There seems to exist a dilemma in the literature as to the correct relativistic formula for the Sagnac phase-shift. The paper addresses this issue in the light of a novel, kinematically equivalent linear Sagnac-type thought experiment, which provides a vantage point from which the effect of rotation in the usual Sagnac effect can be analyzed. The question is shown to be related to the so-called rotating disc problem known as the Ehrenfest paradox. The relativistic formula for the Sagnac phase-shift seems (...) to depend on the way the paradox is resolved. Kinematic resolution of the Ehrenfest paradox proposed by some authors predicts the usually quoted formula for the Sagnac delay but the resolution itself is shown to be based upon some implicit assumptions regarding the behaviour of solid bodies under acceleration. In order to have a greater insight into the problem, a second version of the thought experiment involving linear motion of a “special type” of a non-rigid frame of reference is discussed. It is shown by analogy that the usually quoted special relativistic formula for the Sagnac delay follows, provided the material of the disc matches the “special type.”. (shrink)

Interleukin‐1 receptor‐associated kinase‐1 (IRAK1) is linked to the pathogenesis of atherosclerosis; however, its role in macrophage foam cell formation is not known. Therefore, the present study investigated the role of IRAK1 in lipid uptake, biosynthesis, and efflux in THP‐1 derived macrophages and human monocyte‐derived macrophages (HMDMs). Ox‐LDL (40 μg/mL, 15 minutes–48 hours) treatment induced time‐dependent increase in IRAK1, IRAK4, and Stat1 activation in THP‐1 derived macrophages. IRAK1/4 inhibitor (INH) or IRAK1 siRNA significantly attenuated cholesterol accumulation, DiI‐Ox‐LDL binding, and uptake while (...) cholesterol efflux to apoAI and HDL was enhanced in THP‐1 derived macrophages and HMDMs. Ox‐LDL treatment significantly increased the mRNA expression of CD36, LOX‐1, SR‐A, ABCA1, ABCG1, Caveolin‐1, CYP27A1 while that of SR‐BI was decreased. IRAK1/4 inhibition or IRAK1 knockdown, however, attenuated Ox‐LDL‐induced CD36 expression; augmented ABCA1 and ABCG1 expression while expression of others was unaffected in THP‐1 derived macrophages and HMDMs. Moreover, IRAK1/4 inhibition had no significant effect on genes involved in lipid biosynthesis. In IRAK1/4 INH pre‐treated THP‐1 derived macrophages Ox‐LDL‐induced Stat1 phosphorylation and its binding to CD36 promoter was significantly attenuated while LXRα expression and its binding to the ABCA1/ABCG1 locus, NFATc2 activation and its binding to ABCA1 locus was enhanced. The present study thus demonstrates that IRAK regulates lipid accumulation by modulating CD36‐mediated uptake and ABCA1‐, ABCG1‐dependent cholesterol efflux. Therefore, IRAK1 can be a potential target for preventing macrophage foam cell formation. (shrink)

The evaluation of tourism competitiveness is an important tool for analyzing the potential of tourism in a specific context. Enshi Autonomous Prefecture in China is selected as a case through which to explore the potential of mountain tourism and its competitiveness in the tourism industry. This study develops EAP’s mountain tourism competitiveness model focusing on three criteria: core competitiveness of mountain tourism, the economic environment’s competitiveness, and infrastructure competitiveness. Context-specific customized evaluation index has been applied to data collected from EAP (...) Statistical Yearbook for 2005–2014. The study reveals that the value of EAP’s mountain tourism core competitiveness, economic and environmental competitiveness, and infrastructure competitiveness are 84.292, 13.4, and 2.308%, respectively. When tourism core competitiveness is increased by one unit, EAP’s mountain tourism competitiveness will increase by 0.84292 units. Similarly, when economic environment competitiveness is increased by one unit, EAP’s mountain tourism competitiveness will increase by 0.134 units. EAP’s mountain tourism competitiveness increases by 0.02308 units when infrastructure competitiveness increases by one unit. The major reasons for low levels of competitiveness were lack of awareness of the county authority, a low level of cooperation, and weak infrastructure. The recommendations from the study’s findings are as follows. Firstly, the county authority should appropriately improve the relationship between competition and cooperation, maintaining cooperation in competition, and competition in cooperation. Secondly, the county authority should strengthen communication by establishing an effective coordinated mechanism. Thirdly, the county authority should improve the sense of cooperation and jointly develop the mountain tourism market. Fourthly, the county authority should improve the construction of tourism infrastructure and break down the barriers to tourism cooperation. The study’s findings help develop a “win-win” cooperation mechanism within the competition and support the sustainable development of the mountain tourism industry while reducing poverty and promoting the revitalization of the mountains of China. (shrink)

Synergetic governance is a practical approach to ensure quality in the teaching-learning process at multi-dimensional perspectives. This study intends to explore the potential of a synergetic governance approach in the vocational education system. A systematic literature review has been done by applying the PRISMA approach. The last 21 years' literature has been analyzed, and a synergetic governance model has been developed. This study reveals that the synergetic governance of education deals with integrating all available resources to enhance development by meeting (...) the demands of market, society, and nation as a new paradigm. An effective vocational education system requires the participation of all related stakeholders in the governance system. This study has developed an “intervention-approach-synergy-integration” mechanism to show how the education elements are connected to each other. The study reveals that the major synergetic elements are openness, equilibrium, dynamism and cooperation. To ensure synergetic governance, these elements should be integrated with an educational institution, market, public, society, state and private organization. It argues that the synergetic governance of these related components can reduce the demand and supply gap of quality vocational graduates in the industry – academy sectors. This study recommends incorporating multi-subjects' synergetic governance to expedite the marketable quality of vocational education. (shrink)

Nowadays, mobile telephony interruptions in our daily life activities are common because of the inappropriate ringing notifications of incoming phone calls in different contexts. Such interruptions may impact on the work attention not only for the mobile phone owners, but also for the surrounding people. Decision tree is the most popular machine-learning classification technique that is used in existing context-aware mobile intelligent interruption management model to overcome such issues. However, a single-decision tree-based context-aware model may cause over-fitting problem and thus (...) decrease the prediction accuracy of the inferred model. Therefore, in this paper, we propose an ensemble machine-learning-based context-aware mobile telephony model for the purpose of intelligent interruption management by taking into account multi-dimensional contexts and name it “E-MIIM”. The experimental results on individuals’ real-life mobile telephony data sets show that our E-MIIM model is more effective and outperforms existing MIIM model for predicting and managing individual’s mobile telephony interruptions based on their relevant contextual information. (shrink)

This paper is an attempt to discuss how ethics associated with social research in connection with the collection of authentic and reliable data, use of appropriate data process and impartial data analysis for preparing an acceptable research report. Ethics is closely related to moral integrity, and values associated with appropriate methods and techniques applied for collection of reliable and authentic information that ensure the trust worthy research findings. This paper is based on secondary data collected through reviewing the relevant literatures. (...) This paper examine to what extent the research findings contribute to the knowledge of planners and policy makers in formulating the appropriate policy and at the same time preparing effective as well as pragmatic planning based on the quality of research findings and finally thus may affect on development. (shrink)

In his book, The Logic of Democracy, T.L. Thor son has published a chapter entitled "Majority Rule and Minority Rights". In this paper he has pointed out a controversy which has arisen between "natural rights democrats" and "majority rule democrats." In this paper I argue that elected representatives represent the majority and their rule can be called the rule of the majority so long they can protect the rights of individuals. This is why the natural rights of man are more (...) fundamental and essential than majority rule. In conclusion, I insist that neither "natural rights" nor "majority rule" can be called the elements of democracy. If the former and the latter could have been understood as the end of democracy and the means to achieve the end, respectively, then the controversy would not have arisen. (shrink)

In his book, The Logic of Democracy, T.L. Thor son has published a chapter entitled "Majority Rule and Minority Rights". In this paper he has pointed out a controversy which has arisen between "natural rights democrats" and "majority rule democrats." In this paper I argue that elected representatives represent the majority and their rule can be called the rule of the majority so long they can protect the rights of individuals. This is why the natural rights of man are more (...) fundamental and essential than majority rule. In conclusion, I insist that neither "natural rights" nor "majority rule" can be called the elements of democracy. If the former and the latter could have been understood as the end of democracy and the means to achieve the end, respectively, then the controversy would not have arisen. (shrink)

In their book entitled “Democracy and the American Party System” Austin Ranney and (Willmoore Kendall have brought a charge again the pluralists that they denied the desirability of creating sovereign state and as such, according to them, they were opponents of democracy as well as of the very idea of government. The aim of this paper is to refute their charge and thereby to establish the view that the pluralists are in fact strong supporters of democracy in the real sense (...) of the term and of popular sovereignty. What did most of them was that they made an attempt to bring to light the fact that democracy, as it is being practiced almost everywhere in the world, ultimately leads to denial of popular sovereignty, the basic element of self-government. Self-government can best be realized where the people is the real sovereign neither the state nor the numerical majority. And the government formed by the representatives elected in a traditional party-based election does not therefore, mean self-government. It can at best be called the government of the majority. Majority rule does not anyway mean democracy. It may be called ‘numbersocracy’ after the proper terminology of Ranney and Kendall. Democracy, de facto, is nothing other than majority rule that is best termed by John Calhoun, the ex-vice-president of the U.S.A, as the ‘rule by numerical majority’. ‘Numerical’ majority”, says he, “is not the people”. I strongly adhere to the pluralists’ view and therefore, conclude with an insistent assertion that numerical majority rule in disguise of democracy has in fact ruled out popular sovereignty. (shrink)

In their book entitled “Democracy and the American Party System” Austin Ranney and (Willmoore Kendall have brought a charge again the pluralists that they denied the desirability of creating sovereign state and as such, according to them, they were opponents of democracy as well as of the very idea of government. The aim of this paper is to refute their charge and thereby to establish the view that the pluralists are in fact strong supporters of democracy in the real sense (...) of the term and of popular sovereignty. What did most of them was that they made an attempt to bring to light the fact that democracy, as it is being practiced almost everywhere in the world, ultimately leads to denial of popular sovereignty, the basic element of self-government. Self-government can best be realized where the people is the real sovereign neither the state nor the numerical majority. And the government formed by the representatives elected in a traditional party-based election does not therefore, mean self-government. It can at best be called the government of the majority. Majority rule does not anyway mean democracy. It may be called ‘numbersocracy’ after the proper terminology of Ranney and Kendall. Democracy, de facto, is nothing other than majority rule that is best termed by John Calhoun, the ex-vice-president of the U.S.A, as the ‘rule by numerical majority’. ‘Numerical’ majority”, says he, “is not the people”. I strongly adhere to the pluralists’ view and therefore, conclude with an insistent assertion that numerical majority rule in disguise of democracy has in fact ruled out popular sovereignty. (shrink)

‘Yata mat tata path’ means ‘every faith is a path to God’. It is such a generous religious doctrine that has admitted the truth of all religions. This doctrine emerges on the soil of India in the second half of the Nineteenth Century as a reaction against the notion that my religion is the only true religion and other religions are false. According to Sri Ramkrishna, the exponent of the dictum, such dogmatic assertions promote contemptuous attitude towards the followers of (...) other religions,which gives birth to violent strife and bloodshed on earth. All these can generally be considered as the side effects of religions. The aim of this paper is to interpret the importance of the doctrine, yata mat tata path as the antidote of the side effects of religions. The interpretation at the end explicitly exposes itself as an ecological approach to religions. By admitting the truth and spiritual achievements of all religions in spite of their ritualistic diversity, the doctrine yata mat tata path advocates for religious harmony and thus approximates ecology, which discovers interdependent co-existence of and unity in diversified biotic communities. (shrink)

Coronary arteries were studied on 110 postmortem human hearts during January 2000 to December 2001 in the department of Anatomy and Microbiology, Bangladesh Medical College to observed. The pattern of coronary dominance and its relation with atherosclerosis was observed. Atherosclerosis was found in 49(44.5%) samples, among which 37(56.%) were from male and 12(26.7%) from female hearts. This difference was significant (P<0.01). Right dominance was observed in 72 (65.5%) cases while 17 (15.5%) had left dominance and 21 (19.1%) had balanced type (...) of circulation. Balanced type of circulation was observed more among females (14; 66.7%) while left dominance was more frequent among males (13; 76.5 %). This deference on the basis of sex was significant (P<0.05). Significant (P<0.001) relationship was also observed between atherosclerosis and dominance of coronary artery. It may be concluded that atherosclerosis was present in almost half of the studied subjects and was found more among males. Left dominance was more frequently present among males it was associated with atherosclerosis. (shrink)

The design and development of appropriate regulatory mechanisms have attracted renewed attention in recent years. In particular, a shift towards voluntary self-regulatory mechanisms has been witnessed within many industries, such as the Australian mining and petroleum industries which have developed voluntary codes of conduct. This paper analyses the development of different regulatory forms and provides a brief comparative analysis of the two main voluntary codes of conduct used by the Australian mining and petroleum industries. In particular, the study focuses on (...) the integration of social sustainability elements within these frameworks that help contribute to solving issues such as coverage of human rights, approaches to employee and community relations, systems of stakeholder engagement, community consultation and public reporting. The study concludes that stakeholders have an important role to play in driving the introduction of voluntary regulation. This phenomenon can be traced back to how a company’s need to maintain its legitimacy, or social licence to operate, often motivates it to go beyond compliance. By providing a fuller understanding of factors driving the evolution of different regulatory mechanisms, this study has important implications for policy makers and practitioners interested in developing effective regulation. (shrink)

Neuromarketing relies on Brain Computer Interface (BCI) technology to gain insight into how customers react to marketing stimuli. Marketers spend about$750 billion annually on traditional marketing camping. They use traditional marketing research procedures such as Personal Depth Interviews, Surveys, Focused Group Discussions, and so on, which are frequently criticized for failing to extract true consumer preferences. On the other hand, Neuromarketing promises to overcome such constraints. This work proposes a machine learning framework for predicting consumers' purchase intention (PI) and affective (...) attitude (AA) from analyzing EEG signals. In this work, EEG signals are collected from 20 healthy participants while administering three advertising stimuli settings: product, endorsement, and promotion. After preprocessing, features are extracted in three domains (time, frequency, and time-frequency). Then, after selecting features using wrapper-based methods Recursive Feature Elimination, Support Vector Machine is used for categorizing positive and negative (AA and PI). The experimental results show that proposed framework achieves an accuracy of 84 and 87.00% for PI and AA ensuring the simulation of real-life results. In addition, AA and PI signals show N200 and N400 components when people tend to take decision after visualizing static advertisement. Moreover, negative AA signals shows more dispersion than positive AA signals. Furthermore, this work paves the way for implementing such a neuromarketing framework using consumer-grade EEG devices in a real-life setting. Therefore, it is evident that BCI-based neuromarketing technology can help brands and businesses effectively predict future consumer preferences. Hence, EEG-based neuromarketing technologies can assist brands and enterprizes in accurately forecasting future consumer preferences. (shrink)

This paper aims to introduce a robust framework for forecasting demand, including data preprocessing, data transformation and standardization, feature selection, cross-validation, and regression ensemble framework. Bagging ), boosting and extreme gradient boosting regression ), and stacking are employed as ensemble models. Different machine learning approaches, including support vector regression, extreme learning machine, and multilayer perceptron neural network, are adopted as reference models. In order to maximize the determination coefficient value and reduce the root mean square error, hyperparameters are set using (...) the grid search method. Using a steel industry dataset, all tests are carried out under identical experimental conditions. In this context, STACK1 and STACK2 models provided better performance than other models. The highest accuracies of R2 of 0.97 and 0.97 are obtained using STACK1 and STACK2, respectively. Moreover, the rank according to performances is STACK1, STACK2, XGBR, GBR, RFR, MLP, ELM, and SVR. As it improves the performance of models and reduces the risk of decision-making, the ensemble method can be used to forecast the demand in a steel industry one month ahead. (shrink)

FAO has a unique and essential rolein addressing the ethical problems facinghumanity and in making these problems intoopportunities for practical resolution. A broadrange of ethical issues in agriculture,fisheries, and forestry were identified byanalysis of the literature and by interviewswith FAO staff. Issues include sharing accessto and preserving natural resources,introduction of new technology, conservatismover the use of genetic engineering, ethics inanimal agriculture, access to information, foodsecurity, sustainable rural development,ensuring participation of all people indecision making and in receiving benefits ofagriculture, reducing corruption, (...) andinvolvement of private and public sectors indecision making. Rather than viewing theseissues as problems, they should be viewed asopportunities for debate, learning aboutothers' views, and resolution. The UnitedNations has an important role to play in howdecisions are made in the global ethical debatein food and agriculture. The ethical role ofFAO is to promote global food security,balanced conservation, management andutilization of natural resources, andsustainable rural development. FAO should fullyand publicly assume its ethicalresponsibilities, gathering and sharinginformation on ethics in its areas of mandate,acting as an interactive forum, and providingexpert guidance on policy options and choicesbased on practical ethical analysis. (shrink)