Results for 'Simon E. Kolstoe'

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  1.  18
    Research approvals iceberg: helping it melt away.Simon E. Kolstoe & David Carpenter - 2019 - BMC Medical Ethics 20 (1):1-4.
    Background In their paper “Research approvals iceberg: how a ‘low-key’ study in England needed 89 professionals to approve it and how we can do better” Petrova and Barclay highlight concerns with the health research regulatory environment in the UK. Discussion As long-standing chairs of NHS research ethics committees, researchers, and also academics in research ethics, we are also often frustrated with the regulatory process in the UK. However, we think that Petrova and Barclay’s analysis is misleading because it conflates research (...)
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  2.  9
    Research approvals iceberg: helping it melt away.Simon E. Kolstoe & David Carpenter - 2019 - BMC Medical Ethics 20 (1):1-4.
    In their paper “Research approvals iceberg: how a ‘low-key’ study in England needed 89 professionals to approve it and how we can do better” Petrova and Barclay highlight concerns with the health research regulatory environment in the UK. As long-standing chairs of NHS research ethics committees, researchers, and also academics in research ethics, we are also often frustrated with the regulatory process in the UK. However, we think that Petrova and Barclay’s analysis is misleading because it conflates research ethics with (...)
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  3.  16
    Incision or insertion makes a medical intervention invasive. Commentary on ‘What makes a medical intervention invasive?’.Paul Affleck, Julia Cons & Simon E. Kolstoe - 2024 - Journal of Medical Ethics 50 (4):242-243.
    De Marco and colleagues claim that the standard account of invasiveness as commonly encountered ‘…does not capture all uses of the term in relation to medical interventions1 ’. This is open to challenge. Their first example is ‘non-invasive prenatal testing’. Because it involves puncturing the skin to obtain blood, De Marco et al take this as an example of how an incision or insertion is not sufficient to make an intervention invasive; here is a procedure that involves an incision, but (...)
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  4.  9
    Reshaping consent so we might improve participant choice (III) – How is the research participant’s understanding currently checked and how might we improve this process?Hugh Davies, Simon E. Kolstoe & Anthony Lockett - forthcoming - Research Ethics.
    Valid consent requires the potential research participant understands the information provided. We examined current practice in 50 proposed Clinical Trials of Investigational Medicinal Products to determine how this understanding is checked. The majority of the proposals ( n = 44) indicated confirmation of understanding would take place during an interactive conversation between the researcher and potential participant, containing questions to assess and establish understanding. Yet up until now, research design and review have not focussed upon this, concentrating more on written (...)
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  5.  16
    Reshaping consent so we might improve participant choice (II) – helping people decide.Hugh Davies, Rosie Munday, Maeve O’Reilly, Catriona Gilmour Hamilton, Arzhang Ardahan, Simon E. Kolstoe & Katie Gillies - 2023 - Research Ethics 19 (4):466-473.
    Research consent processes must provide potential participants with the necessary information to help them decide if they wish to join a study. On the Oxford ‘A’ Research Ethics Committee we’ve found that current research proposals mostly provide adequate detail (even if not in an easily comprehensible format), but often fail to support decision making, a view supported by published evidence. In a previous paper, we described how consent might be structured, and here we develop the concept of an Information and (...)
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  6.  18
    ‘The ethics approval took 20 months on a trial which was meant to help terminally ill cancer patients. In the end we had to send the funding back’: a survey of views on human research ethics reviews.Anna Mae Scott, Iain Chalmers, Adrian Barnett, Alexandre Stephens, Simon E. Kolstoe, Justin Clark & Paul Glasziou - 2021 - Journal of Medical Ethics 47 (12):e90-e90.
    BackgroundWe conducted a survey to identify what types of health/medical research could be exempt from research ethics reviews in Australia.MethodsWe surveyed Australian health/medical researchers and Human Research Ethics Committee members. The survey asked whether respondents had previously changed or abandoned a project anticipating difficulties obtaining ethics approval, and presented eight research scenarios, asking whether these scenarios should or should not be exempt from ethics review, and to provide comments. Qualitative data were analysed thematically; quantitative data in R.ResultsWe received 514 responses. (...)
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  7.  41
    Tangled webs: tracing the connections between genes and cognition.Simon E. Fisher - 2006 - Cognition 101 (2):270-297.
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  8.  16
    Connecting genes with cognition.Simon E. Fisher & Clyde Francks - 2006 - Trends in Cognitive Sciences 10 (6):250-257.
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  9. Das Wahre ist der bacchantische Taumel, an dem kein Glied nicht trunken ist: Bemerkungen zu einem Hegelschen Anfangs-Satz und Wahrspruch.E. Simons - 1996 - Philosophisches Jahrbuch 103 (2):366-372.
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  10. ""'Das Wahre-ist-der-bacchantische-Taumel-an-dem-kein-Glied-nicht-trunken-ist", observations on Hegel's opening sentence and the definition of truth in'Phanomenologie des Geistes.E. Simons - 1996 - Philosophisches Jahrbuch 103 (2):366-372.
     
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  11.  16
    Ab-initioinvestigation of RKKY interactions on metallic surfaces.E. Simon, B. Lazarovits, L. Szunyogh & B. Újfalussy - 2008 - Philosophical Magazine 88 (18-20):2667-2672.
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  12.  9
    Moshe Brill: 1910-1943.E. Simon - 1944 - Psychological Review 51 (3):200-200.
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  13.  12
    Octavian and the thunderbolt: The temple of Apollo Palatinus and Roman traditions of temple building.E. Simon - 2006 - Classical Quarterly 56:149-168.
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  14. Une métaphysique tragique.Émile Simon - 1951 - [Paris]: Gallimard.
  15.  20
    Trials are already being prioritised, just not at the institutional level.Simon Kolstoe - 2017 - Journal of Medical Ethics 43 (12):814-815.
    Successful clinical trials are important for all of us, but they can be extremely complicated to design and run, so work must be done to consider what commonly goes wrong and how these issues can be addressed. Gelinas et al suggest an ethical argument for institutional prioritisation of clinical trials conducted among limited populations. This is to ensure successful recruitment and prevent competing trials rendering each other irrelevant through lack of statistical power. But they overlook the fact that effective prioritisation (...)
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  16.  37
    I think therefore I am: Rest-related prefrontal cortex neural activity is involved in generating the sense of self.M. Gruberger, Y. Levkovitz, T. Hendler, E. V. Harel, H. Harari, E. Ben Simon, H. Sharon & A. Zangen - 2015 - Consciousness and Cognition 33:414-421.
  17.  22
    Measuring inconsistency in research ethics committee review.Samantha Trace & Simon Erik Kolstoe - 2017 - BMC Medical Ethics 18 (1):1-10.
    Background The review of human participant research by Research Ethics Committees or Institutional Review Boards is a complex multi-faceted process that cannot be reduced to an algorithm. However, this does not give RECs/ IRBs permission to be inconsistent in their specific requirements to researchers or in their final opinions. In England the Health Research Authority coordinates 67 committees, and has adopted a consistency improvement plan including a process called “Shared Ethical Debate” where multiple committees review the same project. Committee reviews (...)
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  18.  21
    Measuring inconsistency in research ethics committee review.Samantha Trace & Simon Erik Kolstoe - 2017 - BMC Medical Ethics 18 (1):65.
    The review of human participant research by Research Ethics Committees or Institutional Review Boards is a complex multi-faceted process that cannot be reduced to an algorithm. However, this does not give RECs/ IRBs permission to be inconsistent in their specific requirements to researchers or in their final opinions. In England the Health Research Authority coordinates 67 committees, and has adopted a consistency improvement plan including a process called “Shared Ethical Debate” where multiple committees review the same project. Committee reviews are (...)
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  19.  15
    Assessing the effects of common variation in the FOXP2 gene on human brain structure.Martine Hoogman, Tulio Guadalupe, Marcel P. Zwiers, Patricia Klarenbeek, Clyde Francks & Simon E. Fisher - 2014 - Frontiers in Human Neuroscience 8.
  20.  29
    Can UK NHS research ethics committees effectively monitor publication and outcome reporting bias?Rasheda Begum & Simon Kolstoe - 2015 - BMC Medical Ethics 16 (1):1-5.
    BackgroundPublication and outcome reporting bias is often caused by researchers selectively choosing which scientific results and outcomes to publish. This behaviour is ethically significant as it distorts the literature used for future scientific or clinical decision-making. This study investigates the practicalities of using ethics applications submitted to a UK National Health Service research ethics committee to monitor both types of reporting bias.MethodsAs part of an internal audit we accessed research ethics database records for studies submitting an end of study declaration (...)
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  21.  39
    Differences in cerebral cortical anatomy of left- and right-handers.Tulio Guadalupe, Roel M. Willems, Marcel P. Zwiers, Alejandro Arias Vasquez, Martine Hoogman, Peter Hagoort, Guillen Fernandez, Jan Buitelaar, Barbara Franke, Simon E. Fisher & Clyde Francks - 2014 - Frontiers in Psychology 5.
  22.  29
    Reviewing code consistency is important, but research ethics committees must also make a judgement on scientific justification, methodological approach and competency of the research team.Samantha Trace & Simon Kolstoe - 2018 - Journal of Medical Ethics 44 (12):874-875.
    We have followed with interest the commentaries arising from Moore and Donnellys1 argument that authorities in charge of research ethics committees should focus primarily on establishing code-consistent reviews.1 We broadly agree with Savulescu’s2 argument that ethics committees should become more expert, but in a different way and for a different reason. We have recently been working with the UK Health Research Authority analysing the outcomes of their ‘Shared Ethical Debate’ exercises.3 Each ShED exercise involves the circulation of a single research (...)
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  23. The Problem of Hidden Variables in Quantum Mechanics.Simon Kochen & E. P. Specker - 1967 - Journal of Mathematics and Mechanics 17:59--87.
  24.  11
    Do microenvironmental changes disrupt multicellular organisation with ageing, enacting and favouring the cancer cell phenotype?Simon P. Castillo, Juan E. Keymer & Pablo A. Marquet - 2021 - Bioessays 43 (2):2000126.
    Cancer is a singular cellular state, the emergence of which destabilises the homeostasis reached through the evolution to multicellularity. We present the idea that the onset of the cellular disobedience to the metazoan functional and structural architecture, known as the cancer phenotype, is triggered by changes in the cell's external environment that occur with ageing: what ensues is a breach of the social contract of multicellular life characteristic of metazoans. By integrating old ideas with new evidence, we propose that with (...)
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  25.  42
    Logical Structures Arising in Quantum Theory.Simon Kochen, E. P. Specker, C. A. Hooker & P. D. Finch - 1985 - Journal of Symbolic Logic 50 (2):558-566.
  26. Exorcising Grice’s ghost: an empirical approach to studying intentional communication in animals.Simon W. Townsend, Sonja E. Koski, Richard W. Byrne, Katie E. Slocombe, Balthasar Bickel, Markus Boeckle, Ines Braga Goncalves, Judith M. Burkart, Tom Flower, Florence Gaunet, Hans Johann Https://Orcidorg909X Glock, Thibaud Gruber, David A. W. A. M. Jansen, Katja Liebal, Angelika Linke, Ádám Miklósi, Richard Moore, Carel P. van Schaik, Sabine Stoll, Alex Vail, Bridget M. Waller, Markus Wild, Klaus Zuberbühler & Marta B. Manser - 2016 - Biological Reviews 3.
    Language’s intentional nature has been highlighted as a crucial feature distinguishing it from other communication systems. Specifically, language is often thought to depend on highly structured intentional action and mutual mindreading by a communicator and recipient. Whilst similar abilities in animals can shed light on the evolution of intentionality, they remain challenging to detect unambiguously. We revisit animal intentional communication and suggest that progress in identifying analogous capacities has been complicated by (i) the assumption that intentional (that is, voluntary) production (...)
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  27.  56
    Therapeutic Misconception: Hope, Trust and Misconception in Paediatric Research.Simon Woods, Lynn E. Hagger & Pauline McCormack - 2014 - Health Care Analysis 22 (1):3-21.
    Although the therapeutic misconception (TM) has been well described over a period of approximately 20 years, there has been disagreement about its implications for informed consent to research. In this paper we review some of the history and debate over the ethical implications of TM but also bring a new perspective to those debates. Drawing upon our experience of working in the context of translational research for rare childhood diseases such as Duchenne muscular dystrophy, we consider the ethical and legal (...)
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  28.  38
    Researcher Views on Changes in Personality, Mood, and Behavior in Next-Generation Deep Brain Stimulation.Peter Zuk, Clarissa E. Sanchez, Kristin Kostick-Quenet, Katrina A. Muñoz, Lavina Kalwani, Richa Lavingia, Laura Torgerson, Demetrio Sierra-Mercado, Jill O. Robinson, Stacey Pereira, Simon Outram, Barbara A. Koenig, Amy L. McGuire & Gabriel Lázaro-Muñoz - 2023 - American Journal of Bioethics Neuroscience 14 (3):287-299.
    The literature on deep brain stimulation (DBS) and adaptive DBS (aDBS) raises concerns that these technologies may affect personality, mood, and behavior. We conducted semi-structured interviews with researchers (n = 23) involved in developing next-generation DBS systems, exploring their perspectives on ethics and policy topics including whether DBS/aDBS can cause such changes. The majority of researchers reported being aware of personality, mood, or behavioral (PMB) changes in recipients of DBS/aDBS. Researchers offered varying estimates of the frequency of PMB changes. A (...)
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  29. Wissenschaftstheorie am Ende der 80er Jahre. Einführende Bemerkungen in Wissenschaftstheorie am Ende der 80er Jahre.E. Morscher & P. Simons - 1988 - Philosophia Naturalis 25 (3-4):229-238.
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  30.  5
    Question of the Month.Nicholas B. Taylor, Michael Brake, Simon Kolstoe, Bruce Robertson & Nella Leontieva - 2018 - Philosophy Now 129:54-56.
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  31.  14
    Athlete Experiences of Shame and Guilt: Initial Psychometric Properties of the Athletic Perceptions of Performance Scale Within Junior Elite Cricketers.Simon M. Rice, Matt S. Treeby, Lisa Olive, Anna E. Saw, Alex Kountouris, Michael Lloyd, Greg Macleod, John W. Orchard, Peter Clarke, Kate Gwyther & Rosemary Purcell - 2021 - Frontiers in Psychology 12.
    Guilt and shame are self-conscious emotions with implications for mental health, social and occupational functioning, and the effectiveness of sports practice. To date, the assessment and role of athlete-specific guilt and shame has been under-researched. Reporting data from 174 junior elite cricketers, the present study utilized exploratory factor analysis in validating the Athletic Perceptions of Performance Scale, assessing three distinct and statistically reliable factors: athletic shame-proneness, guilt-proneness, and no-concern. Conditional process analysis indicated that APPS shame-proneness mediated the relationship between general (...)
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  32. Brill Online Books and Journals.Simon Tugwell, Anne Davenport, Richard Cross, Andrew E. Larsen, Joke Spruyt & Kent Emery - 1999 - Vivarium 37 (2).
     
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  33. Behavioral, neuroimaging, and neuropsychological approaches to implicit perception.Daniel J. Simons, Deborah E. Hannula, David E. Warren & Steven W. Day - 2007 - In Philip David Zelazo, Morris Moscovitch & Evan Thompson (eds.), Cambridge Handbook of Consciousness. Cambridge: Cambridge University Press.
  34.  20
    Differences in time-based task characteristics help to explain the age-prospective memory paradox.Simon J. Haines, Susan E. Randall, Gill Terrett, Lucy Busija, Gemma Tatangelo, Skye N. McLennan, Nathan S. Rose, Matthias Kliegel, Julie D. Henry & Peter G. Rendell - 2020 - Cognition 202 (C):104305.
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  35. Flexibility in the development of action.E. Adolph Karen, S. Joh Amy, M. Franchak John, Simone Shaziela Ishak & V. Gill - 2008 - In Ezequiel Morsella, John A. Bargh & Peter M. Gollwitzer (eds.), Oxford handbook of human action. New York: Oxford University Press.
     
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  36.  92
    Constructing a Reward-Related Quality of Life Statistic in Daily Life—a Proof of Concept Study Using Positive Affect.Simone J. W. Verhagen, Claudia J. P. Simons, Catherine van Zelst & Philippe A. E. G. Delespaul - 2017 - Frontiers in Psychology 8:294592.
    Background: Mental healthcare needs person-tailored interventions. Experience Sampling Method (ESM) can provide daily life monitoring of personal experiences. This study aims to operationalize and test a measure of momentary reward-related Quality of Life (rQoL). Intuitively, quality of life improves by spending more time on rewarding experiences. ESM clinical interventions can use this information to coach patients to find a realistic, optimal balance of positive experiences (maximize reward) in daily life. rQoL combines the frequency of engaging in a relevant context (a (...)
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  37.  34
    Researcher Perspectives on Data Sharing in Deep Brain Stimulation.Peter Zuk, Clarissa E. Sanchez, Kristin Kostick, Laura Torgerson, Katrina A. Muñoz, Rebecca Hsu, Lavina Kalwani, Demetrio Sierra-Mercado, Jill O. Robinson, Simon Outram, Barbara A. Koenig, Stacey Pereira, Amy L. McGuire & Gabriel Lázaro-Muñoz - 2020 - Frontiers in Human Neuroscience 14:578687.
    The expansion of research on deep brain stimulation (DBS) and adaptive DBS (aDBS) raises important neuroethics and policy questions related to data sharing. However, there has been little empirical research on the perspectives of experts developing these technologies. We conducted semi-structured, open-ended interviews with aDBS researchers regarding their data sharing practices and their perspectives on ethical and policy issues related to sharing. Researchers expressed support for and a commitment to sharing, with most saying that they were either sharing their data (...)
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  38.  21
    Hebrew Bible Manuscripts in the Cambridge Genizah Collections, Volume I: Taylor-Schechter Old Series and Other Genizah Collections in Cambridge University LibraryA Miscellany of Literary Pieces from the Cambridge Genizah Collections. A Catalogue and Selection of Texts in the Taylor-Schechter Collection, Old Series, Box A45.E. J. Revell, M. C. Davis & Simon Hopkins - 1981 - Journal of the American Oriental Society 101 (2):260.
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  39.  10
    Why Deliberation and Voting Belong Together.Simone Chambers & Mark E. Warren - forthcoming - Res Publica:1-19.
    The field of deliberative democracy now generally recognizes the co-dependence of deliberation and voting. The field tends to emphasize what deliberation accomplishes for vote-based decisions. In this paper, we reverse this now common view to ask: In what ways does voting benefit deliberation? We discuss seven ways voting can complement and sometimes enhance deliberation. First, voting furnishes deliberation with a feasible and fair closure mechanism. Second, the power to vote implies equal recognition and status, both morally and strategically, which is (...)
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  40.  5
    Scientific discovery and simplicity of method.Herbert A. Simon, Raúl E. Valdés-Pérez & Derek H. Sleeman - 1997 - Artificial Intelligence 91 (2):177-181.
  41.  21
    Directing spatial attention to locations within remembered and imagined mental representations.Simon G. Gosling & Duncan E. Astle - 2013 - Frontiers in Human Neuroscience 7.
  42. A Theology of Salvation: A Commentary on Isaiah 40–55.Ulrich E. Simon - 1953
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  43.  27
    Lectures on philosophy.Simone Weil - 1978 - New York: Cambridge University Press.
    Simone Weil's Leçons de Philosophie are derived from a course she taught at the lyce;e for girls at Roanne in 1933-4. Anne Reynaud-Gue;rithault was a pupil in the class; her notes are not a verbatim record but are a very full and, as far as one can judge, faithful rendering, often catching the unmistakable tone of Simone Weil's voice as well as the force and the directness of her thought. The lectures form a good general introduction to philosophy, ranging widely (...)
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  44. Authentic Leadership and Behavioral Integrity as Drivers of Follower Commitment and Performance.Hannes Leroy, Michael E. Palanski & Tony Simons - 2012 - Journal of Business Ethics 107 (3):255-264.
    The literatures on both authentic leadership and behavioral integrity have argued that leader integrity drives follower performance. Yet, despite overlap in conceptualization and mechanisms, no research has investigated how authentic leadership and behavioral integrity relate to one another in driving follower performance. In this study, we propose and test the notion that authentic leadership behavior is an antecedent to perceptions of leader behavioral integrity, which in turn affects follower affective organizational commitment and follower work role performance. Analysis of a survey (...)
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  45.  15
    Prioritization of Referrals in Outpatient Physiotherapy Departments in Québec and Implications for Equity in Access.Simon Deslauriers, Marie-Hélène Raymond, Maude Laliberté, Anne Hudon, François Desmeules, Debbie E. Feldman & Kadija Perreault - unknown
    In the context of long waiting time to access rehabilitation services, a large majority of settings use referral prioritization to help manage waiting lists. Prioritization practices vary greatly between settings and there is little consensus on how best to prioritize referrals. This paper describes the prioritization processes for physiotherapy services in Québec and its potential implications in terms of equity in access to services. This is a secondary analysis of a survey of outpatient physiotherapy departments (n=98; proportion of participation was (...)
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  46.  9
    Prioritization of Referrals in Outpatient Physiotherpay Departments in Québec and Implications for Equity in Access.Simon Deslauriers, Marie-Hélène Raymond, Maude Laliberté, Anne Hudon, François Desmeules, Debbie E. Feldman & Kadija Perreault - 2018 - Canadian Journal of Bioethics/Revue canadienne de bioéthique 1 (3):49-60.
    In the context of long waiting time to access rehabilitation services, a large majority of settings use referral prioritization to help manage waiting lists. Prioritization practices vary greatly between settings and there is little consensus on how best to prioritize referrals. This paper describes the prioritization processes for physiotherapy services in Québec and its potential implications in terms of equity in access to services. This is a secondary analysis of a survey of outpatient physiotherapy departments conducted in 2015 across publicly (...)
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  47.  43
    “Aha!” is stronger when preceded by a “huh?”: presentation of a solution affects ratings of aha experience conditional on accuracy.Margaret E. Webb, Simon J. Cropper & Daniel R. Little - 2019 - Thinking and Reasoning 25 (3):324-364.
    Insight has been investigated under the assumption that participants solve insight problems with insight processes and/or experiences. A recent trend has involved presenting participants with the solution and analysing the resultant experience as if insight has taken place. We examined self-reports of the aha experience, a defining aspect of insight, before and after feedback, along with additional affective components of insight (e.g., pleasure, surprise, impasse). Classic insight problems, compound remote associates, and non-insight problems were randomly interleaved and presented to participants. (...)
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  48.  13
    Buddhism, Virtue and Environment.David E. Cooper & Simon P. James - 2005 - Routledge.
    Buddhism, one increasingly hears, is an 'eco-friendly' religion. It is often said that this is because it promotes an 'ecological' view of things, one stressing the essential unity of human beings and the natural world. Buddhism, Virtue and Environment presents a different view. While agreeing that Buddhism is, in many important respects, in tune with environmental concerns, Cooper and James argue that what makes it 'green' is its view of human life. The true connection between the religion and environmental thought (...)
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  49.  9
    Reframing masculinity and fatherhood: Narratives on faith-based values in (re)shaping ‘coloured’ fathers.Fazel E. Freeks, Simone M. Peters & Helenard Louw - 2022 - HTS Theological Studies 78 (1):9.
    Stereotypes of ‘coloured’ men from marginalised communities in the Western Cape, South Africa, portray these men as violent, lazy, alcoholics, domestic and substance abusers and absent in the lives of their children. Although extensive research has been conducted on fathers and fatherhood, there is still a lack of positive constructions and representations of fatherhood. In narrative interviews with 11 fathers who reside in the Cape Flats, faith-based values were understood as possible restorative avenues for fathers. This article explores how faith-based (...)
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  50. Precautionary Paralysis.J. E. H. Simon - manuscript
    A brief examination of the self-negating quality of the precautionary principle within the context of environmental ethics, and its consequent failure, as an ethical guide, to justify large-scale regulation of atmospheric cabon dioxide emissions.
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