Background: Increasing resistance of Pseudomonas aeruginosa to ciprofloxacin in ICU/burn units has created a problem in the treatment of infections caused by this microorganism. -/- Methods: Fifty P. aeruginosa strains were isolated from burn patients hospitalized in the Kerman Hospital during May 1999-April 2000 and were tested for in-vitro sensitivity to different antibiotics by disc diffusion breakpoint assay. The isolates were subjected to minimum inhibitory concentration (MIC) test by agar dilution method. Existence of the plasmids was also investigated in the (...) isolates. -/- Results: Thirty-four patients infected with ciprofloxacin strains showed MIC of 8 mg/ml [p<0.001]. Sixteen patients were infected with sensitive strains exhibiting MIC range of 0.0125-0.125 ± 0.033 mg/ml. The isolates were also also resistant to other antibiotics [p<0.001]. Plasmid isolation and agarose gel electrophoresis (0.7%) revealed three plasmid bands in strains 8 and 16, and one band in strain 35. -/- Conclusion: The emergence of ciprofloxacin resistance of P. aeruginosa in burn patients is alarming since this antibiotic has only recently been introduced onto the market in Iran. One important observation was that some isolates exhibited cross resistance to other antibiotics. Furthermore, some strains were carriers of plasmids which might have acted as the potential source of acquired resistance in the hospital setting. -/- . (shrink)

Definitions of consciousness need to be sufficiently broad to include all examples of conscious states and sufficiently narrow to exclude entities, events and processes that are not conscious. Unfortunately, deviations from these simple principles are common in modern consciousness studies, with consequent confusion and internal division in the field. The present paper gives example of ways in which definitions of consciousness can be either too broad or too narrow. It also discusses some of the main ways in which pre-existing theoretical (...) commitments (about the nature of consciousness, mind and world) have intruded into definitions. Similar problems can arise in the way a “conscious process” is defined, potentially obscuring the way that conscious phenomenology actually relates to its neural correlates and antecedent causes in the brain, body and external world. Once a definition of “consciousness” is firmly grounded in its phenomenology, investigations of its ontology and its relationships to entities, events and processes that are not conscious can begin, and this may in time transmute the meaning (or sense) of the term. As our scientific understanding of these relationships deepen, our understanding of what consciousness is will also deepen. A similar transmutation of meaning (with growth of knowledge) occurs with basic terms in physics such as "energy", and "time.". (shrink)

Der Einsatz empirischer Forschungsmethoden in der Medizinethik hat zu Forderungen nach einem gewandelten Selbstverständnis der Medizinethik geführt, die sich mehr als eine integrierte Disziplin aus Sozialwissenschaften und Ethik verstehen solle. Dagegen wird hier die These vertreten, dass über Sinn und Unsinn des Einsatzes empirischer Methoden zunächst eine moralphilosophische Diskussion erforderlich ist. Medizinethiker müssen ausweisen können, welche empirischen Forschungsresultate zur Beantwortung normativer Fragen erforderlich sind. Ein solcher Ausweis beruht seinerseits jedoch auf normativen Annahmen, die ihrerseits moralphilosophischer Legitimation bedürfen. Der Beitrag untersucht (...) daher den Einsatz empirischer Methoden in der Medizinethik im Hinblick auf Verhältnis von ethischem Grundlagendiskurs und Methodologie der angewandten Ethik. Abschließend wird gefragt, ob nicht ein Großteil von empirischen Studien in der Medizinethik aus forschungsethischen Gründen problematisch ist. (shrink)

Zusammenfassung: Fehlinterpretierte Dokumente und ignorierte physikalische Fakten: Die Geschichte von,Hitlers Atombombe‘ muss korrigiert werden. Warum haben die deutschen Physiker während des Zweiten Weltkriegs keine Atombombe entwickelt? Seit mehr als 25 Jahren sind sich die Historiker einig, dass die deutschen Physiker wussten, wie eine Atombombe gebaut werden muss, dass aber ein Programm wie das amerikanische Manhattan‐Projekt zu ihrer Realisierung in Deutschland, erst recht während des Krieges, unmöglich war. Eine genaue Analyse aller erhaltenen Original‐Dokumente über die Arbeit an der Atombombe während des,Dritten (...) Reichs‘ zeigt jedoch erhebliche Fehler der Autoren durch unvollständige Analyse der Dokumente, falsches Verständnis naturwissenschaftlicher Erläuterungen und Ignorieren physikalischer Fakten. Es wird nachgewiesen, dass die deutschen Physiker bis zum Ende des Krieges nicht bemerkt hatten, dass eine Atombombe nur mit schnellen Neutronen realisiert werden kann. Nur Heisenberg hatte das richtige Prinzip spät erkannt, es aber nicht eindeutig kommuniziert und auch in keiner Weise physikalisch vertieft. Die physikalisch korrekte Interpretation der Dokumente zeigt, dass die deutschen Physiker während des Krieges erfolglos versuchten, einen Reaktor zu entwickeln, der auch eine Voraussetzung für den Bau einer Plutonium‐Bombe gewesen wäre. Aber sie wussten nicht, wie eine Bombe realisiert werden kann, weil sie nie an einer realistischen Theorie der Atombombe gearbeitet hatten. Summary: Misinterpreted Documents and Ignored Physical Facts: The History of ‘Hitler's Atomic Bomb’ needs to be corrected. Why have the German physicists not developed an atomic bomb during World War II? For more than 25 years, the historians agree that they knew how to build the bomb, but that a bomb‐development programme of the size of the US‐Manhattan‐Project would not have been possible in wartime Germany. A detailed analysis of all preserved documents on the German atomic bomb research during the ‘Third Reich’, however, reveals considerable mistakes by the authors due to incomplete analysis of documents, misinterpretations of scientific explanations and ignoring of physical facts. It is shown that until the end of the war the German physicists did not know that an atomic bomb can only be made with fast neutrons, except Heisenberg, who, however, discovered it rather late, did not communicate it clearly and did not study any bomb physics. The physically correct interpretation of the documents reveals that the German physicists worked unsuccessfully on a reactor, which would have been a prerequisite for a plutonium bomb. But they did not know how to build a bomb because they never worked on a realistic bomb theory. (shrink)

O texto procura refletir sobre o diálogo contemporâneo da Teologia com a Arte a partir da antropologia contida em ambas que permite re-significar: 1) o aspecto soteriológico da fé, como aquela que vem salvar o humano gerando comunhão e não condená-lo, gerando marginalização; 2) refazer os fundamentos da razão como razão fria para uma razão voltada para seu compromisso com a vida.

In this paper we want to reconcile two apparently conflicting intuitions: the first is that what a speaker means is just a function of his or her communicative intentions, independently of what the hearer understands, and even of the actual existence of a hearer; the second is that when communication is carried out successfully, the resulting meaning is, in some important sense, jointly construed by the speaker and the hearer. Our strategy is to distinguish between speaker’s meaning, understood as a (...) personal communicative intention, and joint meaning, understood as a joint construal of the speaker and the hearer. We define joint meaning as a type of propositional joint commitment, more precisely as the joint commitment of a speaker and a hearer to the extent that a specific communicative act has been performed by the speaker. Joint meaning is therefore regarded as a deontic concept, which entails obligations, rights, and entitlements, and cannot be reduced to epistemic and volitional mental states like personal belief, common belief, personal intention, and communicative intention. (shrink)

To say that the liturgy is a question of faith means that your object is transcendent and has to do with God and with one unique feature, ie, the very act of celebrating an act of faith. The liturgy is not only motivated by faith, but it is their faith in words, which is a very peculiar dimension.

This review summarises why it is difficult for Darwinian evolutionary theory to explain the existence and function of consciousness. It then evaluates whether Humphrey's book Soul Dust overcomes these problems. According to Humphrey, consciousness is an illusion constructed by the brain to enhance reproductive fitness by motivating creatures that have it to stay alive. Although the review entirely accepts that consciousness gives a first-person meaning to existence, it concludes that Humphrey does not give a convincing account of how this can (...) arise from random variations in the genome. Nor does he demonstrate how first-person experiences might enter into or be reducable to third-person functioning. The review concludes that Humphrey's case is unconvincing, and goes on to suggest that an entirely different, non-reductive approach may be required to understand consciousness. (shrink)

O texto procura refletir, de maneira prospectiva, sobre a contribuição que a Conferência de Aparecida poderá dar à igreja universal, e em especial para o continente latino-americano. Diagnostica linhas de continuidade com a prática atual da igreja e enumera esperanças das comunidades eclesiais com relação à V Conferência.

Ethical conflicts have always been connected with new techniques of reproductive medicine such as in-vitro fertilization. The fundamental question is: When does human life begin and from which stage of development should the embryo be protected? This question cannot be solved by scientific findings only. In prenatal ontogenesis there is no moment during the development from the fertilized oocyte to a human being which could be recognized as an orientation point for all ethical problems connected with the question of the (...) right to dispose of prenatal life (interruption of pregnancy, research on embryos). The protection of an individual human life must be valid for all in the same manner and from the very beginning on. It must not depend on value judgments or on stages of development, so-called grades of humanity, because these would then become selection criteria. Procreated life must have the right to be born. These were the essential ethical arguments which led to the German Embryo Protection Law. (shrink)

Während die terminale Sedierung neueren niederländischen Erhebungen zufolge bereits in mehr als 5% aller Sterbefälle zur Leidensminderung am Lebensende angewandt wird, sind viele der durch dieses Verfahren aufgeworfenen begrifflichen und ethischen Fragen weiterhin offen. Kontrovers ist insbesondere die begriffliche Einordnung der Kombination von terminaler Sedierung und Behandlungsabbruch sowie die Frage nach den dafür einschlägigen ethischen Kriterien. Ausgehend von einer Analyse von drei Szenarien mit unterschiedlicher kausaler Rollenverteilung argumentiere ich dafür, den Standardfall der Kombination von terminaler Sedierung und Behandlungsabbruch unter die (...) Kategorie der „passiven Sterbehilfe“ zu subsumieren und für sie dieselben ethischen Kriterien wie für den Behandlungsabbruch allein gelten zu lassen. Eine tentative vergleichende Bewertung ergibt, dass die terminale Sedierung als ultima ratio der Leidensminderung am Lebensende gegenüber der Alternative des assistierten Suizids insgesamt als ethisch vorzugswürdig gelten sollte, ohne jedoch die Alternative des assistierten Suizids als in toto unzulässig erscheinen zu lassen. (shrink)

O Concílio Vaticano II foi um dos eventos mais importantes da história da Igreja do século XX. Partindo de sua história e dos documentos aprovados pelos bispos conciliares, o pós-concílio caracteriza-se, nesses seus 40 anos, por um debate acalorado e por luta identitária sobre como ele deve ser recepcionado pela Igreja universal e pelas igrejas particulares. Dessa forma, o presente artigo tem como objetivo apresentar as principais linhas hermenêuticas do Vaticano II, apontando alguns autores e obras sobre a discussão.

O artigo apresenta uma analise a partir da renovação eclesiológica do Vaticano II, em seguida apresenta a pneumatologia como origem desta renovação. A comunhão na Igreja só será possível através do Espírito Santo.

Neste artigo interessa-nos abordar alguns aspectos sobre a relação entre a Sagrada Escritura e a Liturgia, de modo particular aqueles elementos concernentes à reorganização e confecção levadas a cabo pela reforma litúrgica do concílio Vaticano II do livro litúrgico que contém as perícopes bíblicas lidas na liturgia da Palavra durante as celebrações eucarísticas, isto é, o Lecionário da Missa. Para esta abordagem, nos servirá, em grande medida, o relato sobre os trabalhos da Reforma Litúrgica - relato este ainda inédito no (...) Brasil - escrito por D. Annibale Bugnini, Secretário do Consilium, a comissão encarregada para a aplicação dos princípios de reforma estipulados pela Constituição Sacrosanctum Concilium. (shrink)

Das belgische Parlament verabschiedete am 28. Mai 2002 das Euthanasiegesetz. Hierdurch wurden die verschiedenen Pflegeeinrichtungen mit einem neuen rechtlichen Rahmen konfrontiert. Das neue Gesetz lässt Euthanasie unter bestimmten Voraussetzungen zu. Dieser Beitrag möchte einige Orientierungspunkte für einen vertretbaren Umgang mit dem Euthanasiegesetz in katholischen Pflegeeinrichtungen liefern. Als Ausgangspunkt hierfür gilt der Grundsatz, dass alles Mögliche getan werden muss, um dem Sterbenden und seiner Umgebung den nötigen Beistand und die bestmögliche Betreuung zu geben und seinem Verlangen nach einem menschenwürdigen Lebensende entgegenzukommen. (...) Wird um Euthanasie gebeten, so entscheiden sich die katholischen Pflegeeinrichtungen Belgiens für die palliative Filterprozedur. Bevor hier die Konturen einer solchen Sorge für ein menschenwürdiges Lebensende umrissen werden, werden zunächst einige fundamentale Annahmen zum Menschsein und dem Wert der Autonomie inhaltlich beleuchtet. Der Autor stützt sich hierfür auf eine relationale Auffassung der Person, wie diese innerhalb der personalistischen Strömungen der Ethik entwickelt wird. (shrink)

The story of Ted Honderich, philosopher, a story of a perilous philosophical life, marked by critical examination, and a compelling personal life full of human drama. This is the story of Ted Honderich's perilous progress from boyhood in Canada to the Grote Professorship of Mind and Logic at University College London, A. J. Ayer's chair. It is compelling, candid and revealing about the beginning and the goal, and everything in between: early work as a journalist on The Toronto Star, travels (...) with Elvis Presley, arrival in Britain, loves and friendships, academic rivalries and battles, marriages and affairs, self-interest and empathy. It sets out resolutely to explain how and why it all happened. It is as much a narrative of Ted Honderich's philosophy. He makes hard problems real. Philosophy from consciousness and determinism to political violence and democracy comes into sharp focus. Along the way, questions keep coming up. Does the free marriage owe anything to the analytic philosophy? What are the costs of truth? Are the politics of England slowly making it an ever-better place? Is an action's rightness independent of the mixture of motives out of which it came? (shrink)

Following an examination of the missions of industry and the university there is a comparison of the ‘wish-lists’ of industry and the university. These ‘wish-lists’ have both similarities and differences. Some of the differences are expressed in a further section on the kinds of interactions that neither institution wants from the other. In the canonical university, the culture values features such as openness, individuality and the de-emphasis of monetary matters, whereas in the archetypal industry the prevailing ethos tends towards secrecy, (...) teamwork and financial advancement. When two such cultures are juxtaposed under conditions where the survival of the university is dependent, in part, on receiving funds from industry, there is a danger of an erosion of academic standards as the university becomes more oriented to service the needs of industry as opposed to the development of its students and its independent scholastic and research activities. Industry, however, is in a position to derive benefit from the interaction without incurring an equivalent cost. These issues are discussed and some recommendations are made to improve the ethical nature of the interaction. (shrink)

Versuche zur Geschlechtswahl bei der Befruchtung führten in jüngerer Zeit zu anwendbaren, wenngleich noch eingeschränkt erfolgssicheren Techniken. Deren ethische und rechtliche Bewertungen stehen im Mittelpunkt dieser Abhandlung. In Gesellschaften und Kulturen mit traditioneller Bevorzugung männlicher Nachkommenschaft gibt es einerseits ein starkes Interesse für die Geschlechtswahl, andererseits wird in einigen westlichen Ländern der vorgeburtlichen Geschlechtswahl sehr geringe praktische Bedeutung beigemessen. Dabei unterscheidet sich die Verfügbarkeit der entsprechenden reproduktionsmedizinischen Verfahren von freier Zugänglichkeit zu allen Methoden (Präimplantationsdiagnostik, Spermatozoentrennung usw.) des Fortpflanzungsmedizinmarkts (USA) bis (...) hin zu strenger Reglementierung (Deutschland). Es wird anhand der wissenschaftlichen Literatur der Frage nachgegangen, welche für die Begründung rechtlicher Regelung beachtlichen sozialen oder gesundheitlichen Gefährdungen durch präkonzeptionelle Geschlechtswahl verursacht werden könnten, und welche Gründe es andererseits für die Zulässigkeit sozial motivierter präkonzeptioneller Geschlechtswahl gibt. (shrink)

Eine patientengerechte Versorgung ist ein hohes Ziel. Unangemessene Behandlung wie Unter- oder Überversorgung zu erkennen und zu vermeiden, stellt Ärztinnen/Ärzte und Pflegende am Krankenbett vor schwierige Entscheidungen. Hier ist die Entwicklung von praxistauglichen Orientierungshilfen angezeigt, die wissenschaftlichen Kriterien genügen und nicht allein auf Konsens beruhen. Die vorliegende Arbeit versucht, zentrale Normen zur Vermeidung von Über- und Unterversorgung zu formulieren und theoretisch zu fundieren. Dafür wird auf Basis einer Interessen-basierten Ethik eine Graduierung der Autonomie vorgenommen, indem zwischen schwacher und starker Autonomie (...) unterschieden wird. (shrink)

Der Einsatz von Psychopharmaka im Altenpflegeheim unterliegt aufgrund institutioneller und struktureller Besonderheiten dieses Versorgungsbereiches, aber auch aufgrund der großen Abhängigkeit und Vulnerabilität eines großen Teils der Altenpflegeheimbewohner in besonderer Weise der Gefahr, in inadäquater und missbräuchlicher Weise durchgeführt zu werden. Die Beachtung der ethischen Grundprinzipien des Wohltuns und des Nichtschadendürfens sowie des Respekts vor der Autonomie der Bewohner (bzw. der Patienten) sollte für alle an der Versorgung unmittelbar und mittelbar Beteiligten handlungsleitend sein. Zum Schutz der Heimbewohner, aber auch mit dem (...) Ziel die Versorgungsqualität in diesem Bereich nachprüfbar zu verbessern, werden in diesem Beitrag Kriterien zur Definition einer inadäquaten bzw. adäquaten Anwendung von Psychopharmaka explizit formuliert, sowie deren Implementierung in prozessorientierte Handlungsalgorithmen und Behandlungsleitlinien vorgeschlagen. Darüber hinaus sollen die Möglichkeiten und Grenzen nicht-pharmakologischer, psychologischer Interventionen als Alternative zur Psychopharmakamedikation diskutiert und hinsichtlich ihrer ethischen Implikationen reflektiert werden. (shrink)

This fourth volume traces the history of Renaissance philosophy and seventeenth century rationalism, covering Descartes and the birth of modern philosophy.

The end of Conciliarism was the Pope's return to Rome and the strengthening of the papacy in the West. The decline of the Roman Empire in the East with the fall of Constantinople in 1453 puts an end to the Medieval period and the emergence of the modern period of history and also of the Church. In the modern period of history began the European overseas expansionism and disintegrate the Church in Europe. The advent of the French revolution in 1789 (...) scored the beginning of Contemporary and Period marked definitely the Church as a prophetic sign living and proclaiming the joys and hopes in Christ Jesus to people with greater intensity. (shrink)

A pesquisa procura não só conceituar e expor a estética de Hegel, mas também elucidar seu pensamento referente à questão. Em suas palavras, estética seria o belo artístico, criado pelo homem. Nesse sentido, a ascendência da arte está na precisão que o homem tem de objetivar seu espírito, morfosiando o mundo e também se transformando. Assim, nas páginas que se seguem há uma exposição do conceito vulgar de estética em contraponto a visão hegeliana, para tanto, o filósofo cita a ascensão (...) e declínio do conceito de arte e estética buscando contextualizá-la enquanto função na história do homem. (shrink)

O grupo de escritos chamados Cartas Católicas, junto à chamada Carta aos Hebreus apresenta-se como um testemunho extra-paulino do Cristianismo primitivo. De fato, é o conjunto dos textos narrativos (Evangelhos e Atos) e do Corpus Paulinum (conjunto dos escritos atribuídos a Paulo) que são mais marcantes na compreensão do Evento Jesus Cristo e sua vivência e compreensão no primeiro século. Com frequência, se esquece que o Cristianismo é um fenômeno histórico e social plural. Uma pequena introdução a este tempo histórico (...) e à sua temática é sempre oportuna para compreender as raízes da Igreja. (shrink)

The purpose of this article is to demonstrate the limitation that the Latin language represents in the Code of Canon Law. In fact, the opinion advocated in the present text is that a modern tongue, like English, an international means of communication, could be more proper for the Code, since, nowadays few persons know Latin, even among the experts, and the Code is addressed to the entire people of God (lay and clergy), being the juridical instrument to put into practice (...) the Vatican II. (shrink)