SummaryIn the 1940s a controversy developed between John H. Northrop (Nobel Laureate, 1946) and Max Delbrück (Nobel Laureate, 1969) on the formation of bacteriophage. From the historiography of molecular biology there emerges a picture of an obstinate Northrop who repudiated the ‘correct’ insights revealed by the experiments of Delbrück. The established reputation of Northrop confronts one with the question of why Delbrück's epoch-making experiments were not convincing for Northrop. It will be argued that this was a consequence of local incommensurability (...) between Northrop's physiological/chemical research style and Delbrück's bacteriological/genetic research style. The analysis of this controversy reveals the elements that made up these two research styles. (shrink)

This paper examines the vital role played by electron microscopy toward the modern definition of viruses, as formulated in the late 1950s. Before the 1930s viruses could neither be visualized by available technologies nor grown in artificial media. As such they were usually identified by their ability to cause diseases in their hosts and defined in such negative terms as “ultramicroscopic” or invisible infectious agents that could not be cultivated outside living cells. The invention of the electron microscope, with magnification (...) and resolution powers several orders of magnitude better than that of optical instruments, opened up possibilities for biological applications. The hitherto invisible viruses lent themselves especially well to investigation with this new instrument. We first offer a historical consideration of the development of the instrument and, more significantly, advances in techniques for preparing and observing specimens that turned the electron microscope into a routine biological tool. We then describe the ways in which the electron microscopic images, or micrographs, functioned as forms of new knowledge about viruses and resulted in a paradigm shift in the very definition of these entities. Micrographs were not mere illustrations since they did the work for the electron microscopists. Drawing extensively on primary publications, we adduce the role of the new instrument in understanding the so-called eclipse phase in virus multiplication and the unexpected spinoffs of data from electron microscopy in naming and classifying viruses. Thus, we show that electron microscopy functioned not only to provide evidence, but also arguments in facilitating a reordering of the world that it brought into the visual realm. (shrink)

This paper examines the vital role played by electron microscopy toward the modern definition of viruses, as formulated in the late 1950s. Before the 1930s viruses could neither be visualized by available technologies nor grown in artificial media. As such they were usually identified by their ability to cause diseases in their hosts and defined in such negative terms as “ultramicroscopic” or invisible infectious agents that could not be cultivated outside living cells. The invention of the electron microscope, with magnification (...) and resolution powers several orders of magnitude better than that of optical instruments, opened up possibilities for biological applications. The hitherto invisible viruses lent themselves especially well to investigation with this new instrument. We first offer a historical consideration of the development of the instrument and, more significantly, advances in techniques for preparing and observing specimens that turned the electron microscope into a routine biological tool. We then describe the ways in which the electron microscopic images, or micrographs, functioned as forms of new knowledge about viruses and resulted in a paradigm shift in the very definition of these entities. Micrographs were not mere illustrations since they did the work for the electron microscopists. Drawing extensively on primary publications, we adduce the role of the new instrument in understanding the so-called eclipse phase in virus multiplication and the unexpected spinoffs of data from electron microscopy in naming and classifying viruses. Thus, we show that electron microscopy functioned not only to provide evidence, but also arguments in facilitating a reordering of the world that it brought into the visual realm. (shrink)

In his early work, the philosopher Stanley Cavell offers a sustained engagement with the threat of epistemological scepticism, shaped by the intuition that although (as the late Wittgenstein shows) ordinary language use is the practice within which alone meaning is possible (and which can thus not be further analysed or rationalised), it is also a basic human inclination to wish to escape the limitations of the ‘ordinary’. This, for Cavell, is the root of scepticism. Scepticism, on this view, thus appears (...) not primarily as an epistemological but as an (injurious) moral stance, which cannot be refuted but must be continually confronted and overcome. Vis-à-vis scepticism, ‘acknowledgement’ is the practice-based recognition of the world and other people in their continuing elusiveness, which ineluctably involves risk, but just so is the only way of knowing that is appropriate to and honours the (finite) human condition. One problematic aspect of this (very fertile) approach is that Cavell’s secular viewpoint makes it difficult for him to say both why the desire for a ‘beyond’ arises in the first place, and why its expression as denial is morally wrong (rather than merely misguided). His approach thus invites a theological ‘supplementation’ which grounds the human condition in an original and real relation to God that is meant to draw the believer, through Christ, into the divine life itself. Such a reinterpretation both elucidates the concepts of scepticism and acknowledgement, and makes these concepts available for a theological outlook that is able to accommodate Cavell’s profound insights into ‘the human’. (shrink)

Kritische bijdragen over ideologisch gekleurde vormen van westerse culturele antropologie.

Theorie en de praktijk, geënt op filosofieën en mediatatie-methoden uit Zen-kloosters en Hindoe-ashrams.

Inleiding tot de fenomenologische methode van werkelijkheidsbenadering.

Miracle narratives are an essential part of nearly all religious traditions. The importance of miracles also applies to Christianity. The Gospels record thirty-five miracles that Jesus is said to have performed, including twenty-three miraculous healings and nine nature miracles (for example, stilling a storm and turning water into wine). At the heart of Christian faith lies the story of Jesus' resurrection from the dead. However, the factuality of these events has been increasingly problematised, especially since the period of the Enlightenment. (...) In this study, it is argued that the current debate between science-oriented critics of miracles and their religious opponents focuses predominantly on the question of factuality and evidence at the loss of the religious meaning of miracles. The suggestion that science and religion would be opposite approaches is denied in a proposal of a balanced hermeneutical approach of miracles that does justice to scientific findings, religious texts and experience. (shrink)

For further development of organic agriculture, it will become increasingly essential to integrate experienced innovative practitioners in research projects. The characteristics of this process of co-learning have been transformed into a research approach, theoretically conceptualized as “experiential science” (Baars 2007 , Baars and Baars 2007 ). The approach integrates social sciences, natural sciences, and human sciences. It is derived from action research and belongs to the wider field of transdiscliplinary research. In a dialogue-based culture of equality and mutual exchange the (...) principal of a “bottom-up” experiential learning process can be stimulated and fully reflective. It provides an opportunity to develop organic agriculture as multiple best-practices based on transdisciplinary projects, cases studies, and case series. The aim of the article is to describe the methodological characteristics and the theoretical and practical potential of experiential science for research in and development of organic farming. Three characteristic projects are outlined to illustrate the main elements of the methodology: the retrospective reflection on intuitive and experiential knowledge held by farmers; the knowledge derived from on-farm experimentation; the exchange of knowledge and experiences between farming pioneers within a “masterclass” setting. The study concludes that experiential science offers an important philosophical reconciliation process whereby a synthesis of different approaches to research becomes possible in solving real-life problems: quantitative and qualitative, subjective and objective, reductionistic and holistic, practice and science. Recognizing that there are multiple elements contributing to the process of acquiring knowledge, experiential science draws on a broad field of scientific methods thereby integrating the hermeneutic approach of social sciences and the Humanities with the established methods of contemporary natural science. (shrink)

Cultuurfilosofisch essay over onze verhouding tot de natuur.

Cet ouvrage constitue une introduction à la pensée politique de Raymond Aron (1905-1983). Après être revenu sur l'itinéraire intellectuel et politique complexe de celui qui se définissait comme un " spectateur engagé ", il présente et analyse ses contributions à différents champs du savoir : la sociologie des sociétés modernes, la théorie des régimes politiques, la philosophie politique, l'étude des relations internationales et la philosophie de l'histoire. Ce livre a pour ambition de faciliter l'accès d'une nouvelle génération de lecteurs à (...) la pensée de ce " classique méconnu ". Il repose sur une relecture qui se veut distanciée et sereine de l'ensemble de l'œuvre, et sur la prise en compte des acquis récents de la recherche française et internationale. Ce faisant, il vise aussi à dresser un panorama des différentes interprétations se déployant actuellement au sein des études aroniennes. (shrink)

Represents the first volume to consider the modern role of holism as a central anthropological concern across a wide range of anthropological traditions ...

Logicians treat assertions as true, believed or merely hypothesized sentences. The reasoner who uses them, however, is the sole referee who can validate their truth, their aptness to describe an actual situation, their strength (as beliefs) or the relevance of their use in the current logical context. Moreover, the reasoner actively counts on these factors, as part of the reasoning process itself, and should normally be capable, when asked to do so, to assign consistently relative strengths to the assertions used. (...) The paper assumes, first, that assertions have -each- an associated, measurable strength, and that, second, this strength has significant -and measurable- effects on the truth of the sentences, the validity of the conclusion and the soundness of the reasoning. The concepts and formulas required for this are explored, and a semantics and proof theory for a sentential calculus of assertions are proposed as a natural extension of ordinary two-valued reasoning. The resulting theory, though reminiscent of Probability,is autonomous, self-contained and of a purely logical nature. (shrink)

There has been a time in my teaching career that I used to cite in my introductory classes ‘Moral Philosophy’ from Erica Jong's Fear of Flying . The situation leading up to the quote is that the main character, Isadora, is asked a sexual favour by her brother in law, Pierre. Her answer and the subsequent dialogue read then as follows: ‘I can't’ , I said. ‘Come on,’ Pierre said, ‘I'll teach you.’ ‘I didn't mean that … I meant that (...) I can't; morally , I can…’. (shrink)