This article is written from within the Catholic, and more particularly the Augustinian/Thomist tradition of moral theology. It analyses the response of the Catholic Magisterium to the prospect of germline-genetic engineering (GGE). This is a very new issue and the Church has little definitive teaching on it. The statements of Popes and Vatican congregations or commissions have not settled the key questions. An analysis of theological themes drawn from secular writers points beyond pragmatic safety considerations toward intrinsic ethical limits to (...) GGE. Given the impossibility of identifying would-have-been-created persons who would be “treated” by this intervention, altering the human genome for the sake of future generations cannot be regarded as “therapy.” Further theological considerations suggest that GGE may not be morally permissible, even in the case of identifiable genetic diseases. This is an area where more theological reflection is needed. (shrink)

It is characteristic of A. to use words that occur only once in Homer, and such a word is ρρητος. In Od. 14. 466 it describes the remark that is better left unspoken, πέρ τ' ρρητον μεινον. But it has the distinction of occurring once also in Hesiod, and this time it is used of men without fame, ητοί τ' ρρητοί τε Διòς μεγάλοιο κατι . It is clearly this line in Hesiod's proem that A. is echoing in his own, (...) and in the same kind of sense, though, as Martin points out, A. ‘renverse en quelque sorte une expression d'Hésiode’. In the Phaenomena it is Zeus who is always being celebrated by men. The idiom with ν and negative is used by Plato, Lg. 793 b, οτε νόμους δε προσαγορεύειν ατ οτε ρρητα ν, and it may have been a familiar expression. But here in A., with the emphatic οδέποτε, it does seem rather contrived, and this may account for the fanciful explanation in the scholia that Zeus here represents the air we use every time we speak. The phrasing is certainly designed to give the maximum emphasis to ρρητον, which comes in enjambement at the beginning of the second line and is then followed by a strong sense pause. It is tempting, therefore, to suggest that the poet is indulging in a kind of pun on the sound of his own name, which usually has a long α in its first syllable and sometines η in its second: e.g. Call. Epigr. 27. 4 ρήτου σύντονος γρυπνίη, and Leonidas, A.P. 9. 25. 1 γράμμα τόδ' ρήτοιο δαήμονος. Other Hellenistic poets have contrived puns on the derivation oftheir names: Philodemusin A.P. 5. 115, Meleager in A.P. 12. 165, and Crates in A.P. 11. 218. 4. Closer to A. is the story recorded in the ancient biographical tradition of Antigonus complimenting the poet with the pun εδοξóτερον ποιες τòν Eδοξον. (shrink)

The traditional interpretation of line 149 understands in praecipiti as a metaphor expressing the height that vice has reached in Juvenal's day. Vice is now ‘at its zenith’, ‘at its highest point’, ‘auf demGipfel’, ‘at its acme’, ‘a son comble’, ‘at a climax’, ‘at a dizzy height’. Lewis and Short have a special sub-heading, II. B. 3. b., for this example of praeceps and translate ‘at its point of culmination’.

THE clue to the meaning and interpretation of this poem, which has long been the despair of critics, is, I believe, to be found in a variant on line 9, faithfully preserved in the Codex Sangermanensis and yet unaccountably neglected hitherto. G's text I transcribe from M. Chatelain's photo-lithograph facsimile of the manuscript.

Contained in this rather short but quite excellent Clarke F. Ansley Award winning work is a skillful presentation of an intriguing thesis: Spinoza’s definition and criterion of truth follows neither the strictly correspondence nor the strictly coherence lines which many commentators have suspected. Rather, says Mark, Spinoza’s doctrine follows the "ontological" view of truth, prevalent in ancient and medieval times. To be true is to be a being, a thing which "is." It is the author’s contention that there are (...) texts which seem to be evidence in favor of interpreting Spinoza’s doctrine along the lines of a correspondence theory, and there are still other texts which seem to betray a kind of family resemblance to the coherence theory of truth. Most commentators, says Mark, have either focused their entire attention on one or the other of these sets of texts, or else pointed out the discrepancy and went on to something else. But what Mark here suggests to us is a rather bold and interesting approach, which, to Mark’s mind, accomplishes the task of facing squarely both sets of texts without compromising either, and without reducing Spinoza to contradiction. (shrink)

Contained in this rather short but quite excellent Clarke F. Ansley Award winning work is a skillful presentation of an intriguing thesis: Spinoza’s definition and criterion of truth follows neither the strictly correspondence nor the strictly coherence lines which many commentators have suspected. Rather, says Mark, Spinoza’s doctrine follows the "ontological" view of truth, prevalent in ancient and medieval times. To be true is to be a being, a thing which "is." It is the author’s contention that there are (...) texts which seem to be evidence in favor of interpreting Spinoza’s doctrine along the lines of a correspondence theory, and there are still other texts which seem to betray a kind of family resemblance to the coherence theory of truth. Most commentators, says Mark, have either focused their entire attention on one or the other of these sets of texts, or else pointed out the discrepancy and went on to something else. But what Mark here suggests to us is a rather bold and interesting approach, which, to Mark’s mind, accomplishes the task of facing squarely both sets of texts without compromising either, and without reducing Spinoza to contradiction. (shrink)

The goal of perception is to infer the most plausible source of sensory stimulation. Unisensory perception of temporal order, however, appears to require no inference, since the order of events can be uniquely determined from the order in which sensory signals arrive. Here we demonstrate a novel perceptual illusion that casts doubt on this intuition: in three studies (N=607) the experienced event timings are determined by causality in real-time. Adult observers viewed a simple three-item sequence ACB, which is typically remembered (...) as ABC (Bechlivanidis & Lagnado, 2016), in line with principles of causality. When asked to indicate the time at which events B and C occurred, points of subjective simultaneity shifted so that the assumed cause B appeared earlier and the assumed effect C later, despite full attention and repeated viewings. This first demonstration of causality reversing perceived temporal order cannot be explained by post-perceptual distortion, lapsed attention, or saccades. (shrink)

Since the discovery of incommensurability in ancient Greece, arithmeticism and geometricism constantly switched roles. After ninetieth century arithmeticism Frege eventually returned to the view that mathematics is really entirely geometry. Yet Poincaré, Brouwer, Weyl and Bernays are mathematicians opposed to the explication of the continuum purely in terms of the discrete. At the beginning of the twenty-first century ‘continuum theorists’ in France (Longo, Thom and others) believe that the continuum precedes the discrete. In addition the last 50 years witnessed the (...) revival of infinitesimals (Laugwitz and Robinson—non-standard analysis) and—based upon category theory—the rise of smooth infinitesimal analysis and differential geometry. The spatial whole-parts relation is irreducible (Russell) and correlated with the spatial order of simultaneity. The human imaginative capacities are connected to the characterization of points and lines (Euclid) and to the views of Aristotle (the irreducibility of the continuity of a line to its points), which remained in force until the ninetieth century. Although Bolzano once more launched an attempt to arithmetize continuity, it appears as if Weierstrass, Cantor and Dedekind finally succeeded in bringing this ideal to its completion. Their views are assessed by analyzing the contradiction present in Grünbaum’s attempt to explain the continuum as an aggregate of unextended elements (degenerate intervals). Alternatively a line-stretch is characterized as a one-dimensional spatial subject, given at once in its totality (as a whole) and delimited by two points—but it is neither a breadthless length nor the (shortest) distance between two points. The overall aim of this analysis is to account for the uniqueness of discreteness and continuity by highlighting their mutual interconnections exemplified in the nature of a line as a one-dimensional spatial subject, while acknowledging that points are merely spatial objects which are always dependent upon an extended spatial subject. Instead of attempting to reduce continuity to discreteness or discreteness to continuity, a third alternative is explored: accept the irreducibility of number and space and then proceed by analyzing their unbreakable coherence. The argument may be seen as exploring some implications of the view of John Bell, namely that the “continuous is an autonomous notion, not explicable in terms of the discrete.” Bell points out that initially Brouwer, in his dissertation of 1907, “regards continuity and discreteness as complementary notions, neither of which is reducible to each other.”. (shrink)

This article investigates the claims made in the dedicatory epistle to Girolamo Manfredi’s De homine to have effected an Italian translation of various earlier works. First published in 1474, the De homine is strongly dependent on the pseudo-Aristotelian Problems, for which several translations into Latin were available by Manfredi’s time as well as the highly influential commentary by Pietro d’Abano. Focusing on one particular section of the De homine, on voice, this article offers an analysis of the various sources used (...) and of the extent to which Manfredi is indeed offering a translation or something different. This study concludes that Manfredi closely followed the translation by Bartolomeo da Messina and the commentary by Pietro d’Abano; it finds no clear evidence of his use of the translations by George of Trebizond or Theodore Gaza. Other sources used include especially Rhazes’ Ad Almansorem. (shrink)

The “erasing race” effect is the reduction of the salience of “race” as an alliance cue when recalling coalition membership, once more accurate information about coalition structure is presented. We conducted a random-effects model meta-analysis of this effect using five United States studies (containing nine independent effect sizes). The effect was found (ρ = 0.137, K = 9, 95% CI = 0.085 to 0.188). However, no decline effect or moderation effects were found (a “decline effect” in this context would be (...) a decrease in the effect size over time). Furthermore, we found little evidence of publication bias. Synthetically correcting the effect size for bias stemming from the use of an older method for calculating error base rates reduced the magnitude of the effect, but the it remained significant. Taken together, these findings indicate that the “erasing race” effect generalizes quite well across experimental contexts and would, therefore, appear to be quite robust. We reinterpret the theoretical basis for these effects in line with Brunswikian evolutionary-developmental theory and present a series of predictions to guide future research in this area. (shrink)

A line of research is emerging investigating the private sector impacts and dependencies on critical biodiversity and ecosystem services, and related business risks and opportunities. While the ecosystem services narrative is being forwarded globally as a key paradigm for promoting business sustainability, there is scarce knowledge of how these issues are considered at managerial level. This study thus investigates managerial views of corporate sustainability after the ecosystem services concept. We analyse interviews conducted with 20 managers from domestic and international forestry (...) companies operating with a plantation-based business model in China. Content analysis was employed to analyse the data, with a focus on four key areas: interviewee familiarity with the ecosystem services concept; their views of corporate dependencies and impacts on ecosystem services; related business risks and opportunities; and viability of existing instruments and practices that can be employed in detecting and addressing business impacts and dependencies on ecosystem services. Through an inductive approach to the empirical findings, we refined a framework that holds operational value for developing company response strategies to ecosystem services impact/dependence assessment, ensuring that all issues are addressed comprehensively, and that related risks and opportunities are properly acknowledged. (shrink)

This article investigates the claims made in the dedicatory epistle to Girolamo Manfredi’s De homine to have effected an Italian translation of various earlier works. First published in 1474, the De homine is strongly dependent on the pseudo-Aristotelian Problems, for which several translations into Latin were available by Manfredi’s time as well as the highly influential commentary by Pietro d’Abano. Focusing on one particular section of the De homine, on voice, this article offers an analysis of the various sources used (...) and of the extent to which Manfredi is indeed offering a translation or something different. This study concludes that Manfredi closely followed the translation by Bartolomeo da Messina and the commentary by Pietro d’Abano; it finds no clear evidence of his use of the translations by George of Trebizond or Theodore Gaza. Other sources used include especially Rhazes’ Ad Almansorem. (shrink)

The different aspects of floral evolution—Angiosperm descent, floral morphology and pollination ecology—are discussed on the basis of the anthocorm theory of the angiospermous flower. Opposed ideas are critically compared and rejected mainly on account of several inconsistencies and flaws in old floral concepts. Floral evolution passed from a very early phase of dicliny, anemophily and aphananthy of the anthocorm to a phase of incipient entomophily soon associated with a partial sex reversal within the anthocorm. This second phase culminated in the (...) monoclinous and primarily zoophilous flower types, whereas other floral types, more particularly the primarily anemophilous, diclinous flowers, are the direct descendants of the anthocorms of the initial phase. The second phase gave rise to at least two morphologically different flower types and two separate semophyletic lines of floral evolution , in each of which the primary zoophily is almost always associated with the development of intrafloral semaphylls usually of androecial derivation. Early flower types were aphananthous and clearly anthocormoid and assumed the morphology and other characteristics of a true flower by contractions, condensations, readjustments, oligomerisations, reductions and modifications leading to the great variety of adaptive floral patterns.Divers aspects de l'évolution de la fleur — à savoir la descendance des Angiospermes, la morphologie de la fleur, et l'écologie de la pollination — sont discutés à partir de l'hypothèse florale de l'anthocorme. Les opinions opposées, après d'être comparées et critisées, sont rejetées principalement à cause des inconséquences et inconsistances des anciens théorèmes morphologiques concernant l'origine de la fleur. L'évolution de la fleur commençait avec une phase d'antan de diclinie, anémophilie et aphananthie, et s'avançait graduellement dans la direction d'une phase entomophilique initiale, bientôt accompagnée d'un renversement de sexe partiel à l'intérieur de l'anthocorm. La deuxième phase culminait vers les types florals monoclines avec zoophilie primaire pendant que des autres types florals, particulièrement les fleurs diclines avec anémophilie primaire, sont les descendants directs du stade initiale de l'anthocorme. A partir de la phase II , au moins deux types florals différents et aussi deux sémophylèses florals séparés se développaient. Dans chacun de ses phases III et III A la zoophilie primaire est presque toujours accouplée avec l'origine des sémaphylles intrafloraux le plus souvent dérivés des étamines. Les anciens types des fleurs ayant été aphanantique et au début encore nettement anthocormoïdes , graduellement prenaient la forme d'une des plusieurs types floraux adaptifs par une contraction de l'axe florale et par l'entassement, l'oligomérisation et la modification des pièces de la fleur.Die drei Aspekte der Evolution der Blüte — die Abstammungsgeschichte der Angiospermen, Blütenmorphologie und Bestäubungsökologie — werden, ausgehend von der Anthokormtheorie der Angiospermenblüte, eingehend besprochen. Entgegengesetzte Meinungen werden kritisch verglichen und hauptsächlich auf Grund mehrerer Strittigkeiten und Fehler der älteren blütenmorphologischen Axiomen abgelehnt. Die Evolution der Blüte fing an mit einer frühen Phase mit Diklinie, Anemophilie und Aphananthie des Anthokorms und schritt allmählich weiter in die Richtung von beginnender Entomophilie, bald mit einer partiellen Geschlechtsinversion innerhalb des Anthokorms zusammengehend. Diese zweite Phase kulminierte in den monoklinen und primär zoophilen Blütentypen, während andere Blütengestalten, besonders die primär anemophilen und diklinen Angiospermenblüten, die unmittelbaren Abkömmlinge der Initialphase des Anthokorms sind. Aus der zweiten Phase entwickelten sich wenigstens zwei morphologisch differenzierte Blütenformen und auch zwei geschiedene Blütensemophylesen , in jeder die primäre Zoophilie fast immer verbunden ist mit der Entwicklung von intrafloralen und meistens von Staubblättern angeleiteten Semaphyllen . Die frühen Blütentypen waren aphanantisch und anfänglich noch deutlich anthokormoid und nahmen allmählich die entgültige Gestalt von einer der vielen adaptiven Blütentypen an durch eine Verkürzung der Blütenachse, und durch ein Zusammendrängen, Oligomerisation und Abänderung der Blütenteile. (shrink)

The field of AI safety aims to prevent increasingly capable artificially intelligent systems from causing humans harm. Research on moral alignment is widely thought to offer a promising safety strategy: if we can equip AI systems with appropriate ethical rules, according to this line of thought, they'll be unlikely to disempower, destroy or otherwise seriously harm us. Deontological morality looks like a particularly attractive candidate for an alignment target, given its popularity, relative technical tractability and commitment to harm-avoidance principles. I (...) argue that the connection between moral alignment and safe behavior is more tenuous than many have hoped. In general, AI systems can possess either of these properties in the absence of the other, and we should favor safety when the two conflict. In particular, advanced AI systems governed by standard versions of deontology need not be especially safe. (shrink)

Down to the present century the Niobe of Aeschylus was represented by eight significant manuscript fragments containing some twenty-three lines. Even in this condition it deservedly attracted the interest and attention of scholars; and in 1933 this interest was intensified by the publication in Florence by Vitelli and Norsa of a mutilated papyrus of twenty-one lines embodying two of the earlier fragments.

Down to the present century the Niobe of Aeschylus was represented by eight significant manuscript fragments containing some twenty-three lines. Even in this condition it deservedly attracted the interest and attention of scholars; and in 1933 this interest was intensified by the publication in Florence by Vitelli and Norsa of a mutilated papyrus of twenty-one lines embodying two of the earlier fragments.

Long noncoding RNAs have been described in cell lines and various whole tissues, but lncRNA analysis of development in vivo is limited. Here, we comprehensively analyze lncRNA expression for the adult mouse subventricular zone neural stem cell lineage. We utilize complementary genome-wide techniques including RNA-seq, RNA CaptureSeq, and ChIP-seq to associate specific lncRNAs with neural cell types, developmental processes, and human disease states. By integrating data from chromatin state maps, custom microarrays, and FACS purification of the subventricular zone lineage, (...) we stringently identify lncRNAs with potential roles in adult neurogenesis. shRNA-mediated knockdown of two such lncRNAs, Six3os and Dlx1as, indicate roles for lncRNAs in the glial-neuronal lineage specification of multipotent adult stem cells. Our data and workflow thus provide a uniquely coherent in vivo lncRNA analysis and form the foundation of a user-friendly online resource for the study of lncRNAs in development and disease. © 2013 Elsevier Inc. (shrink)

On-line, just as off-line, there are ways of assessing the credibility of information sources. The Internet, although it arguably makes for nothing wholly new in this regard, complicates the ordinary task of assessing credibility. In the first section, I consider a specific example and argue that Internet content providers have no clear interest in resolving these comlications. In the second, I consider four general ways that we might assess credibility and explore how they apply to life online. Finally, I argue (...) that even careful information gathering may pose subtle pitfalls but that some of these may be mitigated on-line. (shrink)

Multilevel research strategies characterize contemporary molecular inquiry into biological systems. We outline conceptual, methodological, and explanatory dimensions of these multilevel strategies in microbial ecology, systems biology, protein research, and developmental biology. This review of emerging lines of inquiry in these fields suggests that multilevel research in molecular life sciences has significant implications for philosophical understandings of explanation, modeling, and representation.

The workplace is characterised by numerous contracts of agreement that an employee and employer must sign to formalise their employment relationship. The informal agreement, known as the psychological contract, is often overlooked, although it is pivotal in determining the engagement of employees in an organisation. This study aimed to probe the perceptions line managers have of the influence of the psychological contract on employee engagement in a South African bank with a particular focus on how the integration of technologies from (...) the Fourth Industrial Revolution may have impacted the workplace in the banking sector. The study was carried out using a qualitative research approach. A purposive random sampling strategy was used to select participants who were interviewed using semi-structured, one-on-one interviews. The data collected were analysed using thematic analysis, and verbatim quotes were used to support emergent themes. The findings of the study revealed that continuous change in the world, exacerbated by the COVID-19 pandemic, influences employee expectations. Thus, organisations must be able to quickly adapt and adjust their talent attraction and retention mechanisms. Talent management, the nature of the business, structure and operations, the nature of the work environment, and emotional needs are the themes that emerged from the study. With the constant change in the world of work, including industry disruptions continually imposed by the 4IR and other factors, employees’ expectations are ever-changing. Thus, organisations must keep adapting to attract and retain talent. This study adds value by addressing various aspects aligned with competitively adjusting to the current and future world of work. (shrink)

This article presents the results of an inductive, interpretive case study. We have adopted a narrative approach to the analysis of organizational processes in order to explore how individuals in a financial institution dealt with relatively novel issues of corporate social responsibility (CSR). The narratives that we reconstruct, which we label 'idealism and altruism', 'economics and expedience' and 'ignorance and cynicism' illustrate how people in the specific organizational context of a bank ('Credit Line') sought to cope with an attempt at (...) narrative imposition. In particular, our work exemplifies how people in organizations draw on shared discursive resources in order to make sense of themselves and their organizations. We illustrate how many people within the bank found it hard to integrate the normative case for CSR with their version of a narrative identity which had, and continued to be, centred on economic imperatives for new initiatives. Our article demonstrates both the value of the analysis of shared narratives, and represents an attempt to deal adequately with the polyphony of organizational voices, in case studies of CSR. (shrink)

En 1986, H.T. Engelhardt justifiait l'autonomie de la bioéthique à l'égard des éthiques religieuses en partant du fait que les hommes de notre temps sont « moralement des étrangers », les uns pour les autres. En 1991, il entreprit de mieux discerner les relations entre éthiques séculière et religieuse, en gardant la même orientation de pensée, mais en s'attaquant à l'idéologie d'un humanisme athée. Il cherche à établir sur les bases d'une rationalité universelle un « cadre de référence neutre », (...) commun à l'ensemble des partenaires du débat éthique contemporain, mais qui laisserait la place à une pluralité de visions philosophiques, religieuses et morales. Car ce serait ruiner toute éthique que de vouloir fonder la bioéthique sur le seul recours au consentement libre et éclairé du malade et sur le respect de son autonomie, à l'exclusion de toute recherche de « buts transcendants ». – La pensée d'Engelhardt n'est pas exempte d'ambiguïtés sinon de contradictions : il ne dit pas comment son humanisme séculier donnera satisfaction aux partisans des éthiques religieuses ni quel sera le statut institutionnel de ce cadre de référence commun ni quelle issue il propose entre le nihilisme et le relativisme moral ni sur quelle base pourrait se faire une hiérarchisation des valeurs dans une bioéthique séculière. Sa pensée devrait se prolonger en direction des droits de l'homme, mieux distinguer entre principes premiers et principes dérivés, creuser davantage le concept de subjectivité.In 1986 H. T Engelhardt justified the autonomy of bioethics as regards religious ethics by starting with the fact that people in our day are “moral strangers” in regard to each other. In 1991 he studied further the relations between secular and religious ethics while keeping the same line of thougbt, but in attacking the ideology of atheistic humanism. He is trying to establish, on the basis of a universal rationality, a “neutral framework “ that would be shared by all those debating contemporaneous ethics. It would leave room for a plurality of philosophical, religious, and moral visions, For it would destroy all ethics if one wished to base bioethics only on trying to get a free and enlightened agreement from the patient and on the respect of his autonomy, in exclusion of every search.for « transcendental ends ». The thougbt of Engelhardt is not free from ambiguities, if not contradictions: he doesn't say how his secular humanism will give satisfaction to the supporters of religious ethics; nor what the institutional status of tbis common framework would be; nor what he proposes as the way out between nihilism and moral relativism; nor on what basis a hierarchy of values could be created in secular bioethics. His ideas call for further reflection : found etbics on the rights of man; distinguish more clearly between first principles and principles that are derived ; and dig deeper into the concept of subjectivity. (shrink)

An examination of the contemporary Italian movement associated with M. P. Sciacca, and the serious application of dialectical and phenomenological methods to unveil the structure of "intentionality" or "spirit." An appraisal of Sciacca together with a sample critique of Dante follows a competent summary of the prevailing positions.--D. B. B.

the famous passage at the end of the sixth book of the Republic, in which Socrates compares our cognitive states to different sections of a single line, is often read as a "map" of Plato's epistemology. Symbolizing the different levels of cognition, the divided line may be taken to present a forceful image of the various stages that the soul must traverse in its quest for true knowledge. Its reputation as a snapshot of the epistemology of Plato's mature dialogues makes (...) the divided line, despite, or perhaps because of, persisting disagreements over its interpretation, one of the most vexed passages of the Platonic corpus.In the ancient readings of the divided line, many of the modern exegetical debates... (shrink)

Recent research has focused on business as a mediating institution that can influence society while engaging in the traditional profit-making and value generation functions. This work includes Professors Fort's and Schipani's arguments about how business may be able to play a role in promoting more peaceful societies, and other research addressing how businesses might serve a role in reducing violence in society and the workplace. Although there is a significant body of scholarship on the role of business in reducing violence (...) in society, there is little research on concrete steps for businesses to take to achieve this goal. This article attempts to begin to fill that void. As identified by Fort and Schipani, business may promote more peaceful societies by encouraging a sense of community. We argue that one way to reach that goal is for business to provide what we denote as complementary alternative benefits (CABs), to its workforce. In this article, we advocate for businesses to offer CABs which focus on sustaining the health, reducing the stress, and improving the camaraderie of its workforce. We argue that business can use these benefits to promote a healthy, less-stressed, and collegial workforce that is less prone to resolve conflicts by violence. Further, we examine the role business plays in promoting more peaceful societies and how employer-initiated stress reduction programs are consistent with both business ethics and peace-building principles. Finally, using case studies we demonstrate how CABs may also reduce costs related to absenteeism and turnover, and thus improve the bottom line. (shrink)

Ethical decision support procedures have an underlying difficulty in that they do not clearly distinguish the varying impacts of the constituent features of the examined ethical situation. The failure to recognize these features and their varying impacts leads to two critical problems; the risk of removing positive ethical elements as well as negative ones when mitigating the ethical problem, and missing some viable alternative actions. A modified version of line drawing is presented as a way to address these two problems (...) when it is used as an adjunct to already established decision techniques. (shrink)

I have argued in other work that emotion, attentional functions, and executive functions are three interpenetrant global state variables, essentially differential slices of the consciousness pie. This paper will outline the columnar architecture and connectivities of the PAG (periaqueductal gray), its role in organizing prototype states of emotion, and the re-entry of PAG with the extended reticular thalamic activating system (“ERTAS”). At the end we will outline some potential implications of these connectivities for possible functional correlates of PAG networks that (...) are just starting to be mapped. Overall, we will look at many lines of evidence that PAG should be conceptualized as a peri-reticular structure that has a foundational role in emotion, in generating the meaningful organization of behavior by the brain through prototype emotional states, and in allowing the various emotional systems to globally influence and tune both the forebrain and brainstem. Finally, we address implications of these concepts for what is currently understood about consciousness, underlining the need for somewhat more humility within consciousness studies about our current level of understanding of consciousness in the brain, combined with a deeper appreciation of the intrinsic connections between emotion and consciousness. One hopes that more concerted empirical interest in structures underneath the thalamus, combined with a deeper appreciation for the fundamental role that organismic and social value must have in bootstrapping awareness in the developing brain, would begin more widely to influence the fundamental lines of neuroscientific research in both emotion studies and consciousness studies. (shrink)

Requests for support in professional changes are getting more and more numerous. Regarding jobs concerned with caring for others, therapeutic education needs to be spread into new approaches requiring social and human sciences (Tourette-Turgis, 2015 ; Chalmel, 2015). These requests lead to alterations in professional practices and changes in educational devices. This chapter deals with a direct observation of effective practices addressed to young patients and also implies the training of nurses through experiences. It also discusses ways of scientific collaboration (...) between female researchers in different scientific fields of the medical body leading the latter to alter their practices by creating pedagogic instruments or new tools for training. This inventive conception deriving from these exchanges leaning on experiences and skills previously built up and linked together to help devices development. Our contribution deals with and discusses the transformation of state nurses functions through these analyses and towards actions which do not only concern body care but a way of teaching healthy life style. The themes under study concerns the passing on and transferring experiences and responsibility when directing cessions from cardiology education to the therapeutic education nurse. (shrink)

Along with a line by line translation and interpretation of the fragments, are four essays: "Parmenides' Concept of Being," "Aletheia and Doxa," "The World of Appearance Described in the Doxa," and "Parmenides in the Ancient Philosophical Tradition." Parmenides did not understand the logical connection between time and process: undifferentiated Being is without process but, curiously enough, possesses temporal duration. The philosophical tradition wrongly interpreted the Doxa as Parmenides' cosmogony. In short, this important book is a splendid example of painstaking scholarship. (...) The footnotes and references to other critical studies of Parmenides are comprehensive.—D. J. B. (shrink)

This article presents factors and criteria of interview in auto-confrontation with an objective of professional didactic, which we frequently conduct in our collaborative researches, when we analyze the activity. Our aim is to initiate reflections and debates about the status conferred to auto-confrontation in a process of research and about the issue answers by such method in professional training. Observing that auto-confrontation is discussing in human and social sciences as a tool of investigation, as a method or as scientific object, (...) we try to identify dimensions that make it to be both a method of investigation and a tool of professional training. Since we explain why auto-confrontation considering in theoretical context of professional didactic constitutes a tool for professional involvement, and that, in such case, it integration in vocational training engineering is relevant. (shrink)

The didactic proposal of the post-constructivist (Grossi, 2005), takes into account the relationship between the subject, reality, others and the Other interior and considers the learning potential of all students. Its theoretical foundation is, among other things, the principle that learning is a social phenomenon, and that the spatial organization of the class, in groups of adults, promotes the teaching-learning process. Post-constructivism is a didactic proposition that allows us to respond to the purpose of teaching all students. This article on (...) group work in post-constructivism aims to analyze the change in posture of teachers, and the professional development that follows, and which demonstrates a break with the traditional form of education. The trick of the identified researcher is then to take up in a teacher training, through the aulic groups in the Geempa class and the weekly study group, the scientific approach of post-constructivism. (shrink)

This study investigates the ability of individuals with psychopathy to perform passive avoidance learning and whether this ability is modulated by level of reinforcement/punishment. Nineteen psychopathic and 21 comparison individuals, as defined by the Hare Psychopathy Checklist Revised (Hare, 1991), were given a passive avoidance task with a graded reinforcement schedule. Response to each rewarding number gained a point reward specific to that number (i.e., 1, 700, 1400 or 2000 points). Response to each punishing number lost a point punishment specific (...) to that number (i.e., the loss of 1, 700, 1400 or 2000 points). In line with predictions, individuals with psychopathy made more passive avoidance errors than the comparison individuals. In addition, while the performance of both groups was modulated by level of reward, only the performance of the comparison population was modulated by level of punishment. The results are interpreted with reference to a computational account of the emotional learning impairment in individuals with psychopathy. (shrink)

Drawing on a global sample of microfinance institutions (MFIs), this paper offers insights into the trade-off versus synergy debate of adopting multiple institutional goals in hybrid organisations. Additionally, it unravels which organisation- and country-specific determinants associate with top joint performance using machine-learning techniques. We find that the synergy versus trade-off debate is not dichotomous. Rather, MFIs can be strong both socially and financially but not while charging low interest rates. In our sample, 17% of MFIs serve a low-income clientele in (...) need with a diverse range of services while remaining financially sustainable and ask a close-to-average interest rate. These organisations are larger and more mature as well as financially prudent in that they minimize both financial and credit risk. Moreover, they are located in countries where their services can create larger benefits regarding their underlying goals. (shrink)

Si indagano le elaborazioni prodotte da Savonarola e da Valenza sulla filosofia morale, cercando di porre in evidenza elementi comuni e punti di distanza tra i due, soffermandosi in particolare sul modo in cui essi studiarono il rapporto tra etica dei pagani ed etica cristiana, prendendo le distanze dalla posizione assunta precedentemente da Tommaso d'Aquino. Le opere studiate sono il Compendium philosophiae moralis di Savonarola e il Compendium Ethicorum Aristotelis scritto da Valenza. Si giunge così a comprendere che, sebbene l'insegnamento (...) impartito negli studia dell'ordine domenicano non lo prevedesse strettamente, l'Etica e la Politica di Aristotele erano ben conosciute dai domenicani del 1400, compendiate e studiate spesso a partire proprio dai commenti dell'Aquinate. (shrink)

You find yourself in a court of law, accused of having hit someone. What can you do to avoid conviction? You could simply deny the accusation: 'No, I didn't do it'. But suppose you did do it. You may then give a different answer. 'Yes, I hit him', you grant, 'but it was self-defence'; or 'Yes, but I was acting under duress'. To answer in this way-to offer a 'Yes, but...' reply-is to hold that your particular wrong was committed in (...) exceptional circumstances. Perhaps it is true that, as a rule, wrongdoers ought to be convicted. But in your case the court should set the rule aside. You should be acquitted. Within limits, the law allows for exceptions. Or so we tend to think. In fact, the line between rules and exceptions is harder to draw than it seems. How are we to determine what counts as an exception and what as part of the relevant rule? The distinction has important practical implications. But legal theorists have found the notion of an exception surprisingly difficult to explain. This is the longstanding jurisprudential problem that this book seeks to solve. The book is divided into three parts. Part I, Defeasibility in Question, introduces the topic and articulates the core puzzle of defeasibility in law. Part II, Defeasibility in Theory, develops a comprehensive proof-based account of legal exceptions. Part III, Defeasibility in Action, looks more closely into the workings of exceptions in accusatory contexts, including the criminal trial. (shrink)

In recent times the question of whether or not there is such a thing as nonconceptual content has been the object of much serious attention. For analytical philosophers, the locus classicus of the view that there is such a phenomena is to be found in Evans remarks about perceptual experience in Varieties of Reference. John McDowell has taken issue with Evans over his claim that "conceptual capacities are first brought into operation only when one makes a judgement of experience, and (...) at that point a different species of content comes into play" (McDowell 1994: 48). In contrast, he proposes that "A judgement of experience does not introduce a new kind of content, but simply endorses the conceptual content, or some of it, that is already possessed by the experience on which it is grounded" (McDowell 1994: 48-49). Ironically, in light of the ambitions of Mind and World, this sits very happily with the firmly embedded views of many traditional classical cognitivists. It has been a long-standing article of faith that, even in its most basic forms, perceptual content must be conceptual. But those who adopt this position have a heavy burden when it comes to explaining the origin and development of concepts (cf. Peacocke 1992a: 9). In line with the proposal that at least some primitive concepts must be innate, theorists like Fodor make appeal to the intrinsic character of such concepts to explain more complex conceptual contents and their essential characteristics (Fodor 1998: 130). Primitive concepts and their properties as simply assumed because of an explanatory need despite that fact that making this assumption has a paradoxical consequence --which, in this case, is revealed by Fodor's claim that all concepts must be acquired inductively (cf. Fodor 1998: 130-132). The good news is that if we opt for a nonconceptualist approach then we need not assume that any concepts are innate. There is a plausible programme afoot, initiated by Cussins, which hopes explain "the construction of cognitive properties out of non-cognitive properties" (Cussins 1990: 374). He encourages us to suppose "that the mind/world distinction is a phylogenetic or ontogenetic achievement" (Cussins 1990: 409). However, some advocates of nonconceptual content believe that providing this explanation will be a relatively straightforward, although clearly difficult, task given that a contentful base of nonconceptual informational states, of the kind Evans envisioned, is presupposed. My aim is to defend Evans but if if nonconceptual content is to play the important role assigned to it of helping to explain the development of concepts then we must explicate the nature of such content in such a way that does not presuppose that it is truth-conditional. We must also be able to say exactly what part nonconceptual responses play in judgement making and conceptual development. It is the burden of this paper to provide a sketch of how both these ends might be achieved and to offer some reasons for thinking the project is a viable one. I do this in two stages. The first is to advocate a modest biosemantic theory of nonconceptual content and the second is to show how this can shore up a Davidsonian understanding of the possession conditions for concepts. (shrink)

The generality problem is perhaps the most notorious problem for process reliabilism. Several recent responses to the generality problem have claimed that the problem has been unfairly leveled against reliabilists. In particular, these responses have claimed that the generality problem is either (i) just as much of a problem for evidentialists, or (ii) if it is not, then a parallel solution is available to reliabilists. Along these lines, Juan Comesaña has recently proposed solution to the generality problem—well-founded reliabilism. According (...) to Comesaña, the solution to the generality problem lies in solving the basing problem, such that any solution to the basing problem will give a solution to the generality problem. Comesaña utilizes Conee and Feldman’s evidentialist account of basing (Conee and Feldman’s well-foundedness principle) in forming his version of reliabilism. In this paper I show that Comesaña’s proposed solution to the generality problem is inadequate. Well-founded reliabilism both fails to solve the generality problem and subjects reliabilism to new damning verdicts. In addition, I show that evidentialism does not face any parallel problems, so the generality problem remains a reason to prefer evidentialism to reliabilism. (shrink)

Little is known about the consequences of moral distress. The purpose of this study was to identify clinical situations that caused nurses to experience moral distress, to understand the consequences of those situations, and to determine whether nurses would change their practice based on their experiences. The investigation used a descriptive approach. Open-ended surveys were distributed to a convenience sample of 204 critical care nurses employed at a university medical center. The analysis of participants’ responses used an inductive approach and (...) a thematic analysis. Each line of the data was reviewed and coded, and the codes were collapsed into themes. Methodological rigor was established. Forty-nine nurses responded to the survey. The majority of nurses had experienced moral distress, and the majority of situations that caused nurses to experience moral distress were related to end of life. The nurses described negative consequences for themselves, patients, and families. (shrink)