消失？ 因為明太祖朱元璋看到「君為輕」三個字，就把《孟子》一書狠狠摔地上， 刪節版《孟子》就此誕生，往後一百年，學生學到的孔孟儒學知識都是不完整的。 ◎因為董仲舒的「特殊解釋」，從此百家遭罷黜，皇帝獨尊儒術 秦國用法家思想滅六國一統天下，漢高祖劉邦用道家治國，修生養息， 兩大皇權都對儒家思維沒興趣，直到漢武帝劉徹時期， 董仲舒為了拍皇帝馬屁，重新解釋，儒術從此轉化帝王術。 他口中的儒教，跟孔孟闡述的儒學，哪裡不一樣？差在造神。 ◎宋元明清重新詮釋儒學，想當官者必讀四書 宋、元之後，孔子的《中庸》又重新被提起， 因為它教你用大學之道維持國家秩序。 儒學家朱熹更讓《四書集注》成為為官者的必讀聖書。 至於為什麼是宋朝與明朝，跳過了大唐盛世？ 因為東漢黨錮之禍殺害許多知識分子，儒家文化走向低谷； 南北朝興盛佛教；至於唐朝則儒、釋、道並重。 直到韓愈寫的《原道》為儒家文明打下基礎，在宋代發揚光大。 打天下靠武力，龍椅要坐穩就靠統治， 儒家思想如何經過五階段改造，從民主思維變中央集權， 而且延續千年「至今」不墜。 本書特色 儒學為何從沒人理，轉眼變治國工具？這得從董仲舒的「解釋」說起。 孔子的儒學，如何經過五階段改造，從民主思維變中央集權。 名人推薦 淡江大學中文系教授／高柏園.