The celebration of the revived Olympic games in London in the summer of 1948 gave to ‘records’ an unusually prominent place in men's thoughts and in their speech and writing, and we instinctively turn back to the ancient Greek world, which witnessed the foundation of the Olympic festival and its long history of wellnigh twelve centuries, to seek traces of any similar phenomenon.

Of all the numerous inscriptions which throw light “upon the organization and activities of the ancient religious and social guilds, none is more valuable and none more vivid than that which contains the minutes of a meeting of the Athenian Iobacchi followed by acomplete text of the statutes which were then unanimously ratified. This document, originally published by S. Wide in A th. Mitt. XIX. 248 sqq., appears in a number of well-known and widely accessible collections—Dittenberger's S.I.G. 737, 1109; Roberts (...) andGardner's Introduction to Greek Epigraphy, II. No. 91; Ziehen's Leges Graecorum Sacrae, II. 46; Michel's Recueil, 1564; and I.G. II. 1368—and has been discussed in detail by E. Maass , who republishes the text with a translation and commentary, and by E. Drerup. (shrink)

Ethics consultation is a commonly applied mechanism to address clinical ethical dilemmas. However, there is little information on the viewpoints of health care providers towards the relevance of ethics committees and appropriate application of ethics consultation in clinical practice. We sought to use qualitative methodology to evaluate free-text responses to a case-based survey to identify thematically the views of health care professionals towards the role of ethics committees in resolving clinical ethical dilemmas. Using an iterative and reflexive model we identified (...) themes that health care providers support a role for ethics committees and hospitals in resolving clinical ethical dilemmas, that the role should be one of mediation, rather than prescription, but that ultimately legal exposure was dispositive compared to ethical theory. The identified theme of legal fears suggests that the mediation role of ethics committees is viewed by health care professionals primarily as a practical means to avoid more worrisome medico-legal conflict. (shrink)

Excerpt from De Finibus Bonorum Et Malorum: Libri Quinque About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We (...) do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works. (shrink)

These words occur in Appian's account of the riot which led to the death of Tiberius Sempronius Gracchus in 133 B.C. The tribunician elections had been adjourned from the previous day, and Gracchus, who irregularly sought re-election, had with his supporters taken possession of the temple of Jupiter on the Capitol. The assembly broke up in disorder amid wild rumours that Gracchus had deposed all his colleagues or had declared himself tribune for the following year without election or had actually (...) demanded the diadem. The Senate meanwhile had been in session in the temple of Fides, and upon receipt of the news from the Capitol Publius Cornelius Scipio Nasica Serapio urged the consul, Publius Mucius Scaevola, to crush the tyrant. When he declared that he would not put any citizen to death without trial, Nasica, calling loudly upon those who desired the safety of their country to follow him, mounted the Capitol at the head of a considerable body of Senators and led the attack on Gracchus and his partisans. (shrink)

We propose a conceptual model that maps the causal pathways relating biological evolution to cultural change. It builds on conventional evolutionary theory by placing emphasis on the capacity of organisms to modify sources of natural selection in their environment (niche construction) and by broadening the evolutionary dynamic to incorporate ontogenetic and cultural processes. In this model, phenotypes have a much more active role in evolution than generally conceived. This sheds light on hominid evolution, on the evolution of culture, and on (...) altruism and cooperation. Culture amplifies the capacity of human beings to modify sources of natural selection in their environments to the point where that capacity raises some new questions about the processes of human adaptation. Key Words: adaptation; altruism; cooperation; evolutionary psychology; gene-culture coevolution; human evolution; human genetics; niche construction; sociobiology. (shrink)

We sought to evaluate whether health care professionals’ viewpoints differed on the role of ethics committees and hospitals in the resolution of clinical ethical dilemmas based on practice location. We conducted a survey study from December 21, 2013 to March 15, 2014 of health care professionals at six hospitals. The survey consisted of eight clinical ethics cases followed by statements on whether there was a role for the ethics committee or hospital in their resolution, what that role might be and (...) case specific queries. Respondents used a 5-point Likert scale to express their degree of agreement with the premises posed. We used the ANOVA test to evaluate whether respondent views significantly varied based on practice location. 240 health care professionals completed the survey. Only three individual queries of 32 showed any significant response variations across practice locations. Overall, viewpoints did not vary across practice locations within question categories on whether the ethics committee or hospital had a role in case resolution, what that role might be and case specific queries. In this multicenter survey study, the viewpoints of health care professionals on the role of ethics committees or hospitals in the resolution of clinical ethics cases varied little based on practice location. (shrink)

In spite of its success, Neo-Darwinism is faced with major conceptual barriers to further progress, deriving directly from its metaphysical foundations. Most importantly, neo-Darwinism fails to recognize a fundamental cause of evolutionary change, “niche construction”. This failure restricts the generality of evolutionary theory, and introduces inaccuracies. It also hinders the integration of evolutionary biology with neighbouring disciplines, including ecosystem ecology, developmental biology, and the human sciences. Ecology is forced to become a divided discipline, developmental biology is stubbornly difficult to reconcile (...) with evolutionary theory, and the majority of biologists and social scientists are still unhappy with evolutionary accounts of human behaviour. The incorporation of niche construction as both a cause and a product of evolution removes these disciplinary boundaries while greatly generalizing the explanatory power of evolutionary theory. (shrink)

Our response contains a definition of niche construction, illustrations of how it changes the evolutionary process, and clarifications of our conceptual model. We argue that the introduction of niche construction into evolutionary thinking earns its keep; we illustrate this argument in our discussion of rates of genetic and cultural evolution, memes and phenogenotypes, creativity, the EEA (environment of evolutionary adaptedness), and group selection.

Group selection, as advocated by Sober and Wilson, is theoretically plausible, although it remains an open question as to what extent it occurs in nature. If group selection has operated in hominids, it is likely to have selected cultural not genetic variation. A focus on niche construction helps delineate the conditions under which cooperation is favoured. Group selection may favour between-group conflict as well as within-group cooperation.

The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

BackgroundMinorities are an underrepresented population in clinical trials. A potential explanation for this underrepresentation could be lack of willingness to participate. The aim of our study was to evaluate willingness to participate in different hypothetical clinical research scenarios and to evaluate the role that predictors could have on the willingness of minorities to participate in clinical research studies.MethodsWe conducted a mixed-methods study at the Miami VA Healthcare system and included primary care patients with hypertension. We measured willingness to participate as (...) a survey of four clinical research scenarios that evaluated common study designs encountered in clinical research and that differed in degree of complexity. Our qualitative portion included comments about the scenarios.ResultsWe included 123 patients with hypertension in our study. Of the entire sample, ninety-three patients were minorities. Seventy per cent of the minorities were willing to participate, compared to 60 per cent of the non-minorities. The odds ratio of willingness to participate in simple studies was 0.58; 95 per cent CI 0.18–1.88 p=0.37 and the OR of willingness to participate in complex studies was 5.8; 95 per cent CI 1.10–1.31 p=0.03. In complex studies, minorities with low health literacy cited obtaining benefits as the most common reason to be willing to participate. Minorities who were not willing to participate, cited fear of unintended outcomes as the main reason.ConclusionsMinorities were more likely to be willing to participate in complex studies compared to non-minorities. Low health literacy and therapeutic misconception are important mediators when considering willingness to participate in clinical research. (shrink)

In this paper we will study the properties of the least extension n(Λ) of a given intermediate logic Λ by a strong negation. It is shown that the mapping from Λ to n(Λ) is a homomorphism of complete lattices, preserving and reflecting finite model property, frame-completeness, interpolation and decidability. A general characterization of those constructive logics is given which are of the form n(Λ). This summarizes results that can be found already in [13, 14] and [4]. Furthermore, we determine the (...) structure of the lattice of extensions of n(LC). (shrink)

A box type is an n-type of an o-minimal structure which is uniquely determined by the projections to the coordinate axes. We characterize heirs of box types of a polynomially bounded o-minimal structure M. From this, we deduce various structure theorems for subsets of $M^k $ , definable in the expansion M of M by all convex subsets of the line. We show that M after naming constants, is model complete provided M is model complete.

No decorrer do N século d. C. o mundo tardo antigo romano vivencia uma série de profundas transformações que alteram fundamentalmente as estruturas sociais, econômicas, políticas, religiosas e mentais clássicas fazendo surgir outras que resistimos a chamar de medievais. Dentre essas mudanças uma nos apresenta como tendo uma particular relevância e interesse, qual seja, a expansão da religião cristã no âmbito da bacia do mar Mediterrâneo, isto é, observamos um lento, mas constante processo de cristianização da sociedade tardo antiga romana. (...) Nosso trabalho tem por objetivo abordar um aspecto deste fenômeno, a saber o diálogo, o encontro e a mútua influência entre a doutrina cristã e a tradição cultural romano-helenística, através da análise do processo de transformações das ideias morais e políticas dos romanos em valores e virtudes cristãs. (shrink)

The primary purpose of this randomized controlled trial (RCT) was to evaluate the efficacy of an unguided, two-week internet-based training program to overcome procrastination, called ON.TOP. Because adherence is a typical problem among individuals who tend to procrastinate, especially with internet-based interventions, the secondary purpose of the present study was to investigate whether adding SMS support increases subjects’ frequency of engagement in training. In a three-armed RCT (N = 161), the effects of the intervention alone and intervention with daily SMS-support (...) were compared to a waiting list control condition in a sample of students. The primary outcome of interest was procrastination. The secondary outcome of interest was the extent of training behavior. Baseline (T0), immediate post-treatment (T1) and 8-week post-treatment (T2) assessments were conducted. Results indicated that procrastination decreased significantly only with intervention group with daily SMS support, relative to control. Moreover, incorporating SMS support also may enhance extent of training behavior. (shrink)

Idealism has always struggled against the hedonistic trends in philosophy which see the goal of existence in the happiness of the individual and which identify happiness with pleasure. Idealism insists that happiness is a subjective concept which makes man dependent upon chance and accident. Happiness, it holds, does not lead beyond the particular interests of the individual, whereas the progress of mankind, reason in history, demands the subordination of particular interests to the whole. So long as happiness is defined as (...) the state of satisfaction of the isolated individual, it must remain an abstract concept. It expresses the condition that the satisfaction of one individual within an antagonistic society is only possible at the expense of another. The essential relationships between men cannot be permeated with happiness when the life process of society is driven on by work for the sake of profit and mere self-preservation» when the destiny of the individual is shaped by the blind mechanism of the market. Only brief moments of immediate pleasure are possible. To the extent that hedonism holds firmly to the subjective demand for happiness in the face of the demands of a reified world, it expresses a materialist protest. This protest, however, is itself imprisoned within the antagonistic society, in that it is concerned with the satisfaction of the isolated individual.But the concept of happiness points beyond the isolation of the subject. His personal pleasure and satisfaction is not necessarily happiness, his immediate interest is not necessarily his real interest. The content of happiness is to be approached through a consideration of its truth. The needs and satisfactions of the individual are not given once and for all, but are determined by the social relationships in which they arise. Until now they have borne the stigma of universal injustice and lack of freedom. The disciplining of the masses for the modern labor process has brought with it corporal and spiritual atrophy, suppression, and incapacity for happiness. Real happiness presupposes a transformed organization of society, in which the realization of individual potentialities will no longer be diverted by internalization and no longer made meaningless by competition. In its real form, happiness is identical with freedom. It ceases to be merely a subjective feeling and becomes the real constitution of mankind.Les doctrines hédonistes de la philosophie, qui voyaient dans le bonheur le but de l’existence individuelle et qui confondaient le bonheur avec le plaisir, ont toujours été combattues par l’idéalisme. On leur opposait que le bonheur est un principe subjectif, qui soumet les hommes à l’arbitraire et au hasard. Le bonheur ne saurait être l’essentiel, car le bonheur ne mène pas au delà des intérêts particuliers des individus. Le progrès de l’humanité, la raison dans l’histoire exigent la subordination des intérêts particuliers à l’universel. Si longtemps que le bonheur est déterminé comme l’état de satisfaction de l’individu isolé, il reste un concept abstrait. Il dénote un état de fait : dans la société antagoniste, la satisfaction de l’individu n’est possible qu’aux dépens des autres. Le travail en vue du profit et de l’intérêt strictement personnel est constitutif du procès social, la destinée de l’individu dépend des mécanismes aveugles du marché : dans ces conditions toutes les relations entre les hommes ne peuvent être fondées sur le bonheur. Pour celui-ci ne subsistent que le loisir et la jouissance immédiate. Dans la mesure où l’hédonisme maintient la prétention subjective au bonheur, face aux exigences de l’universalité devenue chose, il représente une protestation matérialiste. Mais la protestation reste elle-même liée à la société contradictoire dès lors qu’elle s’arrête à la satisfaction de l’individu isolé. Le concept de bonheur dépasse l’isolement du sujet. La joie, le consentement de celui-ci n’est pas encore bonheur, son intérêt immédiat n’est pas encore son intérêt authentique. Il est légitime de poser à propos du contenu du bonheur la question de vérité. Besoins et satisfactions des individus ne sont point encore données ultimes, ils sont constitués par les rapports sociaux dans lesquels ils apparaissent. Jusqu’à ce jour dans l’histoire, les besoins portent la marque de la non-liberté et de l’injustice générales. Pour former les masses à la discipline moderne du travail, on les a mutilées physiquement et psychiquement, on les a condamnées à refouler leurs désirs. Onlesarendues dans une large mesure incapables de jouissance. Le bonheur réel suppose une forme autre de la société dans laquelle l’accomplissement des possibilités individuelles ne sera plus détourné par l’intériorisation, ni privé de sens par la concurrence. En sa figure véritable, le bonheur est identique à la liberté, il cesse d’être un état affectif purement subjectif et devient la constitution réelle de l’humanité. (shrink)

Recently, the gender asterisk has become more widespread in grammatical gender languages in order to represent all genders. Such gender-fair language is intended to help better address women and other genders and make their interests and achievements more visible. Critics often argue this would make the language less comprehensible and less aesthetically appealing. Two experiments examined the effects of the gender asterisk on text comprehensibility, aesthetic perception, and interest. N = 159 and N = 127 participants were randomly provided with (...) a text in either masculine-only form or alternatively in gender-fair language with the gender asterisk. The results of the first experiment showed no impairment of comprehensibility and aesthetic evaluation of the texts by the gender asterisk and no effect on interest in the game, while the second experiment showed significant impairments of comprehensibility, aesthetic evaluation, and interest in the game by the gender asterisk. The proportion of singular forms is discussed as a possible explanation for the different results. Experiment 1 predominantly used plural forms like die Spieler*innen and did not include forms such as der*die Spieler*in, whereas Experiment 2 included many such more complex singular forms. We argue that this issue might be crucial, and that it deserves full attention in future studies. (shrink)