Dietary changes can alter the human microbiome with potential detrimental consequences for health. Given that environment, health, and evolution are interconnected, we ask: Could diet‐driven microbiome perturbations have consequences that extend beyond their immediate impact on human health? We address this question in the context of the urgent health challenges posed by global climate change. Drawing on recent studies, we propose that not only can diet‐driven microbiome changes lead to dysbiosis, they can also shape life‐history traits and fuel human evolution. (...) We posit that dietary shifts prompt mismatched microbiome‐host genetics configurations that modulate human longevity and reproductive success. These mismatches can also induce a heritable intra‐holobiont stress response, which encourages the holobiont to re‐establish equilibrium within the changed nutritional environment. Thus, while mismatches between climate change‐related genetic and epigenetic configurations within the holobiont increase the risk and severity of diseases, they may also affect life‐history traits and facilitate adaptive responses. These propositions form a framework that can help systematize and address climate‐related dietary challenges for policy and health interventions. (shrink)

This paper presents the contributions of the French Dominican priest Louis-Joseph Lebret to the emergence of development ethics. Starting from his life and experiences, it outlines his concept of d...

In addition to their function in transport of water, ions, small metabolites, and growth factors in normal plant tissue, the plasmodesmata presumably serve as routes for cell‐to‐cell movement of plant viruses in infected tissue. Virus cell‐to‐cell spread through plasmodesmata is an active process mediated by specialized virus encoded movement proteins; however, the mechanism by which these proteins operate is not clear. We incorporate recent information on the biochemical properties of plant virus movement proteins and their interaction with plasmodesmata in a (...) model for transport of nucleic acids through plasmodesmatal channels. We propose that only single stranded (ss) nucleic acids can be transported efficiently through plasmodesmata, and that movement proteins function as molecular chaperones for ss nucleic acids to form unfolded movement protein‐ss nucleic acid complexes. These complexes are targeted to plasmodesmata. Plasmodesmatal permeability is then increased following interaction with movement protein and the entire movement complex or its nucleic acid component is translocated across the plasmodesmatal channel. (shrink)

Die fünf Bände enthalten die Hauptvorträge und eingeladene Beiträge der panels des X. Internationalen Kant-Kongresses, der 2005 in Sao Paolo stattfand.

Wissenskultur im Alten Orient: Weltanschauung, Wissenschaften, Techniken, Technologien. Edited by Hans Neumann. Colloquien der Deutschen Orient-Gesellschaft, vol. 4. Wiesbaden: Harrassowitz Verlag, 2012. Pp. xi + 433, illus. €42.

We ordinarily believe that the inhabitants of the world - including ourselves - persist over time. Such an idea, however, has puzzled philosophers for centuries. How can we change and still be the same? More specifically, is there any constitutive condition of our identity over time? And if so, does this condition involve mental aspects, physical aspects, or something else? Or is rather personal identity primitive and unanalyzable, so that our persistence is nothing but a brute fact? This volume is (...) a collection of new essays from leading figures in the field analyzing the persistence of persons and the criteria of personal identity over time. It presents an extensive discussion of the most relevant views on personal identity in contemporary metaphysics and provides new treatments of the constitutive conditions of personal persistence. (shrink)

In a recent paper, Cumpa : 319–324, 2014) argues that a scientific turn in metaphysics requires the acceptance of a materialist criterion of fundamentality, according to which the most fundamental metaphysical category is the one that provides us with a reconciliation of the ordinary world and the physical universe. He concludes that the dominant category of substance cannot be the most fundamental category, for it does not satisfy this criterion of fundamentality. The most fundamental category is instead the category of (...) fact. Although convincing, the defense of factualism over substantialism offered by Cumpa takes into account the case of classical physics without considering the physical universe of quantum mechanics. My aim in this paper is to offer a completion to Cumpa’s factualist approach. To achieve my aim, I show that substances cannot provide a satisfactory account of the relationship between the ordinary world and the physical universe even in the case of quantum mechanics, whereas a factualist approach does. (shrink)

Sargonic Cuneiform Tablets in the Real Academia de la Historia: The Carl L. Lippmann Collection. By Manuel Molina. Catálogo del Gabinete de Antigüedades. Madrid: Real Academia de la Historia and Ministerio de Cultura de la República de Iraq, 2014. Pp. 317, 337 plts.

We discuss models that attempt to provide an explanation for the violation of Bell inequalities at a distance in terms of hidden influences. These models reproduce the quantum correlations in most situations, but are restricted to produce local correlations in some configurations. The argument presented in (Bancal et al. Nat Phys 8:867, 2012) applies to all of these models, which can thus be proved to allow for faster-than-light communication. In other words, the signalling character of these models cannot remain hidden.

Humanity is threatened by global risks that cross borders and national institutions in a way that has never been experienced before. Disasters, far from being purely natural phenomena, constitute the greatest danger in a context of political, social and scientific uncertainty. A new risk-based governance appears, ranging from the introduction of problematic exceptional measures and an increased vulnerability and inequality in risk exposure. This proposal aims to deepen the analysis of the relationship between law, politics and catastrophe as the focal (...) point of the evolution of risk prevention and management and its significance for the transformations of our understanding of democracy. The research proposes to engage catastrophes by conceiving them as powerful amplifiers and epiphanies of injustices, assuming that the role of the state should be inserted into a wider reading that must include the problem of unequal distribution of risks. (shrink)

Quantum physics is often perceived as a weird and abstract theory, which physicists must use in order to make correct predictions. But many recent experiments have shown that the weirdness of the theory simply mirrors the weirdness of phenomena: it is Nature itself, and not only our description of it, that behaves in an astonishing way. This book selects those, among these typical quantum phenomena, whose rigorous description requires neither the formalism, nor an important background in physics.

Quantum physics is often perceived as a weird and abstract theory, which physicists must use in order to make correct predictions. But many recent experiments have shown that the weirdness of the theory simply mirrors the weirdness of phenomena: it is Nature itself, and not only our description of it, that behaves in an astonishing way. This book selects those, among these typical quantum phenomena, whose rigorous description requires neither the formalism, nor an important background in physics.The first part of (...) the book deals with the phenomenon of single-particle interference, covering the historical questions of wave-particle duality, objective randomness and the boundary between the quantum and the classical world, but also the recent idea of quantum cryptography. The second part introduces the modern theme of entanglement, by presenting two-particle interference phenomena and discussing Bell's inequalities. A concise review of the main interpretations of quantum physics is provided. (shrink)

Human beings possess external stores in which they put all sorts of goods to use them at some later time. In this paper we investigate this typically human adaptation using agent-based simulations. We show that the use of external stores explains many aspects of human life, allowing the agents to reduce their dependence on both the environment and the current state of their body and to be more efficient in extracting the energy contained in the environment. We analyse the spatial (...) behaviour of agents with external stores located in specific positions of the environment and we find that these agents tend to develop a sedentary life. We discuss how stores can be at the origin of many human mental and social phenomena such as the acquisition of a more extended temporal perspective, specialisation in producing different types of goods, and exchange of goods. (shrink)

Human beings possess external stores in which they put all sorts of goods to use them at some later time. In this paper we investigate this typically human adaptation using agent-based simulations. We show that the use of external stores explains many aspects of human life, allowing the agents to reduce their dependence on both the environment and the current state of their body and to be more efficient in extracting the energy contained in the environment. We analyse the spatial (...) behaviour of agents with external stores located in specific positions of the environment and we find that these agents tend to develop a sedentary life. We discuss how stores can be at the origin of many human mental and social phenomena such as the acquisition of a more extended temporal perspective, specialisation in producing different types of goods, and exchange of goods. (shrink)

Human beings possess external stores in which they put all sorts of goods to use them at some later time. In this paper we investigate this typically human adaptation using agent-based simulations. We show that the use of external stores explains many aspects of human life, allowing the agents to reduce their dependence on both the environment and the current state of their body and to be more efficient in extracting the energy contained in the environment. We analyse the spatial (...) behaviour of agents with external stores located in specific positions of the environment and we find that these agents tend to develop a sedentary life. We discuss how stores can be at the origin of many human mental and social phenomena such as the acquisition of a more extended temporal perspective, specialisation in producing different types of goods, and exchange of goods. (shrink)

The paper aims at outlining some essential Neoplatonic traits in order to accomplish an ecological Metaphysics, by developing a dynamic and intensive notion of «Selfness» within three main fields of knowledge: Biology, Psychology, Cosmology. Starting from post-cybernetics systems’ theories, by deepening Bateson’s Ecology of Mind, in the end the research will restore the ancient One-Many aporia, showing its irrefutable value.

POSSIBILIDADE JURÍDICA DE INSTITUIÇÃO DE NORMAS PENAIS INCRIMINADORAS PELA VIA DOS TRATADOS INTERNACIONAIS.

My aim in this paper is to discuss the logical form of exemplification. In order to achieve this goal, I analyze three views on the logical form of exemplification, namely, Gustav Bergmann's logical realism, Wilfrid Sellars's meta-linguistic expressivism, and Javier Cumpa's logical eliminativism. I start by examining the account advanced by Bergmann in his 1960 essay "Ineffability, Ontology, and Method," according to which the logical form of exemplification is represented by the juxtaposition of logical signs in a sentence. Then I (...) consider two alternatives to Bergmann's realism, namely, Sellars's meta-linguistic expressivism, according to which exemplification is a quasi-semantical relation that is accounted for at a meta-linguistic level; and Cumpa's molecular theory of exemplification—which I will call logical eliminativism—according to which exemplification is an eliminable constituent of facts. I conclude that neither the account advanced by Sellars nor the one provided by Cumpa is preferable to Bergmann's account of the logical form of exemplification, while offering a defense of the latter. (shrink)

Multiple selves is a conventional assumption in behavioural welfare economics for modelling intrapersonal well-being. Yet an important question is which self has normative authority over others. In this paper, we advance an argument for what we call the ‘ontological approach’ to personal identity in behavioural welfare economics. According to this approach, ethical questions – such as which preference should be granted normative authority over another – can be informed by the ontological criterion of personal persistence, which aims at determining what (...) it takes for an individual to persist from one time to another. (shrink)

This contribution aims at discussing constitutional democracy in the age of populisms, by explaining how populist movements oppose liberal-democratic constitutionalism and by presenting the thesis of a so-called ‘populist constitutionalism’, as proposed by Mark Tushnet. In the first section, a general and analytic exploration of populist phenomena will be drawn, by focusing on the so-called thesis of a ‘populist’ constitutionalism. In the second part, Tushnet’s arguments for a populist constitutionalism will be presented, through the analysis of his two main contributions: (...) Taking the Constitution Away from the Courts, in which Tushnet develops his critique of legal constitutionalism and judicial review as an undemocratic power by unelected justices, and Authoritarian Constitutionalism, a recent article in which Tushnet distinguishes between ‘authoritarian’ and ‘populist’ definitions of constitutionalism. In conclusion, such arguments will be discussed, by proposing a critical response to Tushnet’s position and presenting some risks of a majoritarian and populist constitutional democracy. (shrink)

This contribution aims at discussing constitutional democracy in the age of populisms, by explaining how populist movements oppose liberal-democratic constitutionalism and by presenting the thesis of a so-called ‘populist constitutionalism’, as proposed by Mark Tushnet. In the first section, a general and analytic exploration of populist phenomena will be drawn, by focusing on the so-called thesis of a ‘populist’ constitutionalism. In the second part, Tushnet’s arguments for a populist constitutionalism will be presented, through the analysis of his two main contributions: (...) Taking the Constitution Away from the Courts, in which Tushnet develops his critique of legal constitutionalism and judicial review as an undemocratic power by unelected justices, and Authoritarian Constitutionalism, a recent article in which Tushnet distinguishes between ‘authoritarian’ and ‘populist’ definitions of constitutionalism. In conclusion, such arguments will be discussed, by proposing a critical response to Tushnet’s position and presenting some risks of a majoritarian and populist constitutional democracy. (shrink)